Person: CESUR, SÜMEYYE
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CESUR
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SÜMEYYE
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Publication Metadata only Fabrication and characterization of pla/sa/ha composite nanofiber by electrospinning for bone tissue engineering applications(2018-07-18) CESUR, SÜMEYYE; EKREN, NAZMİ; KILIÇ, OSMAN; OKTAR, FAİK NÜZHET; BİLĞİÇ ALKAYA, DİLEK; AYAZ SEYHAN, SERAP; GÜNDÜZ, OĞUZHAN; Cesur S., Ekren N., Kılıç O., Oktar F. N., Bilğiç Alkaya D., Ayaz Seyhan S., Ege Z. R., Gündüz O.Publication Metadata only Preparation and characterization of silver-doped hydroxyapatite from seashell by different methods(2018-09-08) AYAZ SEYHAN, SERAP; BİLĞİÇ ALKAYA, DİLEK; CESUR, SÜMEYYE; OKTAR, FAİK NÜZHET; GÜNDÜZ, OĞUZHAN; , Ayaz Seyhan S., Bilğiç Alkaya D., Öztürk B. N., Cesur S., Topsakal A., Oktar F. N., Gündüz O.Publication Metadata only Hydroxyapatıte is bıomaterıals: its chemıcal synthesıs characterızatıon shell of cypaea annulus(2018-09-08) BİLĞİÇ ALKAYA, DİLEK; AYAZ SEYHAN, SERAP; CESUR, SÜMEYYE; OKTAR, FAİK NÜZHET; GÜNDÜZ, OĞUZHAN; Bilğiç Alkaya D., Ayaz Seyhan S., Öztürk B. N., Cesur S., Topsakal A., Oktar F. N., Gündüz O.Publication Metadata only Preparatıon of hydroxyapatıte biomaterıals for benzoic acid delıvery from scotch bonnets seashell by microwave processing(2018-09-08) BİLĞİÇ ALKAYA, DİLEK; AYAZ SEYHAN, SERAP; CESUR, SÜMEYYE; OKTAR, FAİK NÜZHET; GÜNDÜZ, OĞUZHAN; Öztürk B. N., Bilğiç Alkaya D., Ayaz Seyhan S., Cesur S., Topsakal A., Oktar F. N., Gündüz O.Publication Metadata only Electrospun multilayer nanofiber based intelligent drug delivery and release system(2018-07-18) OKTAR, FAİK NÜZHET; YILMAZ, BETÜL; CESUR, SÜMEYYE; GÜNDÜZ, OĞUZHAN; Ege Z. R., Oktar F. N., Akan A., Kuruca D. S., Yılmaz B., Erdemir G., Cesur S., Gündüz O.Publication Metadata only Multilayer patches for the treatment of corneal perforations caused by infections(2022-09-28) CESUR, SÜMEYYE; TINAZ, GÜLGÜN; ŞENGÖR, MUSTAFA; OKTAR, FAİK NÜZHET; GÜNDÜZ, OĞUZHAN; Kijeńska-Gawrońska ., İlhan E., Cesur S., Sulutaş R. B., Pilavcı E., Dalbayrak B., Kaya E., Arısan E. D., Tınaz G., Şengör M., et al.Publication Metadata only Fabrication and characterization of hazelnut shellpowder with reinforced polymer compositenanofibers(2018-09-14) KARTAL, İLYAS; OKTAR, FAİK NÜZHET; EKREN, NAZMİ; İNAN, AHMET TALAT; GÜNDÜZ, OĞUZHAN; CESUR, SÜMEYYE; Şengör İ., Cesur S., Kartal İ., Oktar F. N., Ekren N., İnan A. T., Gündüz O.Publication Metadata only Fluconazole and cinnamaldehyde loaded-multilayer elektrospun nanofibers for the treatment of fungal keratitis(2022-06-24) CESUR, SÜMEYYE; OKTAR, FAİK NÜZHET; GÜNDÜZ, OĞUZHAN; İlhan E., Cesur S., Oktar F. N., Gündüz O.Inflammation of the cornea due to physical, chemical and infectious causes is known as keratitis[1]. Fungi are one of the most challenging species to diagnose and treat among the organisms that cause keratitis. Moreover, fungal keratitis has been proven to be more virulent and destructive than keratitis caused by bacterias[2]. In this study, two-layer polyvinyl alcohol and gelatin (PVA/GEL) nanofibers loaded with different biological agents, which accelerate wound closure by suppressing the disadvantages of traditional methods in the treatment of fungal keratitis, were produced by the electrospinning method. Cinnamaldehyde (CA), an FDA-approved volatile molecule found in cinnamon essential oil, and fluconazole (FLU), an antifungal drug, were incorporated into PVA/GEL nanofibers to inhibit the growth and biofilm formation of Candida albicans, one of the pathogens that cause fungal keratitis. The morphology, and chemical structures of the produced pure (PVA/GEL), FLU loaded (PVA/GEL/FLU), CA loaded (PVA/GEL/CA), and combined FLU and CA loaded (PVA/GEL/COM) nanofibers were analysed by scanning electron microscopy (SEM), and Fourier-transform infrared spectroscopy (FT-IR), respectively. The mechanical analysis and drug release kinetics of the nanofibers were investigated. PVA/GEL/FLU, PVA/GEL/CA and PVA/GEL/FLU/COM nanofibers were evaluated for their antifungal and antibiofilm activity against Candida albicans. Results showed that PVA/GEL/FLU and PVA/GEL/COM nanofibers have significant antifungal activity and inhibited biofilm formation by 37% and 49%, respectively. The originality of this study lays in the design of the multilayer electrospun nanofibers, which are loaded with both biofilm inhibitor agent and an antifungal drug. This kind of construct can be utilised in the treatment of fungal keratitis and to produce patches that accelerate wound healing and allow controlled release of the bio-active agents.Publication Metadata only Investıgatıon of chıtosan / trıcalcıum phosphate (Tcp) composıte powders from scotch bonnets ( Semıcassıs Granulata) as a drug controlled release matrıces(2018-07-18) BİLĞİÇ ALKAYA, DİLEK; AYAZ SEYHAN, SERAP; CESUR, SÜMEYYE; GÜNDÜZ, OĞUZHAN; OKTAR, FAİK NÜZHET; Bilğiç Alkaya D., Ayaz Seyhan S., Cesur S., Gündüz O., Oktar F. N.Publication Metadata only Productıon of hydroxyapatite/poly(vinyl alcohol) based scaffold for drug delıvery from orange spıny oyster seashell (spondylus barbatus)(2018-07-18) AYAZ SEYHAN, SERAP; BİLĞİÇ ALKAYA, DİLEK; CESUR, SÜMEYYE; OKTAR, FAİK NÜZHET; GÜNDÜZ, OĞUZHAN; Ayaz Seyhan S., Bilğiç Alkaya D., Cesur S., Oktar F. N., Gündüz O.