TAŞKIN, TURGUT2024-08-122024-08-122024-01-01Kekeç N., TAŞKIN T., AĞAR D. N., ÖZBEK ÇELİK B., KÜLTÜR Ş., SÜZGEÇ SELÇUK S., "Phytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activities", Journal of Research in Pharmacy, cilt.28, sa.3, ss.630-640, 20242630-6344https://avesis.marmara.edu.tr/api/publication/216b2bcf-68e8-41f0-a2d5-38767e0fcd23/filehttps://hdl.handle.net/11424/297537Helichrysum armenium subsp. armenium plant was extracted with the Soxhlet apparatus. The obtained extract was fractionated and, respectively, AHB (petroleum ether–60% ethanol-chloroform), AHC (ethanol-toluene), AHD (ethanol-chloroform), and AHE (ethanol-ethylacetate) extracts were obtained. Then, antimicrobial, antioxidant, and acetylcholinesterase activity studies were performed on these extracts. In this study, with the using the LC-HRMS method from the aerial parts of Helichrysum armenium subsp. armenium, the flavonoids: apigenin, apigenin 7-glucoside, apigenin 7-methylate, luteolin 7-glucoside, kaempferol, quercetin, quercitrin, (+)-trans taxifolin, (-)-epicatechin gallate, sinensetin, rutin, 3\"-o-methyl quercetin, hispidulin, chrysin, acacetin, genkwanin, chrysoeriol; the phenolic acids: chlorogenic acid, ascorbic acid, fumaric acid, caffeic acid, salicylic acid, caffeic acid phenethyl ester, emodin, vanilic acid; the alkaloid: caffeine and the saponoside; glycyrrhizic acid were obtained.enginfo:eu-repo/semantics/openAccessTemel Eczacılık BilimleriEczacılıkYaşam BilimleriSağlık BilimleriTemel BilimlerBasic Pharmaceutics SciencesPharmacology and TherapeuticsLife SciencesHealth SciencesNatural SciencesYaşam Bilimleri (LIFE)Farmakoloji ve ToksikolojiFARMAKOLOJİ VE ECZACILIKLife Sciences (LIFE)PHARMACOLOGY & TOXICOLOGYPHARMACOLOGY & PHARMACYGenel Farmakoloji, Toksikoloji ve EczacılıkFarmakoloji (tıbbi)General Pharmacology, Toxicology and PharmaceuticsPharmacology (medical)acetylcolinesteraseantimicrobialantioxidantHelichrysum armenium subsp. armeniumLC-HRMSphenolic compoundsPhytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activitiesarticle28363064010.29228/jrp.724