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LÜLECİ, NİMET EMEL

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LÜLECİ

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NİMET EMEL

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2007 - 200912010 - 20192
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Author: KESKİN, YAŞAR ×

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    Cadmium, lead, mercury and copper in fish from the Marmara Sea, Turkey
    (SPRINGER, 2007) LÜLECİ, NİMET EMEL; Keskin, Yasar; Baskaya, Ruhtan; Oezyaral, Oguz; Yurdun, Tuerkan; Lueleci, Nimet Emel; Hayran, Osman
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    PublicationOpen Access
    The Prevalence of Osteoporosis in the Thrace Region of Turkey: A Community-Based Study
    (AVES, 2014-11-26) AKYÜZ, GÜLSEREN DERYA; Keskin, Yasar; Cekin, Murat Dincer; Gunduz, Hakan; Luleci, Nimet Emel; Giray, Esra; Sur, Haydar; Akyuz, Gulseren
    Objective: This study was planned as a community-based research study to estimate the prevalence of osteoporosis and explore related risk factors in the Thrace region of Turkey. Material and Methods: The community-based study involved a total of 620 people, 498 women and 122 men, aged between 40 and 89 years. A questionnaire on the medical history and lifestyles of the participants was applied with a face-to-face interview. Body weight height, and arm span of each participant were measured, together with bone mineral density at the middle phalanges of the second, third, and fourth digits of the non-dominant hand using dual-energy X-ray laser absorptiometry. Results: Age, clothing, lack of regular exercise, and giving birth to more than two children seem to contribute to osteoporosis, while high education, high economic level, tea and moderate alcohol consumption, oral contraceptive use, and hormone replacement therapy seem to retard osteoporosis. Osteoporotic patients had more fractures in the past. Height and weight were significantly lower in osteoporotic women. Conclusion: Lifestyle affects the prevalence of osteoporosis. Drinking tea and alcohol seems to be controversial with regard to osteoporosis risk.
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    PublicationOpen Access
    ASSOCIATION OF GENETIC POLYMORPHISMS IN THE Matrix Gla Protein (MGP) GENE WITH CORONARY ARTERY DISEASE AND SERUM MGP LEVELS
    (MACEDONIAN ACAD SCIENCES ARTS, 2019-12-21) LÜLECİ, NİMET EMEL; Karsli-Ceppioglu, S.; Yazar, S.; Keskin, Y.; Karaca, M.; Luleci, N. E.; Yurdun, T.
    Matrix Gla protein (MGP) is an important regulatory protein for inhibition of calcification in the vessel wall and cartilage. The MGP gene polymorphisms are suspected to increase the risk of extracellular calcification through altering the related gene expression and serum MGP levels. The goal of this study was to examine the correlation between rs4236 (Thr83-Ala), rs12304 (Glu60-X) and rs1800802 (T138-C) polymorphisms of the MGP gene and coronary artery calcification. Serum MGP levels of 168 subjects who had undergone coronary angiography were analyzed along with genotyping of MGP gene polymorphisms. The results indicated that serum MGP levels were significantly associated with rs4236 and rs1800802 polymorphisms of the MGP gene with the occurrence of coronary artery diseases (CAD). Allelic distributions of MGP gene polymorphisms and serum MGP levels, respectively, were not significantly interconnected with the presence of CAD. Our results revealed that serum MGP levels of CAD patients show association with rs4236 and rs1800802 polymorphisms, but serum MGP levels alone do not directly reflect the risk of CAD. The role of MGP genetic variants on formation and progression of arterial calcification should be regarded in cardiovascular diseases.