Person: BİNNETOĞLU, ADEM
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BİNNETOĞLU
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ADEM
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Publication Metadata only Bacterial cellulose tubes as a nerve conduit for repairing complete facial nerve transection in a rat model(SPRINGER, 2020) BİNNETOĞLU, ADEM; Binnetoglu, Adem; Demir, Berat; Akakin, Dilek; Demirci, Elif Kervancioglu; Batman, CaglarPurpose Functionality of the facial nerve is cosmetically important. While many techniques have been investigated, early and effective treatment for traumatic facial nerve paralysis remains challenging. Here, we aim to examine bacterial cellulose (BC) as a new tubularization material for improving facial nerve regeneration. Methods Our study was performed on 40 female Sprague Dawley rats. Rats were randomly divided into four groups, with 10 rats per group. In all rats, the main trunk of the facial nerve was completely cut 8 mm before the branching point. For repairing the facial nerve, in group 1, the nerve was left to recover spontaneously (control group); in group 2, it was repaired by primary suturing (8.0 Ethilon sutures, Ethicon); in group 3, BC tubes alone were used to aid nerve repair; and in group 4, both BC tubes and primary sutures (8.0 Ethilon sutures) were used. After 10 weeks, the facial nerve regeneration was evaluated by the whisker movement test and electrophysiologically (nerve stimulation threshold and compound muscle action potential). Nerve regeneration was assessed by calculating the number of myelinated nerve fibers, and by microscopically evaluating the amount of regeneration and fibrosis. Results No significant difference was observed among the groups in terms of whisker movement and electrophysiological parameters (P > 0.05). We found that the numbers of regenerating myelinated fibers were significantly increased (P < 0.05) when BC tubes were used as a nerve conduit. Conclusions BC can be easily shaped into a hollow tube that guides nerve axons, resulting in better nerve regeneration after transection.Publication Metadata only Surgical complications of cochlear implantation: a 25-year retrospective analysis of cases in a tertiary academic center(SPRINGER, 2020) BİNNETOĞLU, ADEM; Binnetoglu, Adem; Demir, Berat; Batman, CaglarPurpose Despite the advances made in cochlear implantation techniques, the associated complication rates are still high. Here, we aimed to analyze cases, with extensive follow-up data, associated with a large sample of patients to identify complications related to cochlear implants and to present our surgical experience and the technique that we used in order to follow surgical rules/medical purpose to avoid any complications. Methods We retrospectively examined cases involving 2597 patients (1342 males; 1255 females; age 1-88 years) who underwent cochlear implantation procedures between November 1995 and July 2019, and we classified complications as minor and major. Results The mean age at the time of implantation was 6.48 (Min: 1/Max: 88) years. The cause of deafness was congenital in 76.5% of the patients and acquired in 16.8%. The overall rate of complications in the study was 3.7% (n = 97). The minor and major complication rates were 3.0 and 0.7, respectively. Further, while the most common minor complication we encountered was vertigo, the most common major complication was implant extrusion. Conclusion Fixing the cochlear implant receiver-stimulator with the bone-recess technique and sealing the posterior tympanotomy site with a piece of muscle in order to follow surgical rules/medical purpose to avoid any complications. Following the insertion of the electrode into the cochlea, the muscle closure of the cochleostomy site or the round window restores the original anatomy and in order to follow surgical rules/medical purpose to avoid any complications. We have developed this highly effective technique with years of experience and have not had a major surgical complication in 5 years.Publication Metadata only The utilization of Chronic Otitis Media Questionnaire-12 in chronic otitis media with or without cholesteatoma(SPRINGER, 2020) BİNNETOĞLU, ADEM; Demir, Berat; Sahin, Akin; Binnetoglu, Adem; Batman, CaglarObjective This study aimed to compare patients who had chronic otitis media with and without cholesteatoma in terms of the quality of life related to health. Methods The Turkish version of the Chronic Otitis Media Questionnaire-12 (COMQ-12) was completed by totally 100 healthy subjects and 100 patients who had chronic otitis media (COM). The COM group was divided into cholesteatoma and without cholesteatoma [dry tympanic membrane perforation (TMP) and draining ear] groups. Results COMQ-12 score = 3.6 for healthy people. The average scores of dry TMP, draining ear, and cholesteatoma groups were 32.90, 27.34, and 45.95, respectively. A significant difference was between the cholesteatoma and without cholesteatoma groups in total scores (p = 0.001). No difference was found between the groups in age (p = 0.518) and gender (p = 0.975). Conclusion The COMQ-12 could be a useful tool to differentiate chronic otitis media with or without cholesteatoma.Publication Metadata only Comparison of pharyngocutaneous fistula closure with and without bacterial cellulose in a rat model(ELSEVIER SCI LTD, 2018) BİNNETOĞLU, ADEM; Demir, Berat; Sari, Murat; Binnetoglu, Adem; Yumusakhuylu, Ali Cemal; Filinte, Deniz; Tekin, Ishak Ozel; Baglam, Tekin; Batman, Abdullah CaglarObjective: The present study aimed to compare the effects of bacterial cellulose used for closure of pharyngocutaneous fistulae, a complication of total laryngectomy, with those of primary sutures in a rat model. Methods: Thirty female Sprague-Dawley underwent experimental pharyngoesophagotomy and were grouped depending on the material used for pharyngocutaneous fistula closure: group I, which received primary sutures alone, group II, which received bacterial cellulose alone; and group III, which received both. After 7 days, the rats were sacrificed. Pharyngocutaneous fistula development was assessed, the gross wound was inspected, and histological examination was conducted. Results: Pharyngocutaneous fistulae developed in 12 rats (41%) in all: 6 from group I (21%), 4 from group II (14%) and 2 from group III (7%). Conclusion: Fibroblast density and inflammatory cell infiltration were significantly greater in group III than group I. We concluded that bacterial cellulose may be useful for pharyngocutaneous fistula closure. (C) 2017 Elsevier B.V. All rights reserved.Publication Open Access A Challenge for Cochlear Implantation: Duplicated Internal Auditory Canal(2016-10-07) BİNNETOĞLU, ADEM; Binnetoglu, Adem; Baglam, Tekin; Sari, Murat; Gundogdu, Yavuz; Batman, Caglar