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ALPAY, HARİKA

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Author: GÖKCE, İBRAHİM ×

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Now showing 1 - 10 of 66
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    PublicationOpen Access
    Is renal abscess still a problem?
    (MARMARA UNIV, FAC MEDICINE, 2021-01-26) ALPAY, HARİKA; Sak, Mehtap; Gokce, Ibrahim; Cicek, Neslihan; Guven, Sercin; Ergelen, Rabia; Yildiz, Nurdan; Alpay, Harika
    Renal abscess, the accumulation of infected fluid in the kidney, is a rare condition seen in children as well as adults. It leads to long term hospital admission and antibiotic use. Early diagnosis is an important factor in the outcome of renal abscess because the management may differ. Urinalysis test results and radiologic imaging findings of the patients who are admitted to hospital with complaints of fever, vomiting, abdominal pain or flank pain are important for the early diagnosis. Undertreated cases have high risk for renal scar formation. In this paper, we aim to present three pediatric patients, who showed the complication of renal abscess and were treated with long term antibiotic use without a need for surgical drainage.
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    Böbrek nakli sonrası covıd-19 enfeksiyonu ile presente olan akut nonketotik ağır hiperglisemi
    (2022-04-17) GÖKCE, İBRAHİM; ALPAY, HARİKA; Yıldız N., Demirci Bodur E., Kahveci A., Çiçek N., Güven S., Nisa Türkkan Ö., Pul S., Haliloğlu B., Gökce İ., Alpay H.
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    PublicationOpen Access
    ADPedKD: A Global Online Platform on the Management of Children With ADPKD
    (ELSEVIER SCIENCE INC, 2019-09) ALPAY, HARİKA; De Rechter, Stephanie; Bockenhauer, Detlef; Guay-Woodford, Lisa M.; Liu, Isaac; Mallett, Andrew J.; Soliman, Neveen A.; Sylvestre, Lucimary C.; Schaefer, Franz; Liebau, Max C.; Mekahli, Djalila; Adamczyk, P.; Akinci, N.; Alpay, H.; Ardelean, C.; Ayasreh, N.; Aydin, Z.; Bael, A.; Baudouin, V; Bayrakci, U. S.; Bensman, A.; Bialkevich, H.; Biebuyck, A.; Boyer, O.; Bjanid, O.; Brylka, A.; Caliskan, S.; Cambier, A.; Camelio, A.; Carbone, V; Charbit, M.; Chiodini, B.; Chirita, A.; Cicek, N.; Cerkauskiene, R.; Collard, L.; Conceicao, M.; Constantinescu, I; Couderc, A.; Crapella, B.; Cvetkovic, M.; Dima, B.; Diomeda, F.; Docx, M.; Dolan, N.; Dossier, C.; Drozdz, D.; Drube, J.; Dunand, O.; Dusan, P.; Eid, L. A.; Emma, F.; Espino Hernandez, M.; Fila, M.; Furlano, M.; Gafencu, M.; Ghuysen, Ms; Giani, M.; Giordano, M.; Girisgen, I; Godefroid, N.; Godron-Dubrasquet, A.; Gojkovic, I; Gonzalez, E.; Gokce, I; Groothoff, J. W.; Guarino, S.; Guffens, A.; Hansen, P.; Harambat, J.; Haumann, S.; He, G.; Heidet, L.; Helmy, R.; Hemery, F.; Hooman, N.; Ilanas, B.; Jankauskiene, A.; Janssens, P.; Karamaria, S.; Kazyra, I; Koenig, J.; Krid, S.; Krug, P.; Kwon, V; La Manna, A.; Leroy, V; Litwin, M.; Lombet, J.; Longo, G.; Lungu, A. C.; Mallawaarachchi, A.; Marin, A.; Marzuillo, P.; Massella, L.; Mastrangelo, A.; McCarthy, H.; Miklaszewska, M.; Moczulska, A.; Montini, G.; Morawiec-Knysak, A.; Morin, D.; Murer, L.; Negru, I; Nobili, F.; Obrycki, L.; Otoukesh, H.; Ozcan, S.; Pape, L.; Papizh, S.; Parvex, P.; Pawlak-Bratkowska, M.; Prikhodina, L.; Prytula, A.; Quinlan, C.; Raes, A.; Ranchin, B.; Ranguelov, N.; Repeckiene, R.; Ronit, C.; Salomon, R.; Santagelo, R.; Saygili, S. K.; Schaefer, S.; Schreuder, M.; Schurmans, T.; Seeman, T.; Segers, N.; Sinha, M.; Snauwaert, E.; Spasojevic, B.; Stabouli, S.; Stoica, C.; Stroescu, R.; Szczepanik, E.; Szczepanska, M.; Taranta-Janusz, K.; Teixeira, A.; Thumfart, J.; Tkaczyk, M.; Torra, R.; Torres, D.; Tram, N.; Utsch, B.; Vande Walle, J.; Vieux, R.; Vitkevic, R.; Wilhelm-Bals, A.; Wuehl, E.; Yildirim, Z. Y.; Yuksel, S.; Zachwieja, K.
    Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic cause of renal failure. For several decades, ADPKD was regarded as an adult-onset disease. In the past decade, it has become more widely appreciated that the disease course begins in childhood. However, evidence-based guidelines on how to manage and approach children diagnosed with or at risk of ADPKD are lacking. Also, scoring systems to stratify patients into risk categories have been established only for adults. Overall, there are insufficient data on the clinical course during childhood. We therefore initiated the global ADPedKD project to establish a large international pediatric ADPKD cohort for deep characterization. Methods: Global ADPedKD is an international multicenter observational study focusing on childhood-diagnosed ADPKD. This collaborative project is based on interoperable Web-based databases, comprising 7 regional and independent but uniformly organized chapters, namely Africa, Asia, Australia, Europe, North America, South America, and the United Kingdom. In the database, a detailed basic data questionnaire, including genetics, is used in combination with data entry from follow-up visits, to provide both retrospective and prospective longitudinal data on clinical, radiologic, and laboratory findings, as well as therapeutic interventions. Discussion: The global ADPedKD initiative aims to characterize in detail the most extensive international pediatric ADPKD cohort reported to date, providing evidence for the development of unified diagnostic, follow-up, and treatment recommendations regarding modifiable disease factors. Moreover, this registry will serve as a platform for the development of clinical and/or biochemical markers predicting the risk of early and progressive disease.
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    Tübülointertisyel nefrit sonrası geç ortaya çıkan üveit, farklı bir TİNU olgusu
    (2022-02-20) GÖKCE, İBRAHİM; ALPAY, HARİKA; Bayraktar S., Bodur E., Pul S., Türkkan Ö., Güven S., Çiçek N., Yıldız N., Gökce İ., Alpay H.
    Tübülointertisyel nefrit ve üveit(TİNU) sendromu,akut tübülointertisyel nefritin(TİN) nadir bir alt grubudur.Genellikle benign seyirli TİN ve relapslar ile seyreden üveit kliniğiyle karakterizedir.Üveit, TİN başlangıcından 2 ay önce gelişebileceği gibi,TİN sonrası 14.aya kadar gelişebilir.Bu olgu sunumunda,TİN tanısından 10 ay sonra üveit saptanan hasta sunulacaktır.
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    Tübülointertisyel nefrit sonrası geç ortaya çıkan üveit: farklı bir tinu olgusu
    (2022-05-26) GÖKCE, İBRAHİM; ALPAY, HARİKA; Bayraktar S., Demirci Bodur E., Güven S., Eker N., Polat Pul S., Nisa Türkkan Ö., Çiçek N., Yıldız N., Gökce İ., Gülnur Tokuç A., et al.
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    Hiperimmunoglogulin D sendromlu bir hastada homozigot P.V377I mutasyonuna bağlı amiloidoz
    (2022-03-26) GÖKCE, İBRAHİM; ALPAY, HARİKA; Demirci Bodur E., Gökce İ., Sözeri B., Alavanda C., Farmanlı O., Ata P., Kaya H., Alpay H.
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    Renal artery stenosis and aneurysm in a child presenting with hypokalemia, metabolic alkalosis and hypertension [Hipokalemi, metabolik alkaloz ve hipertansiyon ile bavuran bir çocukta renal arter darliǧi ve anevrizmas]
    (Turkish Society of Nephrology, 2016) ALPAY, HARİKA; Gökce I., Bölükbaş B.F., Buǧur I., Güven S., Deniz N.Ç., Altuntaş Ü., Yildiz N., Ergelen R., Baltacioǧlu F., Alpay H.
    Renovascular hypertension is one of the important causes of secondary hypertension in children and can be caused by many different diseases, with the most common being fibromuscular dysplasia (FMD) and Takayasu arteritis (TA). The differential diagnosis between TA and FMD seems to be difficult and much less certain than is generally assumed in many cases. Here we present a case report of an 11-yearold girl with FMD presenting with hypokalemia, metabolic alkalosis and hypertension secondary to renal artery stenosis and hyperreninemic hyperaldosteronism.
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    Botulinum toksin enjeksiyonunun nadir bir komplikasyonu: peritonit ve pyelonefrit
    (2022-02-20) GÖKCE, İBRAHİM; ALPAY, HARİKA; Bodur E., Şeker Z., Türkkan Ö., Pul S., Abidoğlu A., Güven S., Çiçek N., Yıldız N., Gökce İ., Akgül A., et al.
    Botulinum toksin A enjeksiyonu(BTE) nörojenik mesanesi(NM) olan hastalarda detrusor aşırı aktivitesini azaltmak,mesane kapasitesini iyileştirmek amacıyla yapılan bir tedavidir.En sık görülen lokal yan etkileri makroskopik hematüri,idrar retansiyonu,işemede güçlük ve üriner sistem enfeksiyonudur(ÜSE).Bu olgu sunumunda,BTE sonrası peritonit,pyelonefrit ve ürosepsis gelişen iki pediatrik olgu tartışılmıştır.
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    Henoch schönlein purpura kliniği ile başvuran C3 glomerülopati olgusu
    (2022-02-20) GÖKCE, İBRAHİM; ALPAY, HARİKA; Dikencik G., Bodur E., Pul S., Türkkan Ö., Güven S., Çiçek N., Yıldız N., Gökce İ., Alpay H.
    Çocukluk çağının en sık görülen vasküliti olan Henoch Schönlein Purpurası (HSP), küçük damarlarda vaskülite neden olup,damar duvarlarında IgA içerikli immünkompleks birikimi ile karakterizedir. Hastalarda sıklıkla pal pabl purpura, karın ağrısı,artrit/artralji ve böbrek tutulumu görülür.C3 Glomerulopatisi (C3G), kompleman yolaklarının uygunsuz sistemik aktivasyonu sonucu gelişen nadir bir glomerulopati grubudur.Glomerüllerde kompleman birikimi görülür. Bu olgu sunumunda, klinik bulguları ile HSP düşündüren ve takibinde C3G tanısı alan hasta sunulacaktır.
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    PublicationOpen Access
    A case of granulomatosis of polyangiitis presenting with COVID-19 infection: False-positivity or co-existence?
    (2023-09-29) KAYA, MİTHAT; GÖKCE, İBRAHİM; ALPAY, HARİKA; KAYA M., GÖKCE İ., Guven S., Pul S., ALPAY H.
    Coronavirus disease 2019 (COVID-19) was declared a global pandemic and a public health emergency worldwide in March 2020. COVID-19 presents with non-specific symptoms of the upper airway and pulmonary system, which can overlap with other diseases involving the respiratory system as granulomatosis with polyangiitis (GPA). Both diseases have high morbidity and mortality rates and it is important to promptly differentiate and treat them. Real-time reverse transcriptase polymerase chain reaction (RT-PCR) is currently the recommended method for diagnosing COVID-19. Antibody-based tests are used to diagnose both pat and current COVID-19 infections. We present a previously healthy thirteen-year-old girl who was admitted with upper airway symptoms and pulmonary involvement, and progressed to acute kidney failure. Laboratory findings showed leukocytosis, anemia, elevated kidney function tests and 2+ proteinuria. Computed tomography (CT) of the lungs showed multiple nodules, cavities, and ground-glass opacities (GGOs). We performed RT-PCR tests for COVID-19 for three times. Results were all negative, but the COVID-19 immunoglobulin (Ig)M test sent simultaneously was positive. Based on the cytoplasmic antineutrophilic cytoplasmic antibody (c-ANCA) positivity, upper airway, pulmonary, and renal involvement, she was diagnosed as GPA. This report highlights that COVID-19 antibody tests can be false-positive in patients with autoimmune diseases including GPA.