Person: ERMERAK, NEZİH ONUR
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ERMERAK
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NEZİH ONUR
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Publication Metadata only Epithelioid malignant pleural mesothelioma: Importance of extrapleural lymph node metastasis and trimodality treatment(2015-05-31) ERMERAK, NEZİH ONUR; LAÇİN, TUNÇ; AHISKALI, ASİYE RENGİN; YILDIZELİ, BEDRETTİN; BATIREL H. F., ERMERAK N. O., LAÇİN T., METİNTAŞ M., AK G., YUMUK P. F., ÖZKÖK H. B., AHISKALI A. R., YILDIZELİ B., YÜKSEL M.Publication Metadata only Pektus karinatumun minimal invaziv yöntemle tedavisi(2018-05-01) ERMERAK, NEZİH ONUR; YÜKSEL M., ERMERAK N. O.Pektus Karinatum (PK) ikinci en sık görülen konjenital göğüs duvarı deformitesidir. Ergenlikle birlikte deformite belirginleşerek kozmetik ve psikososyal sorunlara yol açmaktadır. Günümüzde Pektus Karinatum'un cerrahi tedavisinden Minimal Invaziv Yöntemle Pektus Karinatum Onarımı (MIRPC) tercih edilen tedavi metodu halini almıştır. Bu bölümde; operasyonun preoperatif ve postoperatif süreci ile birlikte cerrahi teknik ile ilgili bilgiler aktarılması amaçlanmıştır.Publication Metadata only Preoperative Chemoradiation Therapy Decreases the Number of Lymph Nodes Resected During Esophagectomy(SPRINGER, 2015) ÇELİKEL, ÇİĞDEM; Issaka, Adamu; Ermerak, Nezih Onur; Bilgi, Zeynep; Kara, Volkan Hasan; Celikel, Cigdem Ataizi; Batirel, Hasan FevziBackground This study aimed to analyze the effect of preoperative chemoradiation on the adequacy of lymph node dissection. Methods Patients with esophageal cancer treated with esophagectomy by the same surgeon between 2004 and 2011 were reviewed. Specimens were examined by the same pathologist. Patients were grouped into two depending on the type of treatment received. Results Forty-seven patients with curative esophagectomy were included in the study. Twenty patients had preoperative chemoradiation followed by surgery and 27 had surgery alone. Open and hybrid esophagectomy approaches were used. The average number of lymph nodes dissected was 16 +/- 10 (1-39). There was a significant decrease in the number of lymph nodes examined in patients with preoperative chemoradiotherapy in comparison to surgery alone (p = 0.001). Median length of stay was 12 days. R0 resection rate was 96 %. The median survival was 36.3 months, with a 42 % 5-year survival. Seven patients (25 %) had complete pathologic response following chemoradiation. No significant difference was recorded in terms of disease recurrence (p = 0.3). While morbidity was higher in the preoperative therapy group with 30 day mortality of 10 %, type of surgical approach does not seem to influence the number of lymph nodes dissected (p = 0.7). Conclusions Preoperative chemoradiation decreases the number of harvested lymph nodes following esophagectomy regardless of the surgical technique used. The optimum number of lymph nodes currently recommended to be dissected for accurate nodal staging and survival needs revision in this group of patients.Publication Metadata only Reconstruction of sternal cleft with autologous cartilage graft in an adult(2015-06-01) ERMERAK, NEZİH ONUR; BOSTANCI, KORKUT; YÜKSEL, MUSTAFA; KURU P., ERMERAK N. O., BOSTANCI K., YÜKSEL M.Sternal cleft is a rare chest wall deformity associated with various malformations. Primary closure is the gold standard in the newborn period. Alternative techniques are possible for older patients. A 23-year-old woman with a partial sternal cleft and no additional deformity, underwent reconstruction using costal cartilage grafts. Postoperative physical and functional were excellent.Publication Open Access Surgical outcomes of patients with non-small cell lung cancer following neoadjuvant treatment(MARMARA UNIV, FAC MEDICINE, 2018-10-31) ERMERAK, NEZİH ONUR; Ocakcioglu, Ilhan; Alpay, Levent; Ermerak, Nezih Onur; Kiral, Hakan; Tezel, Cagatay; Baysungur, Volkan; Yalcinkaya, IrfanObjective: Although, anatomical resection of non-small cell lung cancer (NSCLC) following neoadjuvant therapy is still controversial, it is a widely accepted approach for thoracic surgery practice. The aim of this study is to briefly evaluate clinical results, long term survival, and factors affecting survival of the patients with locally advanced NSCLC, pancoast tumour and lung cancer with solitary brain metastasis, who have been operated at our institution following neoadjuvant therapy. Materials and Method: Between March 2006 and March 2012, 70 patients with NSCLC diagnosis who underwent anatomic pulmonary resection following neoadjuvant therapy were included in the study. Results: A three year survival (39%) and a 5-year survival (29%) were 16 +/- 6.8 and 37 +/- 9.89 months, respectively. The mean survival was found to be 37.15 +/- 3.06 months. When survival rate was evaluated according to localization of tumor, it was lower in central and left upper lobe tumors compared to other anatomical localizations (P=0.042). The mean 5-year survival times were 50.00 +/- 5.65 months in stage 0 patients, 35.39 +/- 5.85 months in stage 1 patients, 37.40 +/- 6.89 months in stage 2 patients and 21.44 +/- 3.10 months in stage 3 patients. Conclusion: We can achieve significant survival results by the anatomical pulmonary resection following neoadjuvant therapy.Publication Open Access Minimally Invasive Repair of Pectus Carinatum(ELSEVIER SCIENCE INC, 2018-03) ERMERAK, NEZİH ONUR; Yuksel, Mustafa; Lacin, Tunc; Ermerak, Nezih Onur; Sirzai, Esra Yamansavci; Sayan, BihterBackground. The second most common deformity of the anterior chest wall, pectus carinatum, is a diverse deformity that has been largely managed using open techniques. This study reviews clinical experience with a newly designed bar for minimally invasive repair of pectus carinatum. Methods. We reviewed the records of all patients recorded in our Chest Wall Deformities Clinical Database. Between January 2006 and November 2016, minimally invasive repair of pectus carinatum was performed in 172 patients. All met the criteria of a compression test of 10 to 25 kg/cm(2). The mean age was 17.3 years, and 22.7% had a positive family history of a congenital chest wall deformity. Symmetric and asymmetric deformities were treated. During our study period, we designed 4 different bar configurations and their related stabilizers. All patients are assessed every 3 to 6 months. After 2 to 3 years of follow-up, the bar and the stabilizers are removed. Results. Of 172 patients, 97.1% tolerated the procedure very well. The operation was a mean length 76.6 minutes. Average blood loss was 40 mL. Mean hospital length of stay was 3.7 days. Complications included pneumothorax, wire breakdown/rib cut, wound infection, severe pain, skin hyperpigmentation, nickel allergy, and overcorrection leading to excavatum. Patients returned to routine activity in 10 to 14 days. With a mean follow-up of 29.8 months in bar removal patients, 130 of 172 (93.8%) reported excellent results. Conclusions. Minimally invasive repair of pectus carinatum with the technically modified fourth-generation bar and its securing system has advantages of low morbidity, short hospital stay, and excellent cosmetic results, even in asymmetric cases. (C) 2018 by The Society of Thoracic SurgeonsPublication Metadata only Quality of life before and after pulmonary endarterectomy inchronic thromboembolic pulmonary hypertension(2012-06-10) YILDIZELİ, BEDRETTİN; ERMERAK, NEZİH ONUR; BOSTANCI, KORKUT; YILDIZELİ B., ELDEM B., ERMERAK N. O., ÇIRAN E., ÖZALPER M. H., İssaka A., BİLGİ Z., BOSTANCI K., BATIREL H. F., SUNAR H., et al.Publication Open Access Refractory invasive aspergillosis controlled with posaconazole and pulmonary surgery in a patient with chronic granulomatous disease: case report(BIOMED CENTRAL LTD, 2014-12) KEPENEKLİ KADAYİFCİ, EDA; Kepenekli, Eda; Soysal, Ahmet; Kuzdan, Canan; Ermerak, Nezih Onur; Yuksel, Mustafa; Bakir, MustafaInvasive aspergillosis is an important cause of morbidity and mortality in immunocompromised patients. Among primary immunodefiencies, chronic granulomatous disease (CGD) has the highest prevalence of invasive fungal diseases. Voriconazole is recommended for the primary treatment of invasive aspergillosis in most patients. In patients whose aspergillosis is refractory to voriconazole, therapeutic options include changing class of antifungal, for example using an amphotericin B formulation, an echinocandin, combination therapy, or further use of azoles. Posaconazole is a triazole derivative which is effective in Aspergillosis prophylaxis and treatment. Rarely, surgical therapy may be needed in some patients. Lesions those are contiguous with the great vessels or the pericardium, single cavitary lesion that cause hemoptysis, lesions invading the chest wall, aspergillosis that involves the skin and the bone are the indications for surgical therapy. Chronic granulomatous disease (CGD) is an inherited immundeficiency caused by defects in the phagocyte nicotinamide adenine dinucleotidephosphate (NADPH) oxidase complex which is mainstay of killing microorganisms. CGD is characterized by recurrent life-threatening bacterial and fungal infections and by abnormally exuberant inflammatory responses leading to granuloma formation, such as granulomatous enteritis, genitourinary obstruction, and wound dehiscence. The diagnosis is made by neutrophil function testing and the genotyping. Herein, we present a case with CGD who had invasive pulmonary aspergillosis refractory to voriconazole and liposomal amphotericine B combination therapy that was controlled with posaconazole treatment and pulmonary surgery.Publication Open Access Total Rib Resection Via Uniportal Thoracoscopic Approach(2018-10) ERMERAK, NEZİH ONUR; Ocakcıoglu, Ilhan; Ermerak, Nezih Onur; Yuksel, MustafaPublication Metadata only Development of a minimally invasive pectus carinatum bar(2015-05-31) LAÇİN, TUNÇ; ERMERAK, NEZİH ONUR; BOSTANCI, KORKUT; YÜKSEL M., LAÇİN T., ERMERAK N. O., ÇETİNKAYA Ç., BOSTANCI K.
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