Publication: Late breaking abstract - association with changes in pulmonary artery diameters and outcomes before, during and after covid-19 hospitalization: Retrospective study
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2023-09-09
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Abstract
Background:Enlarged main pulmonary artery diameter(MPAD)is a predictor of increased mortality in COVID-19. However, the changes in MPAD before and after COVID-19 remain obscure.Aim:To find the factors that affect changes in MPAD during COVID-19 and postCOVID-19 period; the relationship between the MPAD, thromboinflammation and radiological scores(RS), clinical outcomes in patients.Methods:This study is retrospective and single centered. Among the 3264 patients hospitalized followed at least 3 months between March 2020 and January 2023, 66 patients with previous and subsequent chest CT were included.3 measurements of MPAD before, during and after COVID-19, WHO Score, RS and laboratory variables have been recorded from the hospital information system. ICU admission and mortality as clinical outcomes and factors that affect MPAD evaluated by uni-and multivariate analysis.Results:MPAD of patients had increased during COVID-19 and showed tendency to decrease but persisted to increase after(p<0.001,p>0.05). Low Lymphocyte/CRP, high D-dimer and ICU admission had significantly increased risk for remained enlarged MPAD postCOVID-19(OR=10.37,p<0.01;OR=1.1, p<0.01,OR=5.14, p<0.01). Patient with higher postMPAD had significant correlation with increased WHO Score and RS after COVID-19(both R=0.3,p<0.05)but not mortality.Conclusion:MPAD significantly increases during COVID-19 and persisted after that. Apart from that, patients who admitted to ICU, had high d-dimer and inflammation markers in COVID-19,had increased risk for enlarged postMPAD that correlated WHO-Score and radiological scores in post-COVID-19. Especially these patients, can be followed carefully after the infection.
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Tıp, Dahili Tıp Bilimleri, Göğüs Hastalıkları ve Allerji, Sağlık Bilimleri, Medicine, Internal Medicine Sciences, Chest Diseases and Allergy, Health Sciences, Klinik Tıp (MED), Klinik Tıp, SOLUNUM SİSTEMİ, TIP, GENEL & DAHİLİ, Clinical Medicine (MED), CLINICAL MEDICINE, RESPIRATORY SYSTEM, MEDICINE, GENERAL & INTERNAL, Solunum Bakımı, Genel Sağlık Meslekleri, Patofizyoloji, Temel Bilgi ve Beceriler, Değerlendirme ve Teşhis, Akciğer ve Solunum Tıbbı, Dahiliye, Aile Sağlığı, Tıp (çeşitli), Genel Tıp, Respiratory Care, General Health Professions, Pathophysiology, Fundamentals and Skills, Assessment and Diagnosis, Pulmonary and Respiratory Medicine, Internal Medicine, Family Practice, Medicine (miscellaneous), General Medicine
Citation
Selcuk A., Kocakaya D., Olgun Yildizeli Ş., Karakurt S., \"Late Breaking Abstract - Association with changes in pulmonary artery diameters and outcomes before, during and after COVID-19 hospitalization:Retrospective Study\", ERS International Congress 2023 abstracts, Milan, İtalya, 9 - 13 Eylül 2023, ss.1