Publication: Production of the novel fibrous structure of poly(epsilon-caprolactone)/tri-calcium phosphate/hexagonal boron nitride composites for bone tissue engineering
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Date
2018
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Publisher
AUSTRALIAN CERAMIC SOCIETY
Abstract
Nanofibrous composites of the poly(epsilon-caprolactone) (PCL), tricalcium phosphate (TCP), and hexagonal boron nitride (h-BN) with different compositions were manufactured by using an economical and non-complicated method called electrospinning. Produced fibrous structures showed no bead formation and had a clean surface. Characterization of the composites showed that particles were successfully mixed with polymer phase. High cell activity of SaOS-2 cells on the composites was observed with SEM images. In addition, fibrous scaffolds are biocompatible with human bone tissue and are highly degradable.
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Keywords
Biopolymers, Biofibers, Biomaterials, Poly(epsilon-caprolactone), Composites, POLYCAPROLACTONE, SCAFFOLDS, FABRICATION