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The effect of 2 different distraction-compression models on new bone generation

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dc.contributor.authorÇELEBİLER, ÖZHAN BEKİR
dc.contributor.authorsÖzgl S., Akdeniz Z.D., Çelebiler Ö., Alcan T., Sav A.
dc.date.accessioned2022-03-15T02:09:34Z
dc.date.available2022-03-15T02:09:34Z
dc.date.issued2012
dc.description.abstractTo compare the stimulating effect of distraction and 2 different distraction-compression models on maturation of new bone during healing. Thirty adult Sprague-Dawley rats underwent unilateral mandibular osteotomy. The animals were divided into 3 groups. A unidirectional external distraction device was fixed to the mandible. A total of 4 mm of distraction was planned in all groups. After a latency period of 3 days, 0.2 mm of distraction was performed twice a day for 10 days in the distraction group. In the intermittent distraction-compression group, 0.2 mm of distraction was performed twice a day for 3 days, followed by 0.2 mm of compression twice a day for 1 day. In the overdistraction-compression group, 0.2 mm of distraction was performed twice a day for 14 days, followed by 0.2 mm of compression twice a day for 4 days. After a consolidation period of 6 weeks in all groups, animals were killed for macroscopic, microscopic, and radiologic evaluation. Radiologic evaluation proved that more mature bone generation occurred in the groups in which compression was added to distraction. The number of osteoblasts in the intermittent distraction-compression group was significantly higher than that in the distraction group and overdistraction-compression group (P < .001). The highest number of vessels was found in the intermittent distraction-compression group (17.7 ± 6.4) (P < .001). The intermittent distraction- compression model was found to generate greater new bone compared with distraction alone. In clinical applications, to increase the quality of the bone and to shorten the consolidation period, compression can be applied during distraction. © 2012 American Association of Oral and Maxillofacial Surgeons.
dc.identifier.doi10.1016/j.joms.2012.05.022
dc.identifier.issn2782391
dc.identifier.pubmed22907114
dc.identifier.urihttps://hdl.handle.net/11424/247191
dc.language.isoeng
dc.relation.ispartofJournal of Oral and Maxillofacial Surgery
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.titleThe effect of 2 different distraction-compression models on new bone generation
dc.typearticle
dspace.entity.typePublication
local.avesis.id65e2fd7c-dfa4-4d4d-92ba-4d00be44c71b
local.import.packageSS21
local.import.sourceScopus
local.indexed.atSCOPUS
local.indexed.atPUBMED
oaire.citation.endPagee499
oaire.citation.issue9
oaire.citation.startPagee490
oaire.citation.titleJournal of Oral and Maxillofacial Surgery
oaire.citation.volume70
relation.isAuthorOfPublication52ba4b8c-c2cd-4ec3-9471-d6a2386f937e
relation.isAuthorOfPublication.latestForDiscovery52ba4b8c-c2cd-4ec3-9471-d6a2386f937e

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