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ULAĞ, SONGÜL

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SONGÜL

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Author: CESUR, SÜMEYYE × Subject: Engineering, Computing & Technology (ENG) ×

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Now showing 1 - 3 of 3
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    Fabrication, characterization and investigation of antibacterial activity of propolis substituted sodium alginate tissue scaffolds using three-dimensional (3d) printing technology
    (2021-06-05) UZUN, MUHAMMET; SU TORUN, SENA; ULAĞ, SONGÜL; AKSU, MEHMET BURAK; GÜNDÜZ, OĞUZHAN; CESUR, SÜMEYYE; Aarancı K., Uzun M., Su Torun S., Cesur S., Ulağ S., Amin A., Güncü M. M., Aksu M. B., Kolaylı S., Silva J., et al.
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    PublicationOpen Access
    Microfluidic systems for neural tissue engineering
    (Elsevier Science, Oxford/Amsterdam , 2023-01-01) CESUR, SÜMEYYE; ULAĞ, SONGÜL; GÜNDÜZ, OĞUZHAN; Cesur S., Ulağ S., Gündüz O.
    Damage to the nervous system due to illness or injury can cause serious and lasting loss of function or even fatal consequences. It is necessary to develop new treatment strategies to restore the function of the damaged nervous system.The optimal environment for nerve cell proliferation and differentiation is provided by neural tissue engineering. It aims to improve a new approximation for the therapy of nervous system diseases. Compared to 2D cell culture techniques, 3D cell culture systems ensure a more biomimetic environment and encourage more differentiation of cells. However, certain cell culture parameters have limitations in spatio-temporal control. With the advent of microfluidic systems, it can control the spatio-temporal dispersion of physical and chemical signals at the cellular level. In this section, microfluidic systems are explored as a tool to target both physical and chemical injury and recreate the post-injury environment, to study nerve injury at the cellular grade.
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    PublicationOpen Access
    Characterization of scaffolds for neural tissue engineering
    (Elsevier Science, Oxford/Amsterdam , 2023-01-01) CESUR, SÜMEYYE; ULAĞ, SONGÜL; Ulağ S., Cesur S., Ayran M. M., Bozlar M.
    With the advancement of tissue engineering techniques, the repair of nerve injuries has acquired a novel dimension. It is now appropriate to establish a scaffold that entirely mimics the biological and mechanical properties of real human tissue using tissue engineering techniques. In order to determine how well synthetic and/or natural polymers can construct optimal scaffolds, cells and growth factors can also be investigated to enhance the functionality of scaffolds. Studies are underway to design biodegradable, biocompatible, electrically conductive, and immunologically inert scaffolds. The primary objective is to accurately simulate the extracellular matrix in the human body and to expose the conjunction of biochemical, topographic, and electrical features employing different polymers, cells, and growth hormones. This chapter focuses on the importance of processing/engineering and characterization techniques for neural tissue scaffolds used to regenerate neural diseases.