Person: GÜL, FETHİ
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GÜL
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FETHİ
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Publication Metadata only Terapötik Hipotermi Sonrası Gelişen Enfeksiyonların Öngörülmesinde Hematoloji Parametrelerinin Kullanımı(2017-10-29) HAKLAR, GONCAGÜL; GÜL, FETHİ; KASAPOĞLU, UMUT SABRİ; CİNEL, İSMAİL HAKKI; GÜL F., ÇEVLİK T., ARSLANTAŞ M. K., KASAPOĞLU U. S., HAKLAR G., CİNEL İ. H.Publication Metadata only Histopathological evaluation of post-mortem pulmonary specimens excised from ICU patients with COVID-19: Do we know what we do not know(2023-05-06) ERMERAK, NEZİH ONUR; BOZKURTLAR, EMİNE; KOCAKAYA, DERYA; GÜL, FETHİ; KARAKURT, SAİT; ERMERAK N. O., BOZKURTLAR E., KOCAKAYA D., GÜL F., KARAKURT S., Cinel I.Publication Metadata only The initial resuscitation of septic shock(W B SAUNDERS CO-ELSEVIER INC, 2020) GÜL, FETHİ; Cinel, Ismail; Kasapoglu, Umut S.; Gul, Fethi; Dellinger, R. PhillipSeptic shock is the most severe form of sepsis, characterized by (a) persistent hypotension despite fluid resuscitation and (b) the presence of tissue hypoperfusion. Delays in the diagnosis and initiation of treatment of septic shock is associated with increasing risk for mortality. Early and effective fluid resuscitation and vasopressor administration play a crucial role in maintaining tissue perfusion in septic shock patients. A low diastolic arterial pressure (DAP) correlates with severity of arteriolar vasodilation, compromises left ventricle oxygen supply and can be used for identifying septic shock patients thatwould potentially benefit fromearlier vasopressor therapy. Controversy currently exists as to the balance of fluids and vasopressors to maintain target mean arterial pressure. The aim of this article is to review the rationale for fluid resuscitation and vasopressor therapy and the importance of both mean and diastolic blood pressure during the initial resuscitation of the septic shock. We relate our personal prescription of balancing fluids and vasopressors in the resuscitation of septic shock. (c) 2020 Elsevier Inc. All rights reserved.Publication Metadata only Treatment approach of cerebral ischemia after revascularization surgery of moyamoya disease: Case report(2019-05-05) GÜL, FETHİ; KASAPOĞLU, UMUT SABRİ; CİNEL, İSMAİL HAKKI; GÜL F., KABADAYI F., KASAPOĞLU U. S., CİNEL İ. H.Publication Metadata only Lazer cerrahisi sırasında gelişen trakeobronşial inhalasyon yanığı- olgu sunumu(2017-10-29) KASAPOĞLU, UMUT SABRİ; GÜL, FETHİ; YUMUŞAKHUYLU, ALİ CEMAL; UMUROĞLU, TÜMAY; CİNEL, İSMAİL HAKKI; KASAPOĞLU U. S., GÜL F., ARSLANTAŞ M. K., YUMUŞAKHUYLU A. C., YAMANSAVCI E., UMUROĞLU T., CİNEL İ. H.Publication Metadata only Türkiye’de yoğun bakımlarda yeni tip koronavirus nedeniyle hospitalize edilmiş olgularda aşılama ve varyant sıklığı ile aşılamanın 28-günlük mortaliteye etkisi(2022-03-20) KASAPOĞLU, UMUT SABRİ; GÜL, FETHİ; GÜL F., KASAPOĞLU U. S., SABAZ M. S., AY P., DORUK OKTAY B., ÇALIŞKAN G., DEMİR N., SAYAN İ., KABADAYI F., ALTUNTAŞ G., et al.Publication Metadata only Evaluation of the Diagnostic Value of Cell Population Data in Sepsis in Comparison to Localized Infection, Chronic Inflammation, and Noninfectious Inflammation Cases.(2022-09-22) DİRESKENELİ, RAFİ HANER; KAYA, ÖZLEM; GÜL, FETHİ; İNANÇ, GÜZİDE NEVSUN; İLKİ, ZEYNEP ARZU; ŞİRİKÇİ, ÖNDER; HAKLAR, GONCAGÜL; Çevlik T., Kaya Ö., Gül F., Turkal R., İnanç N., Direskeneli H., İlki A., Şirikçi Ö., Haklar G., Cinel İ.Introduction Sepsis, defined as an increase of 2 points or more in the sequential organ failure assessment score, is a life-threatening organ dysfunction caused by the dysregulated host response to infection. Volume-conductivity-scatter (VCS) parameters of cell counters which are known as cell population data (CPD) have been suggested to be beneficial in diagnosing sepsis. We aimed to evaluate the diagnostic value of CPD parameters in sepsis in comparison to nonsystemic infection cases (NSI) and non-infectious acute and chronic inflammatory conditions. Materials and Methods We prospectively included four groups of patients” data: sepsis (n = 66), localized infection (pneumonia, n = 59), chronic inflammation (rheumatoid arthritis, n = 92) and noninfectious inflammation (coronary artery bypass graft operation, n = 56) groups, according to their clinical status and laboratory results. Samples for cell counting and serum markers were collected on the same day of culture collection. VCS parameters were measured by Unicel DxH800 Coulter Cellular Analyzer (Beckman Coulter, USA). Results Mean neutrophil volume (MN-V-NE), was highest in the sepsis group [155(149-168)] compared to the localized infection [148(140-158)], chronic inflammation [144.5(142-149)] and noninfectious inflammation [149(145.2-153.7)] (P = 0.001, P < 0.001, P < 0.001, respectively). Neutrophil volume SD (SD-V-NE) was higher in the sepsis [21(18.8-23.7)], significantly differentiating sepsis from other groups. The area under curves of procalcitonin and hs-C-reactive protein were 0.846 and 0.837, respectively, in the receiver-operating characteristic curves (ROC) . CPD combinations, (SD-V NE + SD-V LY + SD-V MO), (SD-V NE + SD-V MO), and (MN-V NE + SD-V NE + SD-C LY + SD-V MO) had greater AUC values than procalcitonin’s. Conclusion VCS parameters might be promising for differentiating sepsis and non-sepsis cases. Additionally, obtaining these data routinely makes their prospects promising without any additional cost and time.Publication Metadata only Transmission route of acinetobacter baumannii infection in earthquake survivors(2023-05-07) GÜL, FETHİ; Ciğeroğlu A., Bilir A., Kutlu Ç., Sabaz M. S., Gül F.Publication Metadata only Hemoadsorption therapy for earthquake victims with crush injury(2023-05-07) GÜL, FETHİ; Kandemir E., Kutlu Ç., Bilir A., Gül F.Introduction: Recently, a huge earthquake struck south-eastern Turkey causing the death of tens of thousands of people. In this case report, we share our experience of usage of extracorporeal hemoadsorption filter in two patients with crush injury and acute kidney injury.Case: A 59 year-old male patient was under rubble for 24 hours with his left leg trapped. The patient was transported to our hospital on the second day after the incident. At the admission, he had cardiac arrest with the rhythm of ventricular fibrillation. He was defibrillated two times and resuscitated for 30 minutes. Serum potassium, phosphorus levels were 8.5 mEq/L, 9 mg/dL respectively. Intravenous calcium,dextrose+insulin was given immediately and continuous renal replacement therapy was started. Initial creatine kinase (CK) level was 82000 U/L. He has undergone an urgent surgery for amputating his left leg which was necrotic. The day after his admission, extracorporeal hemoadsorption therapy (JAFRON-HA330) was started five hours a day for five consecutive days. CK levels gradually decreased to 60187-46852-16954-11600 U/L in daily order. Vasopressors were stopped on the third day of admission. A 32-year-old male patient had been extricated after 24 hours of entrapment. He had fifteen minutes of CPR following a cardiac arrest from hyperkalemia. Initial levels of CK, potassium, phosphorus were 72116 U/L, 6.5 mEq/L, 7.3 mg/dL respectively. CRRT with hemadsorption filter (Jafron® HA330) was started. CK levels gradually decreased to levels of 64271-35670-25441-12475-10469 U/L in daily order. He got free of vasopressors on the third day and extubated on the fourth day of admission.Discussion: Crush injury is a hyperinflammatory state with circulating cytokines causing multisystemic organ dysfunctions. Hemoadsorption techniques may adsorb molecules which potentially play a role during pathogenesis of rhabdomyolysis.The use of hemoadsorption therapy in our patients with severe traumatic rhabdomyolysis was associated with a significant reduction in plasma concentrations CK so it is a potentially attractive adjunctive treatment for this condition.Publication Metadata only The role of the thrombolytic therapy in acute ıschemic stroke: Two case reports(2023-05-07) GÜL, FETHİ; Bilir A., Şahin N. O., Oktay B. D., Gül F.