Publication:
A single-center multidisciplinary study analyzing thyroid nodule risk stratification by comparing the thyroid imaging reporting and data system (TI-RADS) and American thyroid association (ATA) risk of malignancy for thyroid nodules

Simple item page
dc.contributor.authorASYA, ORHAN
dc.contributor.authorYUMUŞAKHUYLU, ALİ CEMAL
dc.contributor.authorENVER, NECATİ
dc.contributor.authorİNCAZ, SEFA
dc.contributor.authorGÜNDOĞMUŞ, CEMAL AYDIN
dc.contributor.authorERGELEN, RABİA
dc.contributor.authorBAĞCI ÇULÇİ, PELİN
dc.contributor.authorOYSU, ÇAĞATAY
dc.contributor.authorsASYA O., YUMUŞAKHUYLU A. C. , ENVER N., Gündoğdu Y., Abuzaid G., İNCAZ S., GÜNDOĞMUŞ C. A. , ERGELEN R., Bağcı P., OYSU Ç.
dc.date.accessioned2022-12-26T12:42:05Z
dc.date.available2022-12-26T12:42:05Z
dc.date.issued2022-01-01
dc.description.abstract© 2022 Elsevier LtdObjectives: The thyroid imaging reporting and data system (TI-RADS) and 2015 American Thyroid Association (ATA) guidelines are two well-known risk stratification systems for classifying thyroid nodules based on cancer risk. This study aims to evaluate the diagnostic efficacy of these two systems in predicting malignancy in patients undergoing thyroid surgery. Methods: We studied data on 120 individuals who were scheduled to undergo surgery for benign or malignant nodular diseases of the thyroid gland between October 2017 and October 2019. The TI-RADS category and ultrasound pattern based on ATA guidelines were assigned to dominant thyroid nodule categories by two experienced radiologists blinded to patients’ previous thyroid ultrasonography and fine-needle aspiration biopsy results. A pathologist with experience in thyroid diseases blinded to patients’ sonographic and clinical data reviewed the thyroidectomy specimens. Results: A total of 120 patients, 88 women and 32 men, were included in our study. Final histopathological results were as follows: 50% (n=60) papillary thyroid carcinoma, 36.6% (n=44) benign nodular thyroid diseases, 4.1% (n=5) follicular adenoma, 2.5% (n=3) hurtle cell adenoma, 1.7% (n=2) follicular thyroid carcinoma, 1.7% (n=2) medullary thyroid carcinoma, 1.7% (n=2) hurtle cell carcinoma, and 1.7% (n=2) follicular tumor of uncertain malignancy potential. The sensitivity, specificity, positive predictive value, and negative predictive value for TI-RADS were 80%, 56%, 72%, and 67%, respectively, and that for ATA were 80%, 64%, 76%, and 69%, respectively. Conclusion: The TI-RADS and ATA showed similar rates of sensitivity, specificity, NPV, and PPV. Our observed risk of malignancy was higher than expected for the ACR TI-RADS 3–5 categories and the very low, low, and intermediate suspicion risk strata in the ATA guidelines. We found no difference between observed and expected malignancy risk for the ACR TI-RADS 2’s and ATA\"s high suspicion categories.
dc.identifier.citationASYA O., YUMUŞAKHUYLU A. C. , ENVER N., Gündoğdu Y., Abuzaid G., İNCAZ S., GÜNDOĞMUŞ C. A. , ERGELEN R., Bağcı P., OYSU Ç., "A single-center multidisciplinary study analyzing thyroid nodule risk stratification by comparing the thyroid imaging reporting and data system (TI-RADS) and American thyroid association (ATA) risk of malignancy for thyroid nodules", Auris Nasus Larynx, 2022
dc.identifier.doi10.1016/j.anl.2022.08.006
dc.identifier.issn0385-8146
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85137649521&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/284049
dc.language.isoeng
dc.relation.ispartofAuris Nasus Larynx
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectCerrahi Tıp Bilimleri
dc.subjectKulak Burun Boğaz
dc.subjectSağlık Bilimleri
dc.subjectMedicine
dc.subjectSurgery Medicine Sciences
dc.subjectOtolaryngology
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectCERRAHİ
dc.subjectKULAK BURUN BOĞAZ
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectSURGERY
dc.subjectOTORHINOLARYNGOLOGY
dc.subjectCerrahi
dc.subjectSurgery
dc.subjectOtorhinolaryngology
dc.subject2015 American thyroid association management guideline
dc.subjectThyroid imaging reporting and data system
dc.subjectThyroid nodule
dc.subjectUltrasound
dc.titleA single-center multidisciplinary study analyzing thyroid nodule risk stratification by comparing the thyroid imaging reporting and data system (TI-RADS) and American thyroid association (ATA) risk of malignancy for thyroid nodules
dc.typearticle
dspace.entity.typePublication
local.avesis.idad8b24bd-c628-4a89-a9e6-7f3ef3265043
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublication01d9ec05-50a4-4026-8d6b-d8994a0272b1
relation.isAuthorOfPublication2c8f9431-6c94-4fd6-ab90-3e56beb761ba
relation.isAuthorOfPublication47e0392d-e1ee-45d3-8f90-9dbccd94970b
relation.isAuthorOfPublicationced17fa4-f814-4097-a7a6-88cdbb8b0b1b
relation.isAuthorOfPublication2cb86747-2d35-46df-8529-3c9eecae9a8c
relation.isAuthorOfPublicationc03828a2-d733-457f-97f0-ae7d7420fbe0
relation.isAuthorOfPublication08d32d97-3eab-4e66-9cb5-3177601d83e9
relation.isAuthorOfPublicationec6e486e-15b1-4c25-910f-5f85ab2fbaf4
relation.isAuthorOfPublication.latestForDiscovery01d9ec05-50a4-4026-8d6b-d8994a0272b1

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
7.pdf
Size:
311.51 KB
Format:
Adobe Portable Document Format
Download

Collections

Research Outputs