Person: GÜNDÜZ, OSMAN HAKAN
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GÜNDÜZ
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OSMAN HAKAN
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Publication Open Access Pain Relief due to Transsacrococcygeal Ganglion Impar Block in Chronic Coccygodynia: A Pilot Study(OXFORD UNIV PRESS, 2015-07) GÜNDÜZ, OSMAN HAKAN; Gunduz, Osman Hakan; Sencan, Savas; Kenis-Coskun, OzgeObjectiveCoccygodynia is a distressing condition that presents with pain around the coccyx. Impar (Walther) ganglion is a sympathetic ganglion located at the end of lumbosacral sympathetic chain. The objective of this study is to share our results and follow up of 34 ganglion impar blocks in 22 patients. DesignRetrospective pilot study. SettingInterventional Pain Clinic in the Department of Physical Medicine and Rehabilitation in a university hospital. SubjectsTwenty-two patients with coccygodynia who did not respond to conservative treatment and then presented to interventional pain clinic of a PM&R department in a university hospital MethodsPain was evaluated via 10-cm visual analog scale (VAS). VAS values were obtained before, 1 hour and 3 weeks after injection and during this study was conducted. ResultsFor achieving at least 50% relief of pain, the success rate of a first injection was 82%, but accounted for three technical failures. In patients with a successful outcome, relief lasted for a median duration of 6 months. Relief was reinstated for a median period of 17 months by a second injection in nine patients who presented for repeat treatment. No relief was achieved in two of these patients when they presented for a third treatment. ConclusionsGanglion impar block appears to be effective in patients who have coccygodynia resistant to conservative therapy, with high success rates and prolonged duration of effect. Controlled studies are required to reveal the mechanism of this effect.Publication Open Access Reply to the Letter by J. Hambraeus, 'Ganglion Impar Blocks for More than Coccygodynia'(OXFORD UNIV PRESS, 2016-03-15) GÜNDÜZ, OSMAN HAKAN; Gunduz, Osman Hakan; Sencan, Savas; Kenis-Coskun, OzgePublication Metadata only Ganglion Impar block improves neuropathic pain in coccygodynia: A preliminary report(ELSEVIER URBAN & PARTNER SP Z O O, 2018) GÜNDÜZ, OSMAN HAKAN; Sencan, Savas; Kenis-Coskun, Ozge; Demir, Fatma Gul Ulku; Cuce, Isa; Ercalik, Tulay; Gunduz, Osman HakanAim of the study: To define the effectiveness of ganglion Impar block in improving neuropathic pain. Materials and methods: Patients who had pain around the coccyx for more than three months and did not respond to conservative treatment were included in this study. All the patients underwent fluoroscopy guided transsacrococcygeal ganglion Impar block with injecting 3 mL of 0.5% bupivacaine, 2 mL saline, and 1 mL (40 mg) of methylprednisolone. Patients were evaluated with visual analog scale (VAS) for pain, Leeds assessment of neuropathic symptoms and signs scale (LANSS) for neuropathic pain, Beck depression Inventory (BDI) for mood and Short-form 12 (SF-12) for quality of life before, 1 month 3 months and 6 months after the injection. Patients' painless sitting duration was also recorded. Results: A total of 28 patients were included in the final analyses. VAS and LANSS scores improved significantly throughout the follow-up periods. BDI scores also improved while SF-12 scores did not show significant changes. Painless sitting period of the patients' improved significantly. Conclusions: Ganglion Impar block is effective in decreasing the neuropathic component of chronic coccygodynia. This improves painless sitting in patients but its reflections on quality of life is not clear. (C) 2018 Polish Neurological Society. Published by Elsevier Sp. z o.o. All rights reserved.Publication Metadata only The effect of vitamin D replacement on spinal inhibitory pathways in women with chronic widespread pain(PERGAMON-ELSEVIER SCIENCE LTD, 2020) AKYÜZ, GÜLSEREN DERYA; Kenis-Coskun, Ozge; Giray, Esra; Gunduz, Osman Hakan; Akyuz, GulserenVitamin D replacement helps in pain reduction in patients with chronic widespread pain (CWP). But the current literature lack studies that investigate its mechanism. Cutaneous silent period (CSP) is the electrophysiologic analog of the spinal inhibitory pathways and an objective method to document their involvement. This study aims to show if vitamin D replacement has an effect on the spinal inhibitory pathways through CSP parameters. Female patients who have CWP with vitamin D deficiency were included. Patients received an 8-week replacement therapy of vitamin D. Patients' pain were evaluated using the visual analog scale (VAS) and Leeds assessment of neuropathic symptoms and signs pain scale (LANSS). Quality of life with Nottingham Health Profile (NHP) and CSP parameters were also recorded before and after treatment. A total of 51 patients were included in the final analyses. The mean age of the patients was 44.3 +/- 12.7 (minimum 18-maximum 65). Mean symptom duration was 13.1 +/- 6.7 (minimum3-maximum 24) months. Patients' mean BMI was 21.6 +/- 3.9 (minimum 18.0 maximum 29.1). Patients' median VAS and LANSS scores decreased significantly (p < 0.01) and NHP scores improved significantly in all subsets (p < 0.01). Vitamin D replacement did not significantly change CSP latency and duration (p = 0.06 and p = 0.12). Vitamin D replacement does not seem to work via modifying the spinal inhibitory pathways that are involved in the formation of the cutaneous silent period. This is the first study to objectively investigate the effect of vitamin D replacement on central sensitization mechanisms.Publication Open Access Comparison of treatment outcomes in chronic coccygodynia patients treated with ganglion impar blockade versus caudal epidural steroid injection: a prospective randomized comparison study(KOREAN PAIN SOC, 2022-01-01) YOLCU, GÜNAY; Sencan, Savas; Yolcu, Gunay; Bilim, Serhad; Kenis-Coskun, Ozge; Gunduz, Osman HakanBackground: Coccygodynia is one of the chronic, refractory painful musculoskeletal disorders. Interventional procedures are applied to patients unresponsive to initial treatment in coccygodynia. This study aims to compare the treatment outcomes of ganglion impar block (GIB) and caudal epidural steroid injection (CESI) in patients with chronic coccygodynia. Methods: This study was a prospective randomized comparison study conducted between June 2019 and January 2021. Patients diagnosed with chronic coccygodynia were randomly divided into two groups: the GIB group and the CESI group. The severity of pain, presence of neuropathic pain, and quality of life were evaluated using the Numeric Rating Scale, Leeds Assessment of the Neuropathic Symptoms and Signs Scale, and Short Form-12 Health Survey (SF-12), respectively. Results: A total of 34 patients in each group were included in the final analyses. While there was a significant decrease in pain intensity in both groups in the 3-month follow-up, this decrease was more significant in the GIB group at the 3rd week. There was a significant improvement in the SF-12 physical score and the number of patients with neuropathic pain in both groups in the 3rd week, but this improvement was not observed in the 3rd month. Conclusions: Although GIB may provide more pain relief in short term, both GIB and CESI are useful treatment methods in coccygodynia unresponsive to more conservative treatments.Publication Open Access Assessment of the knowledge and awareness of a sample of young researcher physicians on reporting guidelines and the EQUATOR network: A single center cross-sectional study(MARMARA UNIV, FAC MEDICINE, 2020-01-31) YAĞCI, İLKER; Giray, Esra; Kenis Coskun, Ozge; Karacaatli, Meltem; Gunduz, Osman Hakan; Yagci, IlkerObjective: This study aimed to investigate knowledge and awareness of a sample of young researcher physicians about reporting guidelines and the EQUATOR network. Materials and Methods: One hundred young researcher physicians were enrolled for the study and evaluated using a questionnaire which assessed the level of usage and knowledge of reporting guidelines and the EQUATOR network. Results: Thirty-eight percent of the participants were aware of the EQUATOR network The most recognized reporting guidelines were CONSORT (32%), PRISMA (35%), and the least recognized ones were ARRIVE (12%) GRRAS (12%). The percentage of participants who were aware of the EQUATOR network and reporting guidelines were deficient. Seventy-three percent of the participants declared that they requested more information about reporting guidelines when they were asked whether they wished to be informed about reporting guidelines. There were statistically significant differences between specialists and residents regarding the level of knowledge on reporting guidelines and reporting guideline use except for PRISMA and SAMPL guidelines and their level of the desire to be informed about guidelines were similar. When participants whose publication number was above and below the mean of publications of all participants were compared, the level of reporting guidelines usage and knowledge of PRISMA, GRRAS were similar and both groups showed equal levels of desire to be informed about guidelines. Conclusion: The use and awareness of the EQUATOR network and reporting guidelines are low among young researcher physicians. To improve the quality of manuscript writing and the acceptance rates, knowledge and awareness of the EQUATOR network and reporting guidelines should be increased among young physicians doing research.Publication Metadata only A case report of lumbosacral plexopathy in a patient with a history of sacral chordoma and radiotherapy: Will the detection of myokymia on the EMG help to solve the case?(2023-01-01) ALBAYRAK, OSMAN; KENİŞ COŞKUN, ÖZGE; YAĞCI, İLKER; GÜNDÜZ, OSMAN HAKAN; Giray E., Albayrak O., KENİŞ COŞKUN Ö., YAĞCI İ., GÜNDÜZ O. H.BACKGROUND: When a patient with a prior history of malignancy and radiotherapy develops progressive weakness as a presentation of plexus involvement, the differential diagnosis usually rests between radiation-induced plexopathy and invasion from recurrent tumor. The presence of myokymic discharges is helpful in differentiating radiation-induced from neoplastic plexopathy.