Person:
YARAT, AYŞEN

Profile Picture

Email Address

Birth Date

Research Projects

Organizational Units

OrgUnit Logo
Organizational Unit

Job Title

Last Name

YARAT

First Name

AYŞEN

Name

Filters

2016 - 20192
Reset filters

Settings

Author: AKYÜZ, SERAP HATİCE × Subject: ANTIOXIDANT ×

Search Results

Now showing 1 - 2 of 2
  • Thumbnail Image
    PublicationOpen Access
    Tooth replantation with adipose tissue stem cells and fibrin sealant: microscopic analysis of rat's teeth
    (SPRINGER INTERNATIONAL PUBLISHING AG, 2016-12) YARAT, AYŞEN; Demirel, Sezin; Yalvac, Mehmet Emir; Tapsin, Sidika; Akyuz, Serap; Ak, Esin; Cetinel, Sule; Yarat, Aysen; Sahin, Fikrettin
    Treatment for dental avulsion cases is early or late replantation of the traumatized teeth. Prognosis of the replanted tooth depends on the level of periodontal injury. Adipose tissue stem cells (ATSCs) were reported to improve periodontal ligament tissue (PDL) regeneration. Fibrin sealant (FS) contains thrombin and fibrinogen to form an adhesive fibrin clot routinely used in surgical procedures. Here, we aimed to investigate the effects of ATSCs + FS treatment on healing of PDL after tooth replantation in a rat model. After 60 min of extraction, maxillary central incisor teeth were replanted with ATSCs + FS. Two months later, the rats were sacrificed and hemimaxilla blocks were dissected out for histological analysis. The results showed that there was a significant improvement in histological findings of ATSCs + FS treated group compared to only FS treated and non-treated groups corresponding to reduced inflammatory resorption and increased new PDL formation. Furthermore, the ankylosis levels were lowered after ATSCs + FS treatment. Singular use of FS improved PDL healing moderately. Our results indicated that ATSCs + FS treatment improves PDL healing after tooth replantation suggesting a new therapeutic potential in the treatment of dental avulsion cases.
  • No Thumbnail Available
    PublicationMetadata only
    Antibacterial and photodynamic effects of some plant extracts for cavity disinfection
    (ELSEVIER, 2019) YARAT, AYŞEN; Akyuz, Serap; Chousein (Ntemir), Ozlem Moufti; Sacan, Ozlem; Yanardag, Refiye; Kalayci, Sadik; Yarat, Aysen; Sahin, Fikrettin
    Background: In current dental treatments, with the aim of a preventive approach,it is argued that removing only the infected layer of dentin is sufficient for cavity preparation. However it is impossible to be sure that the infected layer was completely removed. In addition, the cause of secondary caries and post operative sensitivities has been reported as residual bacteria in some studies. The aim of this study is to investigate the antibacterial and photo-active properties of Cotinus coggygria Scop., Rumex cristatus DC., Beta vulgaris L.var.cicla and Eruca sativa aqueous extracts, and to investigate their usefulness for cavity disinfection in dentistry. Method: The aqueous solutions of plant extracts were prepared to be at a maximum concentration and the Streptococcus mutans solutions mixed with phosphate buffered saline to give 10(8) cfu/mL. A 430-480 nm wavelength light source was used for the irradiation. Three different applications were made: extract + Streptococcus mutans mixture exposed to ligh; extract + Streptococcus mutans mixture that was not exposed to light and S. mutans exposed to light. Results: No antibacterial effect was found for the second and third applications. In the first application, however, irradiation with extract + Streptococcus mutans mixture reduced the number of microorganisms in the beginning by 99% for only Rumex cristatus DC. extract (log 2). Conclusion. Rumex cristatus DC. extract can be used as art alternative in photo-active disinfection of cavities in dentistry.