Person: GÜMRÜ TARÇIN, BİRSAY
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GÜMRÜ TARÇIN
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BİRSAY
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Publication Metadata only Serum cytokine and T regulatory cell levels in patients with burning mouth syndrome(WILEY, 2008) GÜMRÜ TARÇIN, BİRSAY; Pekiner, Filiz Namdar; Demirel, Guelderen Yamkkaya; Gumru, Birsay; Ozbayrak, SemihBACKGROUND: Burning mouth syndrome is a disorder usually associated with an unexplained, prolonged sensation of burning inside the oral cavity. Although the etiology is unknown, neural and psychologic factors and cytokines may be implicated in the pathogenesis of burning mouth syndrome. The aim of this study was to investigate the relationship between serum cytokine and T regulatory cell levels in patients with burning mouth syndrome with regard to depression and anxiety. METHODS: Thirty patients with burning mouth syndrome and 30 matched controls participated in the study. Serum cytokine levels were measured with cytometric bead array and T regulatory cells were defined as CD4(+)CD25(+)Foxp-3(+) cells by flow cytometry. The level of anxiety and depression were analyzed by means of the Speilberger State-Trait Anxiety Inventory and Zung Self-Rating Depression Scale. Visual analogue scale was used in the quantification of burning levels of patients. RESULTS: Serum IL-2 and TNF-alpha levels were significantly decreased in patients with burning mouth syndrome compared with controls [mean 16.79 +/- 8.70 vs. 37.73 +/- 41.05 pg/ml (P < 0.05) and mean 39.09 +/- 29.40 vs. 70.83 +/- 42.44 pg/ml (P < 0.01) respectively]. CONCLUSIONS: IL-2 and TNF-alpha might play a role in burning mouth syndrome. Burning mouth syndrome may occur as a sign of predisposition to autoimmunity. Presence of low levels of CD28(+) supports the provision that BMS might be a pre-otoimmune disease.Publication Metadata only Farklı yaş gruplarında uygulanmış (UTİ) ve uygulanması gerekli (UGTİ) tedavilerinin karşılaştırmalı olarak değerlendirilmesi(1999-06-21) NAMDAR PEKİNER, FİLİZ MEDİHA; ERÇALIK YALÇINKAYA, ŞEBNEM; DUMLU, ASIM; GÜMRÜ TARÇIN, BİRSAY; NAMDAR PEKİNER F. M., ERÇALIK YALÇINKAYA Ş., DUMLU A., FİŞEKÇİOĞLU E., Çanakçı E., GÜMRÜ TARÇIN B.Publication Metadata only Peripheral dentinogenic ghost cell tumor: Evaluation of clinical, histopathologic and radiological findings: Case report [Periferal dentinojenik hayalet hücreli tümör: Klinik, histopatolojik ve radyolojik bulguların deǧerlendirilmesi](Turkiye Klinikleri, 2013) GÜMRÜ TARÇIN, BİRSAY; Namdar PekIner F., Şener B.C., Gümrü B., Olgaç V., Borahan M.O.The dentinogenic ghost cell tumor is a rare solid variant of the calcifying odontogenic cyst. A 77-year-old man presented with a gingival mass on the alveolar crest mucosa of canine to first premolar of the right mandibular region. After clinical and radiological examination, the prediagnosis was peripheral ossifying fibroma. An incisional biopsy was performed, and the specimen was submitted for histopathologic evaluation. The lesion was characterized histopatholocially by ameloblastoma-like odontogenic epithelial proliferation, presence of ghost cells and dentinoid material. It was finally diagnosed as peripheral dentinogenic ghost cell tumor after excision with a margin of sound bone. In this report, a rare new case is described and the relevant literature is briefly reviewed. © 2013 by Türkiye Klinikleri.Publication Metadata only Muayenehane ve üniversite kliniklerindeki diş hekimlerinin enfeksiyondan korunma yaklaşımlarının karşılaştırılmalı değerlendirilmesi(1999-06-21) ERÇALIK YALÇINKAYA, ŞEBNEM; NAMDAR PEKİNER, FİLİZ MEDİHA; GÜMRÜ TARÇIN, BİRSAY; ERÇALIK YALÇINKAYA Ş., NAMDAR PEKİNER F. M., FİŞEKÇİOĞLU E., Çanakçı E., GÜMRÜ TARÇIN B.