Person: ÖZTÜRK ÖZENER, HAFİZE
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ÖZTÜRK ÖZENER
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HAFİZE
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Publication Metadata only Effect of topically applied hyaluronic acid on pain and palatal epithelial wound healing: An examiner-masked, randomized, controlled clinical trial(AMER ACAD PERIODONTOLOGY, 2018) DOĞAN, BAŞAK; Yildirim, Selin; Ozener, Hafize Ozturk; Dogan, Basak; Kuru, BaharBackground: This study aims to evaluate the effects of two different concentrations of topical hyaluronic acid (HA) on postoperative patient discomfort and wound healing of palatal donor sites after free gingival graft (FGG) surgery. Methods: Thirty-six patients requiring FGG were randomly assigned into three groups in an examiner-masked, randomized, controlled clinical trial. After harvesting palatal grafts, 0.2% and 0.8% HA gels were used in test groups 1 and 2, respectively. Gels were applied on donor sites and protected with periodontal dressing in the test groups, whereas the wound was covered only with periodontal dressing in the control group. On days 3, 7, 14, and 21, pain and burning sensation were recorded using a visual analog scale (VAS) as well as other parameters such as complete epithelization (CE) and color match on days 3, 7, 14, 21, and 42. Results: Test groups experienced less pain than the control group on days 3 and 7 (P < 0.001 and P < 0.001, respectively). Mean VAS score for burning sensation was higher in the control group on day 3 compared with test groups 1 and 2 (P = 0.03 and P = 0.02, respectively). CE in all patients was achieved on day 21 in both test groups, whereas it was achieved on day 42 in the control group. The test groups showed higher color match scores than the control group on days 21 (P < 0.001 and P < 0.001, respectively) and 42 (P = 0.004 and P = 0.002, respectively). Conclusion: Topical application of HA exhibits positive impact on postoperative pain and burning sensation, and accelerates palatal wound healing in terms of epithelization and color match.Publication Metadata only Oral squamous cell papilloma: a case report(AVES PRESS LTD, 2015) ÖZTÜRK ÖZENER, HAFİZE; Ozener, Hafize Ozturk; Kuru, Leyla; Kuru, BaharOral squamous cell papilloma (OSCP) is a benign proliferation of the stratified squamous epithelium, which results in a papillary or verrucous exophytic mass. OSCP is usually associated with human papilloma virus. Although any surface of the oral cavity can be affected, the sites of predilection for localization of the lesions include the tongue, lip and soft palate. In this report, treatment and histological findings of a local gingival enlargement at the vestibular side of the upper right central tooth of a 10 year-old systemically healthy girl are presented. The lesion was asymptomatic and had shown a slow growth. Solitary, exophytic lesion was clinically soft, pink-white in color and appeared as cauliflower. Dental and periodontal tissues were radiographically normal. One month after scaling and root planing, under local anesthesia the lesion was excised and this was followed by the use of Nd: YAG laser (1064 nm, 20 Hz, 3 W) to control bleeding, minimize pain and scarring in post-operative period, and provide sterilization. Macroscopic examination revealed that the lesion was 1.1x0.5x0.2 cm(3) in size, yellow in colour and had a rough surface, while histological examination showed multi-layer connective tissue underlying the squamous epithelium, numerous rete pegs and spinous cell proliferation at the papillary and OSCP was diagnosed. There was no evidence of viral cytopathic effect or malignancy of the lesion. No recurrence was observed during the 4-year follow-up period..Publication Open Access Different treatment approaches for the localized gingival overgrowths: Case series(2018-04) DOĞAN, BAŞAK; Ozener, Hafize Ozturk; Kundak, Kubra; Sipahi, Nimet Gul; Yetis, Ece; Dogan, BasakABSTRACT Localized gingival overgrowths belong to a common group of lesions designated as focal reactive overgrowths. They occur in response to chronic, low‑grade irritation caused by plaque or any other irritant. They have multifactorial etiopathology but exhibit similar clinical features with slight variations in patient complaints. Success of the lesions’ management depends on formation of healthy contours of the surgical area after excision of lesion and absence of a recurrence. The purpose of case series is to present 6 different cases of localized gingival overgrowths and their management with the following techniques: nonsurgical periodontal treatment, gingivectomy, flap surgery, free gingival graft, gingival unit, and connective tissue graft.Publication Open Access Evaluation of the Effectiveness of Esterified Hyaluronic Acid Fibers on Bone Regeneration in Rat Calvarial Defects(HINDAWI LTD, 2018-06-28) ÖZBEYLİ, DİLEK; Agrali, Omer B.; Yildirim, Selin; Ozener, Hafize O.; Kose, Kemal N.; Ozbeyli, Dilek; Soluk-Tekkesin, Merva; Kuru, LeylaHyaluronic acid (HA) constitutes one of the major components of the extracellular matrix domain in almost all mammals. The aim of this study was to evaluate the regenerative capacity of HA matrix in rat calvarial bone defects and compare with those of different combinations of resorbable collagen membrane (M) and bovine-derived xenograft (G). Twenty-four 3-month-old male Sprague-Dawley rats weighing 200-250 g were included. Control group was created by leaving one defect empty from 2 critical size defects with 5 mm diameter formed in the calvarial bones of 8 rats. In the same rats, the other defect was treated with HA matrix alone. One of the 2 defects formed in other 8 rats was treated with HA + G and the other with HA + M. One of the 2 defects formed in the remaining 8 rats was treated wilh G+M and the other with HA+G+M. The animals were sacrificed at 4 weeks. Histologic, histomorphometric, and immunohistochemical analyses were performed. Both HA matrix alone and its combinalions with G and M supported new bone formation (NBF). However, NBF was significantly greater in G+M and HA+G+M groups compared to control and HA alone (P < 0.00l). Bone morphogenetic protein-2 was expressed with varying degrees in all groups, without any difference among them. Within the limitations of the present study, HA matrix, used alone or in combination with G and M, did not contribute significantly to bone regeneration in rat calvarial bone defects.Publication Metadata only Multidisciplinary Therapy in a Patient with Amelogenesis Imperfecta: A Case Report With 5-Year Follow-Up(AVES PRESS LTD, 2017) ÖZTÜRK ÖZENER, HAFİZE; Ozener, Hafize Ozturk; Gemalmaz, Deniz; Kuru, BaharAmelogenesis imperfecta (AI) is a hereditary disorder that disrupts the formation of dental enamel in the primary and permanent dentition in the absence of systemic manifestations. The main concerns are caries susceptibility, poor esthetics, and generalized sensitivity. Treating these defects is not only important for esthetics and function but also for psychosocial health. Treatment planning for patients with AI is related to many factors: age and socioeconomic status of the patient, type and severity of the disorder, and the intraoral situation. In this case report, the 5-year results of a periodontal leveling process and fixed prosthetic restoration performed to regain esthetic and functional requirements in a female patient diagnosed with hypomature AI are presented.Publication Metadata only Probiotics in periodontal therapy(AVES PRESS LTD, 2015) ÖZTÜRK ÖZENER, HAFİZE; Ozener, Hafize Ozturk; Kuru, Bahar ErenProbiotics, defined as live microorganisms which are beneficial for health, are being used in the treatment of gastrointestinal disorders with success for many years. In recent years, researchers have sparked interest in the efficiency of the probiotics in periodontal health and treatment, based on their effects to support the immune system and suppress pathogenic microorganisms. The role and activity of probiotics in periodontal therapy are evaluated in this review. Probiotic research in periodontology is still in its start up phase. Nevertheless, pioneering results in periodontal health and periodontal therapy are encouraging, and with these data, a certain basis for the generation of further exhaustive and long-term studies are warranted.