Publication:
An outbreak investigation of Burkholderia cepacia infections related with contaminated chlorhexidine mouthwash solution in a tertiary care center in Turkey

Simple item page
dc.contributor.authorGÜL, FETHİ
dc.contributor.authorsBilgin, Huseyin; Gelmez, Gulsen Altinkanat; Bayrakdar, Fatma; Sayin, Elvan; Gul, Fethi; Pazar, Nazli; Culha, Gulcan; Yildiz, Serap Suzuk; Cinel, Ismail; Korten, Volkan
dc.date.accessioned2022-03-14T09:55:05Z
dc.date.available2022-03-14T09:55:05Z
dc.date.issued2021-12
dc.description.abstractBackground: We report a nosocomial outbreak caused by Burkholderia cepacia that occurred among six patients admitted in the medical and surgical intensive care unit between 04 March 2019 and 02 April 2019 in Istanbul, Turkey. Methods: The outbreak investigation was launched on 11 March 2019 five days after the detection of B. cepacia in four different patients. We defined potential reservoirs and started environmental screening. We sampled the liquid solutions used in patient care activities. Pulse-field gel electrophoresis (PFGE) was performed to determine the genetic relatedness of environmental and patient samples. Results: Burkholderia cepacia was isolated in tracheal aspiration cultures of six patients. Three out of six patients developed healthcare-associated pneumoniae due to B. cepacia. Environmental cultures in the ICUs revealed B. cepacia growth in 2% chlorhexidine-gluconate mouthwash solution that been used in the colonized patients as well as in samples obtained from the unused products. PFGE revealed the patient and a specific batch of chlorhexidine mouthwash solution samples had a 96% similarity. Conclusion: Contamination of medical solutions used in critical patient care could cause outbreaks and should be detected early by infection control teams.
dc.identifier.doi10.1186/s13756-021-01004-8
dc.identifier.issn2047-2994
dc.identifier.pubmed34629114
dc.identifier.urihttps://hdl.handle.net/11424/243645
dc.identifier.wosWOS:000705388300001
dc.language.isoeng
dc.publisherBMC
dc.relation.ispartofANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBurkholderia cepacia
dc.subjectOutbreak
dc.subjectIntensive care unit
dc.subjectChlorhexidine mouthwash
dc.subjectVentilator-associated-pneumoniae
dc.subjectHealthcare associated infection
dc.subjectContamination
dc.subjectOutbreak investigation
dc.subjectCRITERIA
dc.subjectCOMPLEX
dc.titleAn outbreak investigation of Burkholderia cepacia infections related with contaminated chlorhexidine mouthwash solution in a tertiary care center in Turkey
dc.typearticle
dspace.entity.typePublication
local.avesis.ide5a87c4f-e6e9-4be4-aff7-497815a33d8e
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber143
local.journal.numberofpages6
oaire.citation.issue1
oaire.citation.titleANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
oaire.citation.volume10
relation.isAuthorOfPublication907a6efd-2877-4832-b6a2-d87a28e52165
relation.isAuthorOfPublication.latestForDiscovery907a6efd-2877-4832-b6a2-d87a28e52165

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Bilgin et al. - 2021 - An outbreak investigation of Burkholderia cepacia .pdf
Size:
1.07 MB
Format:
Adobe Portable Document Format
Download

Collections

Research Outputs