Person: AY, NADİYE PINAR
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AY
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NADİYE PINAR
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Publication Open Access The Turkish Language and Psychometric Validation of the Bladder Control Self-assessment Questionnaire Evaluating the Lower Urinary Tract Dysfunction(GALENOS YAYINCILIK, 2020-12-01) AY, NADİYE PINAR; Hamarat, Mustafa Bilal; Tarhan, Fatih; Can, Utku; Sahlam, Erkin; Ay, PinarObjective: The aim of this study was to develop and validate the Turkish version of the Bladder Control Self-assessment Questionnaire (B-SAQ). Materials and Methods: B-SAQ that comprises two parts and four questions in each section was translated into Turkish, followed by a back-translation into English. The study included 79 and 49 women who were admitted to the urology outpatient clinic with and without complaints of lower urinary tract symptom (LUTS), respectively. Turkish B-SAQ questionnaire was filled for the second time by 67 patients after a two week interval for test-retest correlation. All patients filled the Turkish B-SAQ form, International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) and Overactive Bladder Screener (OAB-V8) questionnaire. Results: The Cronbach alpha value for B-SAQ was 0.868. Reliability of the test/retest was found to be 0.860 (p<0.001). There were statistically significant differences in B-SAQ scores between the controls and patients (p<0.001). Convergent validity analyzes with ICIQ-SF and OAB-V8 (respectively r=0.61 and r=0.44, p<0.001). The total B-SAQ cut-off score was determined as 7. The sensitivity and specificity of B-SAQ were 96% in women with LUTS. Conclusion: Turkish version of B-SAQ is a valid and reliable questionnaire to evaluate the symptoms and disorders of patients with LUTS.Publication Metadata only Are home sleep studies useful in diagnosing obstructive sleep apnea in children with down syndrome?(WILEY, 2019) KARADAĞ, BÜLENT TANER; Ikizoglu, Nilay Bas; Kiyan, Esen; Polat, Beldan; Ay, Pinar; Karadag, Bulent; Ersu, RefikaIntroduction and Aim Obstructive sleep apnea syndrome (OSAS) is frequent in children with Down syndrome (DS) and polysomnography (PSG) is recommended for all children with DS. However PSG is not always available and alternative diagnostic methods are needed. The aim of the study was to evaluate the feasibility and validity of home polygraphy (HPG) in children with DS. Methods A national DS association was contacted and children aged 6 to 18 years who accepted to participate were recruited. Otorhinolaryngologic evaluation, in-lab PSG and HPG were performed. OSAS was diagnosed by PSG with an apnea-hypopnea index (AHI) more than or equal to 1. OSAS severity was classified as moderate-to-severe if AHI was more than or equal to 5. Receiver operating characteristic curves were calculated for HPG using PSG as the gold standard. Results Nineteen children (12 girls) completed the study. Median age was 11.3 years. Demographic and clinical characteristics were similar in children with and without OSAS. Eighty-nine percent of HPG studies were technically acceptable at the initial night and the success rate was 100% when two failed studies were repeated. PSG revealed OSAS in six (32%) children, two had mild and four had moderate-to-severe OSAS. All four patients with moderate-to-severe OSAS diagnosed with PSG have been diagnosed with the same severity on HPG. HPG had 100% sensitivity and 83% specificity when AHI >= 3 was set as diagnostic criteria. Conclusion HPG is a feasible and reliable test of OSAS in children with DS and may be useful in diagnosis and treatment of patients with moderate-to-severe OSAS in this patient group.Publication Metadata only Association of sleep duration with socio-economic status and behavioural problems among schoolchildren(WILEY, 2011) TOPUZOĞLU, AHMET; Arman, Ayse Rodopman; Ay, Pinar; Fis, Nese Perdahli; Ersu, Refika; Topuzoglu, Ahmet; Isik, Ugur; Berkem, MeralAim: In this population-based study, we aimed to determine the total sleep duration (TSD), its association with socio-economic status (SES) and behavioural symptoms among schoolchildren. Methods: A cross-sectional study was performed among schoolchildren in Istanbul. A structured questionnaire evaluating the sleep schedule variables was filled out by their parents. SES was determined according to the Turkish SES scale. Results: The mean age of 2669 children was 8.2 +/- 2.4 years, and 51% of the students were girls. The mean TSD was 10.20 +/- 1.04, and the mean bedtime was 21.57 +/- 0.56 (both in hours, minutes +/- SD). Boys tended to go bed later (p = 0.004) and slept less than girls (p = 0.02). The duration of sleep disruptions increased (p < 0.001), whereas TSD decreased with age (p < 0.001). Multiple linear regression revealed that waking time and TSD decreased significantly (p < 0.05) with higher SES among both girls and boys. Sleep fragmentation was associated with habitual snoring, parasomnias, daytime sleepiness and conduct symptoms. Conclusion: Decreased total sleep duration is more prominent in boys, older children and children among higher socio-economic status. Insufficient sleep attributed to shortened total sleep duration by age and higher socio-economic status might have a negative effect on both sleep hygiene and psychological well-being in schoolchildren.Publication Metadata only Effect of Occupation and Smoking on Respiratory Symptoms in Working Children(WILEY, 2009) ÖZEN, AHMET OĞUZHAN; Cakir, Erkan; Uyan, Zeynep S.; Varol, Nezih; Ay, Pinar; Ozen, Ahmet; Karadag, BuIent; Ersu, Refika; Karakoc, Fazilet; Daglil, ElifObjectives To compare the respiratory symptoms and the lung function of children who work in different occupational groups. Methods The study was performed among children attending vocational training centers. The participants were evaluated in six different occupation groups. Chronic cough, wheezing and shortness of breath were evaluated by questionnaire. The association of independent variables with the respiratory symptoms was investigated through both univariate and multivariate methods. Results Among 642 children, 534 were males: the mean age was 17.7 +/- 1.0 years. Using an internal reference group, the odds ratios of chronic cough were significantly higher in the lathe (OR: 2.0, 95%CI: 1.07-3.74), coiffure (OR: 1.94. 95%CI: 1.01-3.70), and electricity-construction (OR: 2.63, 95%CI: 1.06-6.54) groups after adjustment for smoking, age, gender, and work characteristics. There were no significant differences in spirometric values between occupational groups in either smoking or non-smoking males. In non-smoking females, median values of FEV1 (P: 0.046), PEF (P: 0.0005) and FEF25-75% (P: 0.019) were lower in the textile compared to the coiffure group. There was no significant association between the total working time and spirometric values. There was no statistically significant relationship between the work-related factors and the smoking status. Conclusions The prevalence of chronic cough was higher in the lathe, coiffure, and electricity-construction groups and pulmonary function tests were lower in the non-smoking textile female group. Working children should be screened for respiratory symptoms and disease. Am. J. Ind. Med. 52:471-478, 2009. (c) 2009 Wiley-Liss, Inc.Publication Open Access Evaluation of mucosal status in the follow-up of pediatric patients with celiac disease: the role of serology(2022-09-01) AY, NADİYE PINAR; ERTEM ŞAHİNOĞLU, DENİZ; ÇELİKEL, ÇİĞDEM; Sengul O. K., Akkelle B. S., Ay P., Volkan B., Tutar E., Celikel Ç., Ertem D.Recent guidelines suggest non-biopsy serology-based approach for the diagnosis of celiac disease; however, there is no evidence-based data regarding noninvasive follow-up of mucosal healing. The aim of this study is to investigate the efficacy of serology in reflecting mucosal status in the follow-up of pediatric patients with celiac disease. This is a validation study conducted at a university hospital. Patients who had biopsy proven celiac disease (Marsh III) at diagnosis, and had been followed-up for at least 12 months, were prospectively evaluated with duodenal biopsies. tTG-IgA and EMA tests were performed on the day of endoscopy. One hundred four patients with a mean age of 7.4 +/- 4.02 years were included in the study. The sensitivity and specificity of tTG-IgA were 85.2% and 61% respectively, with a high negative predictive value (NPV) of 92.2% but a very low positive predictive value (PPV) of 43.4%. We found that a cutoff value of 68.5 U/mL for tTG-IgA had a sensitivity, specificity of 85.2% and 85.7% respectively. The AUC was 0.891. The sensitivity and specificity of EMA was 77.8% and 87% respectively, with a high NPV of 91.8% but low PPV of 67.7%.Publication Metadata only Rubella seroprevalence among first-grade primary school students in a district in Istanbul, Turkey(W B SAUNDERS CO LTD, 2006) TOPUZOĞLU, AHMET; Ay, P; Topuzoglu, A; Korukluoglu, G; Cali, SObjectives Rubella vaccination is not included in the national immunization programme of Turkey. However, it is on the market and is recommended, mainly by the private sector, at the age of 12-15 months. Introduction of the rubella vaccine without achieving high coverage has the risk of shifting the mean age of rubella infection among the unvaccinated population to reproductive ages. The aim of this study was to evaluate the seroprevalance of rubella and the factors associated with seropositivity among primary school students in Umraniye, a district of Istanbul. Methods: Blood samples were collected from 489 students in 70 primary schools of Umraniye. Parents completed a concise questionnaire assessing sociodemographic characteristics and measles, mumps and rubella vaccination status. Results: Among the students screened, 163 (33.3%, 95% confidence intervals 29.2-37.7%) were susceptible to rubella. When sociodemographic variables were evaluated, paternal education was the only variable associated with seronegativity. As the level. of paternal education increased, seronegativity rates decreased. This finding may suggest that rubella vaccination is practiced more commonly among children whose fathers are better educated. Conclusions: Surveillance and control of rubella and congenital rubella syndrome must be set as public health priorities in Turkey, particularly given that rubella vaccination is practiced partially in the country. (c) 2005 The Royal Institute of Public Health. Published by Elsevier Ltd. All rights reserved.Publication Open Access Estimating high-risk cannabis and opiate use in Ankara, Istanbul and Izmir(WILEY, 2017-09) AY, NADİYE PINAR; Kraus, Ludwig; Hay, Gordon; Richardson, Clive; Yargic, Ilhan; Ilhan, Mustafa Necmi; Ay, Pinar; Karasahin, Fusun; Pinarci, Mustafa; Tuncoglu, Tolga; Piontek, Daniela; Schulte, BerndIntroduction and Aims. Information on high-risk drug use in Turkey, particularly at the regional level, is lacking. The present analysis aims at estimating high-risk cannabis use (HRCU) and high-risk opiate use (HROU) in the cities of Ankara, Istanbul and Izmir. Design and Methods. Capture-recapture and multiplier methods were applied based on treatment and police data stratified by age and gender in the years 2009 and 2010. Case definitions refer to ICD-10 cannabis (F.12) and opiate (F.11) disorder diagnoses from outpatient and inpatient treatment records and illegal possession of these drugs as recorded by the police. Results. High-risk cannabis use was estimated at 28 500 (8.5 per 1000; 95% confidence interval 7.3-10.3) and 33 400 (11.9 per 1000; 95% confidence interval 10.7-13.5) in Ankara and Izmir, respectively. Using multipliers based on capture-recapture estimates for Izmir, HRCU in Istanbul was estimated up to 166 000 (18.0 per 1000; range: 2.8-18.0). Capture-recapture estimates of HROU resulted in 4800 (1.4 per 1000; 95% confidence interval 0.9-1.9) in Ankara and multipliers based on these gave estimates up to 20 000 (2.2 per 1000; range: 0.9-2.2) in Istanbul. HROU in Izmir was not estimated due to the low absolute numbers of opiate users. Discussion and Conclusions. While HRCU prevalence in both Ankara and Izmir was considerably lower in comparison to an estimate for Berlin, the rate for Istanbul was only slightly lower. Compared with the majority of European cities, HROU in these three Turkish cities may be considered rather low.Publication Metadata only Validation of the Wexner scale in women with fecal incontinence in a Turkish population(SPRINGER LONDON LTD, 2011) AY, NADİYE PINAR; Cam, Cetin; Selcuk, Selcuk; Asoglu, Mehmet Resit; Tug, Niyazi; Akdemir, Yesim; Ay, Pinar; Karateke, AtesIntroduction and hypothesis The main aim of this study was to validate the Turkish translated version of the Wexner scale. Methods After establishing the test-retest reliability and internal consistency of the Turkish version of Wexner scale on 31 patients, total and subscale scores and anal manometric measurements of 60 participants were performed. Correlation between Wexner scale scores and manometric measurement values were analyzed and those values of patients with or without anal incontinence symptoms were compared. Results Of the 60 participants, 47 (78%) showed no signs or symptoms of anal incontinence. Wexner scale showed a high internal consistency (Cronbach's alpha=0.816). Total and each subscale score of Wexner scale showed strong correlation with resting and maximal squeeze pressures and between each other (p<0.005). The pressure values were significantly less in asymptomatic patients compared to patients with any degree of symptoms (p<0.05). Conclusion The Turkish translated version of the Wexner scale is a reliable, consistent, and valid instrument to evaluate anal functions in women with anal incontinence for Turkish speaking women. Total and subscale scores of the Wexner scale and anal manometric measurements showed significant correlation.Publication Metadata only Effect of Night Symptoms and Disease Severity on Subjective Sleep Quality in Children With Non-Cystic-Fibrosis Bronchiectasis(WILEY, 2011) KARADAĞ, BÜLENT TANER; Erdem, Ela; Ersu, Refika; Karadag, Bulent; Karakoc, Fazilet; Gokdemir, Yasemin; Ay, Pinar; Akpinar, Ihsan Nuri; Dagli, ElifBackground: Night-time symptoms and hypoxemia during sleep may affect sleep quality in children with chronic lung disease such as bronchiectasis. Poor sleep quality may impair growth, learning, and emotional development of children. Our aim was to assess the sleep quality and associated factors in children with non-cystic fibrosis bronchiectasis. Methods: Fifty-four patients with bronchiectasis and age-matched controls were included to the study. Pittsburgh Sleep Quality Index (PSQI) and Pediatric Sleep Questionnaire (PSQ) were used to evaluate sleep quality and presence of sleep disordered breathing. A global sum of 5 or more according to PSQI indicated a poor sleep quality. A cut-off value of 0.33 in PSQ was used to identify pediatric sleep disordered breathing. Association between PSQI, pulmonary function tests, symptoms and HRCT scores were evaluated. Results: Thirty-seven percent of patients with bronchiectasis and 17% of patients in the control group had poor sleep quality (P < 0.05). Patients with sputum and wheezing had poorer sleep scores (P = 0.003 and P = 0.005). The association of wheezing and breathlessness during night time with sleep quality tended to be significant (P = 0.05). Twenty-two percent of patients with bronchiectasis and 9% of controls had sleep disordered breathing (P = 0.003). Bronchiectasis patients who snored had poorer sleep quality (P < 0.001) and patients with wheezing had significantly higher rate of snoring (P = 0.04). Children with worse HRCT scores also had worse sleep quality (r = 0.28, P = 0.04). Conclusions: Patients with bronchiectasis have disturbed sleep associated with severity of disease. Night symptoms increase the risk of poor sleep quality. Sleep disordered breathing and sleep quality should be assessed in these patients. Pediatr Pulmonol. 2011; 46:919-926. (C) 2011 Wiley-Liss, Inc.Publication Open Access Are neighborhood characteristics associated with physical activity levels among school children?(2023-01-01) AY, NADİYE PINAR; HIDIROĞLU, SEYHAN; Kaya G., AY N. P., HIDIROĞLU S.Objective: The objective of this study was to determine the prevalence of insufficient physical activity (IPA) and neighborhood characteristics associated with it, among school children. The impact of sociodemographic characteristics and ownership of electronic devices on physical activity (PA) were also evaluated. Materials and Methods: This was a cross-sectional study carried out among 5-7th grade students attending schools and their parents. IPA was defined as having moderate-vigorous activity for 0.05).Conclusion: The prevalence of IPA is alarmingly high among school children. The impact of neighborhood characteristics on PA might be obscured since both variables were measured subjectively. Devices related information/communication technologies increase IPA; we need to find novel ways to use these devices for PA promotion. There is also a need to increase structured PA opportunities.