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An eco-friendly process to extract hydroxyapatite from sheep bones for regenerative medicine: Structural, morphologic and electrical studies

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dc.contributor.authorGÜNDÜZ, OĞUZHAN
dc.contributor.authorOKTAR, FAİK NÜZHET
dc.contributor.authorsGavinho S. R., Bozdag M., KALKANDELEN C., Regadas J. S., Jakka S. K., GÜNDÜZ O., OKTAR F. N., Graça M. P. F.
dc.date.accessioned2023-06-12T10:30:54Z
dc.date.available2023-06-12T10:30:54Z
dc.date.issued2023-05-01
dc.description.abstractHydroxyapatite (HA) promotes excellent bone regeneration in bone-tissue engineering, due to its similarity to bone mineral and its ability to connect to living tissues. These factors promote the osteointegration process. This process can be enhanced by the presence of electrical charges, stored in the HA. Furthermore, several ions can be added to the HA structure to promote specific biological responses, such as magnesium ions. The main objective of this work was to extract hydroxyapatite from sheep femur bones and to study their structural and electrical properties by adding different amounts of magnesium oxide. The thermal and structural characterizations were performed using DTA, XRD, density, Raman spectroscopy and FTIR analysis. The morphology was studied using SEM, and the electrical measurements were registered as a function of frequency and temperature. Results show that: (i) an increase of MgO amount indicates that the solubility of MgO is below 5%wt for heat treatments at 600 °C; (ii) the rise of MgO content increases the capacity for electrical charge storage; (iii) sheep hydroxyapatite presents itself as a natural source of hydroxyapatite, environmentally sustainable and low cost, and promising for applications in regenerative medicine.
dc.identifier.citationGavinho S. R., Bozdag M., KALKANDELEN C., Regadas J. S., Jakka S. K., GÜNDÜZ O., OKTAR F. N., Graça M. P. F., "An Eco-Friendly Process to Extract Hydroxyapatite from Sheep Bones for Regenerative Medicine: Structural, Morphologic and Electrical Studies", Journal of Functional Biomaterials, cilt.14, sa.5, 2023
dc.identifier.doi10.3390/jfb14050279
dc.identifier.issn2079-4983
dc.identifier.issue5
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85160240376&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/290176
dc.identifier.volume14
dc.language.isoeng
dc.relation.ispartofJournal of Functional Biomaterials
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBiyomedikal Mühendisliği
dc.subjectMühendislik ve Teknoloji
dc.subjectBiomedical Engineering
dc.subjectEngineering and Technology
dc.subjectMühendislik, Bilişim ve Teknoloji (ENG)
dc.subjectMühendislik
dc.subjectMalzeme Bilimi
dc.subjectMALZEME BİLİMİ, BİYOMATERYAL
dc.subjectMÜHENDİSLİK, BİYOMEDİKAL
dc.subjectEngineering, Computing & Technology (ENG)
dc.subjectENGINEERING
dc.subjectMATERIALS SCIENCE
dc.subjectMATERIALS SCIENCE, BIOMATERIALS
dc.subjectENGINEERING, BIOMEDICAL
dc.subjectBiyomalzemeler
dc.subjectFizik Bilimleri
dc.subjectBiyomedikal mühendisliği
dc.subjectBiomaterials
dc.subjectPhysical Sciences
dc.subjectbiomaterials
dc.subjectbone regeneration
dc.subjecteco-friendly
dc.subjectelectrical properties
dc.subjectmagnesium oxide
dc.subjectnatural hydroxyapatite
dc.titleAn eco-friendly process to extract hydroxyapatite from sheep bones for regenerative medicine: Structural, morphologic and electrical studies
dc.typearticle
dspace.entity.typePublication
local.avesis.iddc79f29e-7e7c-4045-beca-dee6b680d272
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublicationf11e8073-bf2f-485f-9bdf-5b3a2a0bdc1f
relation.isAuthorOfPublication5ba0a0e0-ebae-43a6-855c-0aabb90021f4
relation.isAuthorOfPublication.latestForDiscoveryf11e8073-bf2f-485f-9bdf-5b3a2a0bdc1f

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