Person: DOĞAN, AHMET
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DOĞAN
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AHMET
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Publication Metadata only Turkish folk medicinal plants, IX: Ovacik (Tunceli) [Türkiye'nin halk ilacı bitkileri, IX: Ovacık (Tunceli)](Marmara University, 2010) DOĞAN, AHMET; Tuzlaci E., Doǧan A.The aim of this study was made to reveal the plants used as traditional folk medicine in Ovaci{dotless}k (Tunceli). For this purpose, the field works have been done between May 2007-May 2008 in April, May, June and July lasting for 30 days, in total. During this research all the settlement centers (including 33 villages) have been visited, the specimens of the plants used as folk remedies have been collected and the information such as local names, ailments treated or therapeutic effects, plant parts used, method of administration, dosage, duration of treatment have been recorded. The collected plant specimens are kept in the Herbarium of the Faculty of Pharmacy, Marmara University (MARE). As a result of identification of 76 plant specimens, 67 species used as a traditional folk medicine, have been determined. Among them 65 species are wild and 2 species are cultivated plants. These plants and their local usage in treatment are presented in a table in the text. It was found out that the plants recorded in Ovaci{dotless}k are mostly used for cold, diabetes and wound.Publication Open Access An Ethnobotanical study of medicinal plants in Taşköprü (Kastamonu–Turkey)(2022-10-20) ŞENKARDEŞ, İSMAİL; DOĞAN, AHMET; EMRE, GİZEM; ŞENKARDEŞ İ., DOĞAN A., EMRE G.Copyright © 2022 Senkardes, Dogan and Emre.This pharmaceutical ethnobotanical research was carried out in Taşköprü District in Kastamonu, in northern Anatolia. It assembles the elaborations of plants used as folk medicines, and the ethnopharmacological data collected in the course of in-person semi-structured interviews with an open-ended questionnaire. The study’s aims were two-fold: gathering and identifying plants that the local inhabitants use therapeutically, and recording information related to traditional folk medicine (primarily for humans, and if extant for animals). The plants were gathered during several outings between May 2016 and July 2018. The organization of the data was based on the use-reports (UR) and was done according to the ICPC-2 classification. In addition, cultural importance index (CI) and informant consensus factor (FIC) calculations were made for the data collected. The research identified 101 plant taxa of 31 families used in folk medicine. Of these, 89 were wild and 12 were cultivated taxa. In total, 499 medicinal uses were determined. The CI values indicated that the most significant medicinal plant specimens were Pinus nigra subsp. pallasiana (0.78), P. sylvestris var. hamata (0.75) and Plantago lanceolata, P. major subsp. intermedia and P. major subsp. major (0.58 each). The most prevalent families were Asteraceae (2.14), Rosaceae (1.93), Pinaceae (1.81) and Plantaginaceae (1.74). Respiratory system (0.95), skin and subcutaneous tissue (0.94), nervous system (0.92) and circulatory system disorders (0.88) and ethnoveterinary uses (0.89) had the highest FIC values. The most frequently used preparation process was observed to be decoction (38.4%) and the most commonly utilized plant parts were aerial (21%). Along with recording 20 plant taxa as medicinal plants for the first time, this study documented a total of 303 new therapeutic uses. This study concludes with the finding that traditional knowledge of medicinal plants remains prevalent in Ta rticularly among its rural inhabitants.Publication Open Access An Ethnobotanical Study of Medicinal Plants in Mersin (Turkey)(FRONTIERS MEDIA SA, 2021-07-07) DOĞAN, AHMET; Emre, Gizem; Dogan, Ahmet; Haznedaroglu, Mehmet Zeki; Senkardes, Ismail; Ulger, Mahmut; Satiroglu, Aysen; Emmez, Berivan Can; Tugay, OsmanThis comprehensive ethnobotanical study carried out in Mersin province, which is located in the southern part of Anatolia, east of the Mediterranean Sea, compiles details on plants used in folk medicine and ethnopharmacological information obtained through face-to-face interviews. The aim was to collect and identify plants used for therapeutic purposes by local people and to record information on traditional herbal medicine. Plant specimens were collected in numerous excursions. Additionally, informant consensus factor and use value (UV) were calculated for information gathered. This study identifies 93 plant taxa belonging to 43 families and records their usage in folk medicine; 83 taxa are wild and the remaining 10 are cultivated. The most commonly used plants belong to Lamiaceae, representing 15.0% of the total, while the Rosaceae, Malvaceae, Hypericaceae, Asteraceae and Cupressaceae families each represented another 5.4%. As a result of this investigation, we determine 189 medicinal usages of 93 taxa. The UV values indicate that the most important medicine plants are Hypericum perforatum (0.80), Cedrus libani (0.78), Quercus coccifera (0.77), Arum dioscoridis (0.76) and Juniperus drupaceae (0.74). We observed that most of the drugs are prepared using the infusion method (27.6%). As a conclusion, the study finds that traditional folk medicine usage is still common, especially among the rural population of Mersin.Publication Open Access Bioactivities of Achillea phrygia and Bupleurum croceum based on the composition of phenolic compounds: In vitro and in silico approaches(2017-09-01) EMRE, GİZEM; DOĞAN, AHMET; Zengin G., EMRE G., Mollica A., Haznedaroglu M. Z. , DOĞAN A., Aktumsek A.This study presents the effects of the Achillea phrygia Boiss. et Bal. and Bupleurum croceum Fenzl. extracts obtained by different solvents (ethyl acetate, methanol and water) on selected enzyme inhibitory effects and antioxidant ability with screening bioactive compounds. Total and individual bioactive compounds were detected by spectrophotometric and HPLC-DAD techniques. Antioxidant abilities were evaluated by different methods including free radical scavenging (ABTS and DPPH), reducing power (CUPRAC and FRAP), phosphomolybdenum and metal chelating. Enzyme inhibitory effects were tested against cholinesterases, tyrosinase, amylase, glucosidase and lipase. Total phenolic contents were ranged from 20.52 mgGAE/g extract (B. croceum methanol extract) to 41.13 mgGAE/g extract (A. phrygia methanol extract). Generally, methanol and water extracts showed the strongest antioxidant abilities, while the ethyl acetate extracts had the most promising enzyme inhibitory effects. HPLC analysis revealed the abundance of some phenolics including rutin, quercetin, sinapic acid and chlorogenic acid, respectively. These components were also assessed using molecular modelling with the aim to study their docking properties on a set of six enzymes used in this study. Overall, these species could be suggested as valuable sources of natural-bioactive agents for developing new functional, pharmacological and health promoting ingredients. (C) 2017 Elsevier Ltd. All rights reserved.Publication Metadata only An ethnobotanical study of medicinal plants in Acipayam (Denizli-Turkey)(ELSEVIER GMBH, URBAN & FISCHER VERLAG, 2017) DOĞAN, AHMET; Bulut, Gizem; Haznedaroglu, Mehmet Zeki; Dogan, Ahmet; Koyu, Halil; Tuzlaci, ErtanA comprehensive ethnobotanical study was conducted in Acipayam, situated in the western part of Turkey. This paper includes details of plants used in folk medicine and ethnopharmacological information obtained during this study. The aim of the authors was to collect and identify plants used by local people for therapeutic purposes and to present information about traditional herbal medicine. Plant specimens collected during field-work form the subject of this investigation. Information was obtained by means of open and semi-structured interviews with local people. In addition, cultural importance index (CI) and use report (UR) values were calculated. Ninety-one taxa of plants used in folk medicine and belonging to 38 families were identified in this study. Of these, 82 species were wild, and 9 species were cultivated. The most common families were Lamiaceae (18.7%), Asteraceae (14.3%) and Rosaceae (6.6%). Consequently, 191 medicinal uses (remedies) of 91 taxa were recorded. According to the use reports (UR), the most important medicinal plants were Cydonia oblonga (99 UR), Juniperus oxycedrus subsp. oxycedrus (99 UR), Pinus brutia (98 UR), Hypericum perforatum (90 UR), Viscum album subsp. austriacum (82 UR) and Salvia tomentosa (80 UR). Infusion (38.2%) was the most common preparation method used within the research area. The ethnomedicinal capabilities of eight species (Amelanchier parviflora var. dentata, Echinops viscosus subsp. bithynicus, Onopordum sibthorpianum, Origanum hypericifolium, Quercus trojana, Salvia adenophylla, Sideritis montana. subsp. remota and Tamarix smyrnensis) have been recorded for the first time in Turkey.