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KARADAĞ SAYGI, NAİME EVRİM

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KARADAĞ SAYGI

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NAİME EVRİM

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20201
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Subject: Botulinum toxin ×

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    Effects of dynamic lycra orthosis as an adjunct to rehabilitation after botulinum toxin-A injection of the upper-limb in adults following stroke: A single-blinded randomized controlled pilot study
    (TAYLOR & FRANCIS LTD, 2020) KARADAĞ SAYGI, NAİME EVRİM; Giray, Esra; Atalay, Kardelen Gencer; Eren, Nurullah; Gunduz, Osman Hakan; Karadag-Saygi, Evrim
    Background: Dynamic lycra splints are proposed to modify hypertonicity due to their characteristics - neutral warmth, circumferential pressure, and creating a low-intensity prolonged stretch on hypertonic muscles - to contribute to increased sensory awareness of the involved limb. Objectives: The aim of this study was to investigate the effects of dynamic lycra orthosis as an adjunct to botulinum toxin-A injection and rehabilitation of the upper-limb in adults following stroke. Methods: Patients who had suffered a stroke more than three months previously were randomized into two groups: lycra sleeve plus rehabilitation (n = 10) and only-rehabilitation group (n = 10). After botulinum toxin injection, both groups underwent an upper-limb rehabilitation program. The intervention group wore a lycra sleeve for eight hours a day, five days a week for three weeks in addition to the rehabilitation program. Fugl Meyer upper-limb motor score, Motricity index, Modified Ashworth scale, Box and Block test, Stroke Impact Scale and change in touch-detection thresholds of the fingers measured via Semmes-Weinstein monofilaments were assessed by blinded investigators at before treatment, post-treatment (at 3 weeks) and three months post-treatment. This trial is registered with Clinicaltrials.gov, number NCT03546959. Results: There were no differences between groups in terms of Fugl Meyer upper-limb motor score, Motricity Index, Modified Ashworth scale, Box and Block test, Stroke Impact Scale and change in light touch threshold at any follow-up time points. Conclusions: Using lycra splints as an adjunct to an upper-limb rehabilitation program after stroke did not provide additional benefit in spasticity, upper-limb motor function, light touch threshold of fingers or stroke-specific quality-of-life.
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    PublicationOpen Access
    Consensus recommendations for botulinum toxin injections in the spasticity management of children with cerebral palsy during COVID-19 outbreak
    (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY) KARADAĞ SAYGI, NAİME EVRİM; Yalcinkaya, Ebru Yilmaz; Karadag Saygi, Evrim; Ozyemisci Taskiran, Ozden; Capan, Nalan; Kutlay, Sehim; Sonel Tur, Birkan; Ozlem, E. L.; Unlu Akyuz, Ece; Tekin, Suda; Ofluoglu, Demet; Zinnuroglu, Murat; Akpinar, Pinar; Ozekli Misirlioglu, Tugce; Huner, Berrin; Nur, Hakan; Caglar, Sibel; Sezgin, Melek; Tikiz, Canan; Ones, Kadriye; Icagasioglu, Afitap; Aydin, Resa
    Spasticity is the most common motor disturbance in cerebral palsy (CP). Lockdown in the COVID-19 outbreak has profoundly changed daily routines, and similarly caused the suspension of spasticity treatment plans. Besides, the delay in botulinum toxin (BoNT) injection, which is important in the management of focal spasticity, led to some problems in children. This consensus report includes BoNT injection recommendations in the management of spasticity during the COVID-19 pandemic in children with CP. In order to develop the consensus report, physical medicine and rehabilitation (PMR) specialists experienced in the field of pediatric rehabilitation and BoNT injections were invited by Pediatric Rehabilitation Association. Items were prepared and adapted to the Delphi technique by PMR specialists. Then they were asked to the physicians experienced in BoNT injections (PMR specialist, pediatric orthopedists, and pediatric neurologists) or COVID-19 (pediatric infectious disease, adult infectious disease). In conclusion, the experts agree that conservative management approaches for spasticity may be the initial steps before BoNT injections. BoNT injections can be administered to children with CP with appropriate indications and with necessary precautions during the pandemic.