SALMAN, ANDAÇDURMUŞ KOCAASLAN, FATMA NİHALBAYRAMİÇLİ, MEHMET NURİ ÜMİT2022-03-122022-03-1220191203-4754https://hdl.handle.net/11424/235716Background: The most common skin cancer is basal cell carcinoma (BCC), and the gold-standard treatment for high-risk tumours is Mohs surgery. However, alternative methods are needed for high-risk tumours in countries where the performance rate of Mohs surgery is low. Objectives: The objective of this article is to investigate the feasibility, efficacy, and safety of margin-controlled, staged surgical excision (MCSSE) in high-risk tumours as a possible treatment alternative. Methods: A retrospective cohort study, including patients diagnosed with high-risk BCC in the head and neck region and treated with MCSSE between 2003 and 2010, was conducted. Results: During the study period 50 tumours in 47 patients were treated, with low adverse event rates and high patient satisfaction rates. Of the 50 tumours, 1 recurred at the 12-month follow-up. Conclusions: Despite the small sample size and relatively short follow-up period, the present study shows that MCSSE might be a feasible alternative for the treatment of high-risk BCCs in institutions where Mohs surgery is not performed. Future studies on long-term recurrence rates are needed.enginfo:eu-repo/semantics/closedAccessBasal cell carcinomahigh riskmargin-controlledstaged surgical excisionMOHS SURGERYFOLLOW-UPSLOW MOHSarticleWOS:00046898550000310.1177/1203475418820868305564241615-7109