Person: ERYÜKSEL, SEMİHA EMEL
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ERYÜKSEL
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SEMİHA EMEL
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Publication Open Access The role of procalcitonin as a biomarker for acute pulmonary exacerbation in subjects with cystic fibrosis and non-cystic fibrosis bronchiectasis(2022-01-01) KOCAKAYA, DERYA; ARIKAN, HÜSEYİN; ERYÜKSEL, SEMİHA EMEL; CEYHAN, BERRİN; Mammadov F., Olgun Yildizel S., Kocakaya D., ARIKAN H., Cinar C., Eryuksel E., CEYHAN B.Objective: Patients with cystic fibrosis (CF) and non-CF bronchiectasis are prone to exacerbations of pulmonary infections. C-reactive protein (CRP) and procalcitonin (PCT) are inflammatory markers. The aim of this study is to evaluate the role of CRP and PCT on exacerbations of CF and non-CF bronchiectasis. Patients and Methods: The medical records of 18 CF (52 hospitalizations) and 20 non-CF bronchiectasis patients (51 hospitalizations) were reviewed retrospectively. CRP, PCT levels and, white blood cell (WBC) counts on admission and follow-up were evaluated. Results: C-reactive protein levels correlated with PCT levels on admission in all patients. Baseline PCT levels were markedly higher (>0.5µg/L) in 12% of CF and 10% of non-CF bronchiectasis patients, however, baseline CRP values were markedly higher (>5mg/L) in 96% of CF and non-CF bronchiectasis patients (p=0.760 and p=0.100, respectively). Baseline CRP and PCT levels were positively correlated with hospitalization length (r=0.501, p=0.001 and r=0.289, p=0.04, respectively) in CF patients, but not in non-CF bronchiectasis. Conclusion: Our study shows the potential utility of these biomarkers to determine the severity of the exacerbation particularly predicting hospitalization length in CF patients. Both biomarkers could be able to guide antibiotic treatment of infective exacerbations in CF and non-CF bronchiectasis patients.Publication Open Access Reliability and validity of the Turkish translation of the beliefs about medicines questionnaire (bmq-t) in patients with behçet’s disease(2018-10-01) ARIKAN, HÜSEYİN; KARAKURT, SAİT; ERYÜKSEL, SEMİHA EMEL; ARIKAN H., Duman D., Kargın F., ERGİN G., Horne R., KARAKURT S., ERYÜKSEL S. E.Publication Open Access Burden, depression and fatigue in caregivers of lung transplantation candidates(2023-01-01) OLGUN YILDIZELİ, ŞEHNAZ; TUFAN ÇİNÇİN, ASLI; ARIKAN, HÜSEYİN; ERYÜKSEL, SEMİHA EMEL; OLGUN YILDIZELİ Ş., Tufan Cincin A., ARIKAN H., Eryuksel E.Objective: A great deal of social support is often provided by the caregiver of the patient. The purpose of this study is to evaluate the burden, fatigue and depression of the primary caregiver of patients with pulmonary transplantation candidates.Patients and Method: The primary caregivers of patients who were admitted to our hospital\"s pulmonary transplant outpatient clinic with end-stage pulmonary disease and no definite contraindications for transplantation, were included in the study. Zarit Burden Scale, Beck Depression Inventory and Short-Form (SF)-36 - Vitality questionnaires were applied to participants.Results: Thirty-nine patients and their caregivers were evaluated. Caregivers experienced low levels of depression. Mean score for Beck Depression Inventory was 12.7 +/- 10.1. Caregivers generally experienced medium levels of burden. Mean score for Zarit Burden Scale was 26.9 +/- 14.2. Majority of caregivers experienced clinically significant fatigue. Mean score for SF-36 - Vitality was 61 +/- 16.7. Zarit Burden Scale scores and Beck Depression Inventory scores showed a statistically significant positive correlation (r:0.962 p<0.01). Conclusion: Increased burden of caregivers of lung transplant candidates was associated with depression and fatigue. The presence of depressive symptoms is noteworthy even in the mild to moderate levels of burden. Supporting caregivers, has a great importance in terms of patient care and quality.