MUTLU, BÜLENT2023-05-292023-05-292022-07-01Bohbot Y., Habib G., Laroche C., Stohr E., Chirouze C., Hernandez-Meneses M., Melissopoulou M., Mutlu B., Scheggi V., Branco L., et al., "Characteristics, management, and outcomes of patients with left-sided infective endocarditis complicated by heart failure: a substudy of the ESC-EORP EURO-ENDO (European infective endocarditis) registry", EUROPEAN JOURNAL OF HEART FAILURE, cilt.24, ss.1253-1265, 20221388-9842https://pubmed.ncbi.nlm.nih.gov/35508915/https://hdl.handle.net/11424/289694Aims To evaluate the current management and survival of patients with left-sided infective endocarditis (IE) complicated by congestive heart failure (CHF) in the ESC-EORP European Endocarditis (EURO-ENDO) registry. Methods and results Among the 3116 patients enrolled in this prospective registry, 2449 (mean age: 60years, 69% male) with left-sided (native or prosthetic) IE were included in this study. Patients with CHF (n = 698, 28.5%) were older, with more comorbidity and more severe valvular damage (mitro-aortic involvement, vegetations >10 mm and severe regurgitation/new prosthesis dehiscence) than those without CHF (all p 10 mm, severe valvular regurgitation and/or new prosthetic dehiscence, perivalvular complication, and prosthetic IE (OR 0.22, 95% CI 0.12-0.38; p < 0.001) and in 1-year mortality (HR 0.29, 95% CI 0.20-0.41; p < 0.001). Conclusion Congestive heart failure is common in left-sided IE and is associated with older age, greater comorbidity, more advanced lesions, and markedly higher 30-day and 1-year mortality. Early surgery is strongly associated with lower mortality but is performed on only approximately half of patients with CHF, mainly because of a surgical risk considered prohibitive.enginfo:eu-repo/semantics/openAccessTıpSağlık BilimleriDahili Tıp BilimleriKardiyolojiMedicineHealth SciencesInternal Medicine SciencesCardiovascularKALP VE KALP DAMAR SİSTEMLERİKlinik TıpKlinik Tıp (MED)CARDIAC & CARDIOVASCULAR SYSTEMSCLINICAL MEDICINEClinical Medicine (MED)Kardiyoloji ve Kardiyovasküler TıpCardiology and Cardiovascular MedicineInfective endocarditisCongestive heart failureSurvivalOutcomeEarly surgeryEURO-ENDONATIVE VALVE ENDOCARDITISPROGNOSTIC-FACTORSMORTALITYSURGERYRISKPREDICTORSADULTSIMPACTDEATHInfective endocarditisCongestive heart failureSurvivalOutcomeEarly surgeryEURO-ENDOarticle241253126510.1002/ejhf.2525