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YALÇIN, AHMET SUHA

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YALÇIN

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AHMET SUHA

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2016 - 20192
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Author: YILMAZ GÖLER, AYŞE MİNE × Subject: OXIDATIVE STRESS ×

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Now showing 1 - 2 of 2
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    PublicationOpen Access
    Anti-cancer effects of curcumin, quercetin and tea catechins
    (MARMARA UNIV, FAC PHARMACY, 2016-09-20) YALÇIN, AHMET SUHA; Yalcin, A. Suha; Yilmaz, Ayse Mine; Altundag, Ergul Mutlu; Kocturk, Semra
    Polyphenols are present in high amounts in all parts of plants including roots, seeds, flowers, leaves, branches and trunk as well as plant derived products such as tea, coffee and wine. Extensive amount of information is available on biological effects of polyphenols including antioxidant, anti-cancer, anti-inflammatory, anti-coagulant and anti-microbial activities. In recent years, researchers have turned their interest towards identifying molecular mechanisms underlying the anti-cancer effects of these compounds. However, the limited bioavailability of polyphenols and the existence of differences in cancer cells in terms of intracellular mechanisms affected has necessitated the use of specific approaches to individual cancer cell types as well as methods of increasing bioavailability. In this review, the structures, bioavailability, biological activities and molecular mechanisms of anti-cancer effects of curcumin, quercetin and tea catechins are discussed.
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    PublicationOpen Access
    Effect of casein and whey proteins on examination stress
    (MARMARA UNIV, FAC MEDICINE, 2019-05-28) YALÇIN, AHMET SUHA; Celik, Ramazan; Kaymakci, Mahmut Sami; Akalin, Deniz; Karademir, Enes; Tuncer, Behlul; Bicim, Gokhan; Yilmaz, Ayse Mine; Yalcin, A. Suha
    Objective: In this study we aimed to evaluate the effects of casein and whey protein supplementation on examination stress. We have investigated different parameters of oxidative stress and immune function. Materials and Methods: The participants were divided into three groups: control, casein and whey. Casein and whey groups were supplemented with either casein or whey protein for 15 days. Blood samples were obtained at the beginning of the study (Day 0), on the examination day (Day 16) and five days after the examination (Day 21). Antioxidant capacity, glutathione, cortisol and cytokine levels (TNF-a, IL-6, IL-12) were measured. Results: An increase in antioxidant capacity and glutathione levels of the participants using whey protein was observed. Whey protein supplementation did not affect cortisol levels, but participants taking whey protein showed an increase in serum TNF-a and IL-6 levels. Conclusion: It is suggested that the use of whey protein strengthens the response to oxidative stress by increasing antioxidant capacity and glutathione levels, while supporting the immune system via cytokine release.