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Surgical outcomes of patients with non-small cell lung cancer following neoadjuvant treatment

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dc.contributor.authorERMERAK, NEZİH ONUR
dc.contributor.authorsOcakcioglu, Ilhan; Alpay, Levent; Ermerak, Nezih Onur; Kiral, Hakan; Tezel, Cagatay; Baysungur, Volkan; Yalcinkaya, Irfan
dc.date.accessioned2022-03-14T09:04:29Z
dc.date.available2022-03-14T09:04:29Z
dc.date.issued2018-10-31
dc.description.abstractObjective: Although, anatomical resection of non-small cell lung cancer (NSCLC) following neoadjuvant therapy is still controversial, it is a widely accepted approach for thoracic surgery practice. The aim of this study is to briefly evaluate clinical results, long term survival, and factors affecting survival of the patients with locally advanced NSCLC, pancoast tumour and lung cancer with solitary brain metastasis, who have been operated at our institution following neoadjuvant therapy. Materials and Method: Between March 2006 and March 2012, 70 patients with NSCLC diagnosis who underwent anatomic pulmonary resection following neoadjuvant therapy were included in the study. Results: A three year survival (39%) and a 5-year survival (29%) were 16 +/- 6.8 and 37 +/- 9.89 months, respectively. The mean survival was found to be 37.15 +/- 3.06 months. When survival rate was evaluated according to localization of tumor, it was lower in central and left upper lobe tumors compared to other anatomical localizations (P=0.042). The mean 5-year survival times were 50.00 +/- 5.65 months in stage 0 patients, 35.39 +/- 5.85 months in stage 1 patients, 37.40 +/- 6.89 months in stage 2 patients and 21.44 +/- 3.10 months in stage 3 patients. Conclusion: We can achieve significant survival results by the anatomical pulmonary resection following neoadjuvant therapy.
dc.identifier.doi10.5472/marumj.474165
dc.identifier.issn1309-9469
dc.identifier.urihttps://hdl.handle.net/11424/242395
dc.identifier.wosWOS:000448609100002
dc.language.isoeng
dc.publisherMARMARA UNIV, FAC MEDICINE
dc.relation.ispartofMARMARA MEDICAL JOURNAL
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNon-small cell lung cancer
dc.subjectNeoadjuvant therapy
dc.subjectChemotherapy
dc.subjectRadiotherapy
dc.subjectSurgery
dc.subjectINDUCTION CHEMOTHERAPY
dc.subjectSTAGE
dc.subjectIIIA
dc.subjectSURVIVAL
dc.subjectTHERAPY
dc.subjectPNEUMONECTOMY
dc.subjectMORBIDITY
dc.subjectMORTALITY
dc.subjectRESECTION
dc.subjectSURGERY
dc.titleSurgical outcomes of patients with non-small cell lung cancer following neoadjuvant treatment
dc.typearticle
dspace.entity.typePublication
local.avesis.ide4b1fea1-7517-471b-a3e2-fcee8e2f18cd
local.import.packageSS16
local.indexed.atWOS
local.indexed.atTRDIZIN
local.journal.numberofpages7
oaire.citation.endPage107
oaire.citation.issue3
oaire.citation.startPage101
oaire.citation.titleMARMARA MEDICAL JOURNAL
oaire.citation.volume31
relation.isAuthorOfPublicationa222ea0d-ad32-4e7e-b052-db1d35be2d78
relation.isAuthorOfPublication.latestForDiscoverya222ea0d-ad32-4e7e-b052-db1d35be2d78

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