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Distribution and drug resistance of pathogens isolated from patients with hematological malignancies in three-year period

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dc.contributor.authorAKSU, MEHMET BURAK
dc.contributor.authorsArabacı Ç., Aksu M. B.
dc.date.accessioned2022-12-20T06:40:58Z
dc.date.available2022-12-20T06:40:58Z
dc.date.issued2022-09-01
dc.description.abstractObjective: This study aimed to retrospectively analyze the 3-year findings of bacterial and fungal pathogens isolated from infections in patients with hematological malignancies.Methods: A retrospective analysis of 158 patients with hematological malignancies treated between January 2015 and December 2017 in Okmeydanı Training and Research Hospital, Istanbul, Turkey. A total of 3374 non-consecutive blood samples (n=1954) from 158 patients, urine samples (n=1024), wound swabs (n=94), respiratory samples (n=87), and other samples (CSF, body fluids, etc.) (n=215) were collected. Results: Pathogen growth was detected in 6% (203/3374) of the samples. The most frequently isolated pathogens are coagulase-negative staphylococci (CNS, 20%), E. coli (19%), Klebsiella sp. (17%), and yeasts (16%), followed by Pseudomonas sp., Acinetobacter sp. and Enterococcus sp. (7%, 6%, and 6%, respectively). Candida species were dominant in fungal isolates (26/32; 81.2%). The most commonly detected antibiotic resistance patterns and organisms are carbapenem-resistant Acinetobacter sp. (92%), methicillin-resistant CNS (83%), carbapenem-resistant Klebsiella sp. (65%), MRSA (57%), and vancomycin-resistant Enterococci (VRE, 42%). Conclusion: Bloodstream infections accounted for more than half of all infection episodes. Periodic examination of the clinical and microbiological profiles of infections developing in patients with malignancy is essential for successful treatment management.
dc.identifier.citationArabacı Ç., Aksu M. B. , "Distribution and drug resistance of pathogens isolated from patients with hematological malignancies in three-year period", The Injector, cilt.1, sa.2, ss.47-51, 2022
dc.identifier.endpage51
dc.identifier.issue2
dc.identifier.startpage47
dc.identifier.urihttps://www.injectormedicaljournal.com/index.php/theinjector/article/view/11
dc.identifier.urihttps://hdl.handle.net/11424/283758
dc.identifier.volume1
dc.language.isoeng
dc.relation.ispartofThe Injector
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectMikrobiyoloji ve Klinik Mikrobiyoloji
dc.subjectTıbbi Mikrobiyoloji
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectMedicine
dc.subjectMicrobiology and Clinical Microbiology
dc.subjectMedical Microbiology
dc.subjectHealth Sciences
dc.subjectFundamental Medical Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectKlinik Tıp
dc.subjectMikrobiyoloji
dc.subjectTIP, GENEL & DAHİLİ
dc.subjectMİKROBİYOLOJİ
dc.subjectClinical Medicine (MED)
dc.subjectLife Sciences (LIFE)
dc.subjectCLINICAL MEDICINE
dc.subjectMICROBIOLOGY
dc.subjectMEDICINE, GENERAL & INTERNAL
dc.subjectGenel Sağlık Meslekleri
dc.subjectPatofizyoloji
dc.subjectTemel Bilgi ve Beceriler
dc.subjectDeğerlendirme ve Teşhis
dc.subjectMikrobiyoloji (tıbbi)
dc.subjectDahiliye
dc.subjectAile Sağlığı
dc.subjectTıp (çeşitli)
dc.subjectGenel Tıp
dc.subjectİmmünoloji ve Mikrobiyoloji (çeşitli)
dc.subjectYaşam Bilimleri
dc.subjectGeneral Health Professions
dc.subjectPathophysiology
dc.subjectFundamentals and Skills
dc.subjectAssessment and Diagnosis
dc.subjectMicrobiology (medical)
dc.subjectInternal Medicine
dc.subjectFamily Practice
dc.subjectMedicine (miscellaneous)
dc.subjectGeneral Medicine
dc.subjectMicrobiology
dc.subjectImmunology and Microbiology (miscellaneous)
dc.subjectLife Sciences
dc.titleDistribution and drug resistance of pathogens isolated from patients with hematological malignancies in three-year period
dc.typearticle
dspace.entity.typePublication
local.avesis.id7e514580-1743-4e34-b0c5-c722b4c4ff0e
relation.isAuthorOfPublicationf7de5699-7a5c-4496-93cf-d8daba79da4f
relation.isAuthorOfPublication.latestForDiscoveryf7de5699-7a5c-4496-93cf-d8daba79da4f

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