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Diagnostic utility of the Covichem score in predicting COVID-19 disease

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dc.contributor.authorÖZPOLAT, ÇİĞDEM
dc.contributor.authorALTUNBAŞ, ERHAN
dc.contributor.authorsÖZPOLAT Ç., Altunbas E.
dc.date.accessioned2022-12-27T08:39:13Z
dc.date.available2022-12-27T08:39:13Z
dc.date.issued2022-10-01
dc.description.abstract© 2022 Elsevier Inc.Background: Identifying which patients with COVİD-19 have a high risk of severe illness is essential to optimizing management and resource utilization strategies. Objectives: The aim of this study was to externally validate the diagnostic utility of the Covichem score for predicting COVID-19 disease severity, and secondarily to evaluate its utility in predicting intensive care unit (ICU) admission, and in-hospital mortality. Methods: All consecutive COVID-19 patients who presented to the emergency department (ED) were included, and patients\" demographic data, comorbidities, vital signs, oxygen requirement, and laboratory results were recorded. We calculated patients\" Covichem scores and estimates (using a threshold of 0.5) and evaluated the utility of the Covichem score for predicting disease severity, ICU admission, and mortality. Results: The median Covichem score was significantly higher for patients with severe illness (Covichem score: 0.170, IQR: 0.298, n = 300 vs. Covichem score: 0.026, IQR: 0.065, n: 191; p < 0.001). Based on their Covichem scores, 12.4% (61/491) of the patients were predicted to experience severe illness (threshold: 0.5), the accuracy of the Covichem score was poor, as the area under curve (AUC) was 48.5% (18.1% sensitivity and 93.8% specificity). When we calculated a new ideal threshold, the AUC reached 82%, but the sensitivity was 79.9% and the specificity was 71.2%. Conclusion: In this external validation of the Covichem score, we found that it performed worse than in the original derivation and validation study, even with the assistance of a new cutoff.
dc.identifier.citationÖZPOLAT Ç., Altunbas E., "Diagnostic utility of the Covichem score in predicting COVID-19 disease", American Journal of Emergency Medicine, cilt.60, ss.50-56, 2022
dc.identifier.doi10.1016/j.ajem.2022.07.025
dc.identifier.endpage56
dc.identifier.issn0735-6757
dc.identifier.startpage50
dc.identifier.urihttps://hdl.handle.net/11424/284215
dc.identifier.volume60
dc.language.isoeng
dc.relation.ispartofAmerican Journal of Emergency Medicine
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectTıp
dc.subjectCerrahi Tıp Bilimleri
dc.subjectAcil Tıp
dc.subjectSağlık Bilimleri
dc.subjectMedicine
dc.subjectSurgery Medicine Sciences
dc.subjectEmergency Medicine
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectACİL TIP
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectEMERGENCY MEDICINE
dc.subjectCovichem score
dc.subjectCOVID-19
dc.subjectSeverity
dc.subjectPrognosis
dc.titleDiagnostic utility of the Covichem score in predicting COVID-19 disease
dc.typearticle
dspace.entity.typePublication
local.avesis.idbc7ade5e-570c-4588-ad31-81e2d4307116
local.indexed.atWOS
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublication49a44509-1a25-4a10-bf29-147a09795c78
relation.isAuthorOfPublicationde113ce1-8562-4c7e-bc5c-9f8887d163d7
relation.isAuthorOfPublication.latestForDiscovery49a44509-1a25-4a10-bf29-147a09795c78

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