Person: OĞUZ, ESMA
Loading...
Email Address
Birth Date
Research Projects
Organizational Units
Job Title
Last Name
OĞUZ
First Name
ESMA
Name
5 results
Search Results
Now showing 1 - 5 of 5
Publication Open Access Characterization and viability prediction of commercial probiotic supplements under temperature and concentration conditioning factors by NIR spectroscopy(2022-02-01) OĞUZ, ESMA; Aguinaga Bosquez J. P., OĞUZ E., CEBECİ A., Majadi M., Kisko G., Gillay Z., Kovacs Z.The quality of probiotics has been associated with bacteria and yeast strains\" contents and their stability against conditioning factors. Near-infrared spectroscopy (NIRS), as a non-destructive, fast, real-time, and cost-effective analytical technique, can provide some advantages over more traditional food quality control methods in quality evaluation. The aim of our study was to evaluate the applicability of NIRS to the characterization and viability prediction of three commercial probiotic food supplement powders containing lactic acid bacteria (LAB) subjected to concentration and temperature conditioning factors. For each probiotic, 3 different concentrations were considered, and besides normal preparation (25 degrees C, control), samples were subjected to heat treatment at 60 or 90 degrees C and left to cool down until reaching room temperature prior to further analysis. Overall, after applying chemometrics to the NIR spectra, the obtained principal component analysis-based linear discriminant analysis (PCA-LDA) classification models showed a high accuracy in both recognition and prediction. The temperature has an important impact on the discrimination of samples. According to the concentration, the best models were identified for the 90 degrees C temperature treatment, reaching 100% average correct classification for recognition and over 90% for prediction. However, the prediction accuracy decreased substantially at lower temperatures. For the 25 degrees C temperature treatment, the prediction accuracy decreased to nearly 60% for 2 of the 3 probiotics. Moreover, according to the temperature level, both the recognition and prediction accuracies were close to 100%. Additionally, the partial least square regression (PLSR) model achieved respectable values for the prediction of the colony-forming units (log CFU/g) of the probiotic samples, with a determination coefficient for prediction ((RPr)-Pr-2) of 0.82 and root mean square error for prediction (RMSEP) of 0.64. The results of our study show that NIRS is a fast, reliable, and promising alternative to the conventional microbiology technique for the characterization and prediction of the viability of probiotic supplement drink preparations.Publication Open Access Biochemical relationship between glucose-6-phosphate dehydrogenase deficiency and covıd-19 and effects of glutathione supplements(2022-01-01) OĞUZ, ESMA; CEBECİ, AYBİKE; OĞUZ E., CEBECİ A.Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the pentose phosphate pathway involved in the production of the reduced form of nicotinamide adenine dinucleotide phosphate (NADPH). One of the most common inherited enzyme abnormalities is G6PD deficiency. G6PD enzyme deficiency facilitates human coronavirus infection due to glutathione (GSH) depletion. Depletion of glutathione due to blockage of the pentose phosphate pathway can hardly preserve the oxidative and anti-oxidative balance. GSH protects the body from the harmful effects of oxidative damage from excess reactive oxygen radicals. Levels of GSH, the key antioxidant protector in all tissues, could be critical in quenching the exacerbated inflammation that triggers organ failure in the new coronavirus disease (COVID-19). Since several amino acids intersect with the GSH pathway, changing the concentrations of these amino acids directly or indirectly can alter cellular GSH homeostasis. Supplementation of amino acids and as well as the implementation of diet strategies offer safe and non-invasive strategies for improving GSH status and protect the body from oxidative stress in various diseases and conditions. The purpose of this review is to examine the biochemical relationship between G6PD deficiency and COVID-19 and the effect of GSH on this disease.Publication Metadata only The relationship between nutrition and Meniere's disease(ELSEVIER SCI LTD, 2021) CEBECİ, AYBİKE; Oguz, Esma; Cebeci, Aybike; Gecici, Cennet ReyyanMeniere's disease is an inner ear disease with attacks characterized by ear fullness, tinnitus, fluctuant sensorineural hearing loss and vertigo. Although pathophysiology of the disease is not fully known, endolymphatic hydrops are believed to play a role. Although there is no certain treatment procedure for Meniere's disease, some treatments are applied to prevent attacks, to treat the symptoms that occur during the attacks, and to prevent the permanent effects of the symptoms on the hearing and balance system. Lifestyle changes, dietary modifications, diuretics, vasodilator corticosteroids, intratympanic steroids, surgical methods are some of these treatment methods. Dietary modification includes a low sodium diet, a reduction in daily alcohol and caffeine intake, a gluten-free diet, and a new dietary approach to specially processed grains, all of which are first-line treatments. The goal of this review article is to examine the relationship between MD and dietary intervention, which is frequently used in the prevention and treatment of MD attacks. (C) 2021 Oto-Rhino-Laryngological Society of Japan Inc. Published by Elsevier B.V. All rights reserved.Publication Metadata only Okul temelli toplum çalışmaları kapsamında yürütülen beslenme faaliyetleri: Soyaç Modeli(2021-06-02) AKTAÇ, ŞULE; KUNDAKÇI, SİMAY; OĞUZ, ESMA; AKTAÇ Ş., BADEMCİ H. Ö., KUNDAKÇI S., OĞUZ E., KAYIKÇI K., GÜLER B., BAYKAN M., GÜNEŞ F. E.Publication Open Access Non-alcoholic fatty liver disease: pathogenesis and assessing the impact of dietary bioactive compounds on the liver(2024-05-31) OĞUZ, ESMA; OĞUZ E., Karakoyun B.Non-alcoholic fatty liver disease (NAFLD) is a pathological condition ranging from simple steatosis to non-alcoholic steatohepatitis, cirrhosis, and liver cancer. NAFLD is a complex disease mediated by metabolic, environmental, and genetic mechanisms. Many factors such as insulin resistance, lipotoxicity, inflammation, mitochondrial dysfunction, endoplasmic reticulum stress, circadian rhythm, genetics, epigenetics, dietary factors, and gut microbiota play a crucial role in the pathogenesis of NAFLD. Lifestyle changes such as healthy diet, physical activity, avoiding alcohol and smoking are involved in the NAFLD treatment. Dietary bioactive compounds including curcumin, resveratrol, catechins, quercetin, sulforaphane, epigallocatechin-3-gallate, alkaloids, vitamins, and peptides have many health promoting effects such as antioxidant, anti-inflammatory, antihypertensive, chemopreventive, and hepatoprotective. In this review, the pathophysiology of NAFLD and the effects of dietary bioactive compounds on this disease will be discussed in detail with updated information.