YAVUZ, DİLEKÇERMAN, ERENÇELİKER ATABERK, HANDEERASLAN, MUHSİNŞAHİN, ÖZLEM2022-03-152022-03-15201316725123https://hdl.handle.net/11424/247315AIM: To investigate the potential association between serum sialic acid and diabetic retinopathy and its several grades. METHODS: We studied the level of serum sialic acid in 70 patients. Thirty control vs 40 type 1 diabetics and with different levels of diabetic retinopathy as well. RESULTS: We found higher levels of serum sialic acid level in diabetics compared to control subjects (95.95±9.5 vs 45.05±19.91 mmoL/L, P=0.0001). We also observed a progressive rise in its concentration as the level of diabetic retinopathy increased (P<0.05) but the correlation was weak. Serum sialic acid level correlated positively with blood glucose level (r=0.67, P=0.0001). CONCLUSION: Increase in serum sialic acid levels seems to be related to the stage of the retinopathy and may help us to determine the extent of retinopathy in type 1 diabetic patients. But we think that we need more detailed studies to get a more precise conclusion.enginfo:eu-repo/semantics/closedAccessDiabetesDiabetic retinopathyHbA1cSerumSialic acidIncreased serum sialic acid in diabetic retinopathy of type 1 diabetesarticle10.3980/j.issn.1672-5123.2013.10.02