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DURMUŞ KOCAASLAN, FATMA NİHAL

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DURMUŞ KOCAASLAN

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FATMA NİHAL

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Subject: Basal cell carcinoma ×

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    PublicationOpen Access
    Evaluation of residual tumors and recurrence rates of malignant melanoma and non-melanoma skin cancer of head and neck region
    (MARMARA UNIV, FAC MEDICINE, 2019-10-31) SAÇAK, BÜLENT; Durmus Kocaaslan, Fatma Nihal; Alakus, Ali Conor; Sacak, Bulent; Celebiler, Ozhan
    Objective: In this study, we aimed to evaluate residual tumors and recurrence rates of malignant melanoma (MM) and a nonmelanoma skin cancer of (NMSC) head and neck region. Patients and Methods: Medical data of a total of 398 lesions of 323 patients who underwent surgical excision for a basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma (MM) were retrospectively analyzed. All patients were classified according to age, sex, location of the tumor, histopathological diagnosis, lesion diameter, excision diameter, surgical margin status, and residual lesions and recurrence rates. Results: There were 244 lesions (61.3%) in 189 males and 154 lesions (38.7%) in 134 females. The most common type of skin cancer was BCC in 268 lesions (67%), followed by SCC in 122 (31%), and MM in eight (2%), respectively. Recurrence was seen in 3% of the NMSC cases and in 25% of the MM cases. There was a statistically significant correlation between the histopathological diagnosis and recurrence rates. Compared to NMSC, MM cases had a higher risk for recurrence (p=0.029). Conclusion: Our study results suggest that recurrence is associated with the localization and type of the tumor, but not with the age or sex of the patient.
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    Margin-Controlled, Staged Surgical Excision in the Treatment of High-Risk Basal Cell Carcinomas of the Head and Neck Region
    (SAGE PUBLICATIONS INC, 2019) SALMAN, ANDAÇ; Ucar, Ayse Nigar Durmus; Kocaaslan, Fatma Nihal Durmus; Salman, Andac; Demirkesen, Cuyan; Bayram, Filiz Erdem; Bayramicli, Mehmet
    Background: The most common skin cancer is basal cell carcinoma (BCC), and the gold-standard treatment for high-risk tumours is Mohs surgery. However, alternative methods are needed for high-risk tumours in countries where the performance rate of Mohs surgery is low. Objectives: The objective of this article is to investigate the feasibility, efficacy, and safety of margin-controlled, staged surgical excision (MCSSE) in high-risk tumours as a possible treatment alternative. Methods: A retrospective cohort study, including patients diagnosed with high-risk BCC in the head and neck region and treated with MCSSE between 2003 and 2010, was conducted. Results: During the study period 50 tumours in 47 patients were treated, with low adverse event rates and high patient satisfaction rates. Of the 50 tumours, 1 recurred at the 12-month follow-up. Conclusions: Despite the small sample size and relatively short follow-up period, the present study shows that MCSSE might be a feasible alternative for the treatment of high-risk BCCs in institutions where Mohs surgery is not performed. Future studies on long-term recurrence rates are needed.