Person: GÜNDÜZ, OSMAN HAKAN
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GÜNDÜZ
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OSMAN HAKAN
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Publication Metadata only The relationships of motor-evoked potentials to hand dexterity, motor function, and spasticity in chronic stroke patients: a transcranial magnetic stimulation study(SPRINGER HEIDELBERG, 2016) AKYÜZ, GÜLSEREN DERYA; Cakar, Engin; Akyuz, Gulseren; Durmus, Oguz; Bayman, Levent; Yagci, Ilker; Karadag-Saygi, Evrim; Gunduz, Osman HakanThe standardization of patient evaluation and monitoring methods has a special importance in evaluating the effectiveness of therapeutic methods using drugs or rehabilitative techniques in stroke rehabilitation. The aim of this study was to investigate the relationships between clinical instruments and transcranial magnetic stimulation (TMS)-evoked neurophysiological parameters in stroke patients. This study included 22 chronic post-stroke patients who were clinically assessed using the Motricity Index (MI), finger-tapping test (FTT), Motor Activity Log (MAL) 28, Brunnstrom motor staging and Ashworth Scale (ASH). Motor-evoked potential (MEP) latency and amplitude, resting motor threshold (rMT) and central motor conduction time (CMCT) were measured with TMS. Shorter MEP-latency, shorter CMCT, higher motor-evoked potential amplitude, and diminished rMT exhibited significant correlations with clinical measures evaluating motor stage, dexterity, and daily life functionality. rMT exhibited a negative correlation with hand and lower extremity Brunnstrom stages (r = -0.64, r = -0.51, respectively), MI score (r = -0.48), FTT score (r = -0.69), and also with amount of use scale and quality of movement scale of MAL 28 scores (r = -0.61, r = -0.62, respectively). Higher MEP amplitude and diminished rMT showed positive correlations with reduced ASH score (r = -0.65, r = 0.44, respectively). The TMS-evoked neurophysiologic parameters including MEP latency, amplitude, rMT and CMCT generally have positive correlation with clinical measures which evaluate motor stage, dexterity and daily life functionality. Additionally, spasticity has also remarkable relationships with MEP amplitude and rMT. These results suggest that TMS-evoked neurophysiological parameters were useful measures for monitoring post-stroke patients.Publication Metadata only Comparison of splinting and splinting plus low-level laser therapy in idiopathic carpal tunnel syndrome(SPRINGER LONDON LTD, 2009) YAĞCI, İLKER; Yagci, Ilker; Elmas, Ozlem; Akcan, Eylem; Ustun, Isil; Gunduz, Osman Hakan; Guven, ZeynepThis study aimed to compare the short-term efficacy of splinting (S) and splinting plus low-level laser therapy (SLLLT) in mild or moderate idiopathic carpal tunnel syndrome (CTS) with a prospective, randomized controlled study. The patients with unilateral, mild, or moderate idiopathic CTS who experienced symptoms over 3 months were included in the study. The SLLLT group received ten sessions of laser therapy and splinting while S group was given only splints. The patients were evaluated at the baseline and after 3 months of the treatment. Follow-up parameters were nerve conduction study (NCS), Boston Questionnaire (BQ), grip strength, and clinical response criteria. Forty-five patients with CTS completed the study. Twenty-four patients were in S and 21 patients were in SLLLT group. In the third-month control, SLLLT group had significant improvements on both clinical and NCS parameters (median motor nerve distal latency, median sensory nerve conduction velocities, BQ symptom severity scale, and BQ functional capacity scale) while S group had only symptomatic healing (BQ symptom severity scale). The grip strength of splinting group was decreased significantly. According to clinical response criteria, in SLLLT group, five (23.8%) patients had full and 12 (57.1%) had partial recovery; four (19%) patients had no change or worsened. In S group, one patient (4.2%) had full and 17 (70.8%) partial recovery; six (25%) patients had no change or worsened. Additionally, applied laser therapy provided better outcomes on NCS but not in clinical parameters in patients with CTS.Publication Open Access Assessment of the relationship between rectus femoris cross-sectional area and knee extension strength in the prosthesis users with transtibial amputation: A case-control study(2022-03-01) YAĞCI, İLKER; GÜNDÜZ, OSMAN HAKAN; Atalay K. G., Coskun O. K., Giray E., GÜNDÜZ O. H., YAĞCI İ.Objectives: This study aims to investigate cross-sectional area of the amputated-limb rectus femoris compared to the intact-limb and controls and to determine its correlation with functional strength and walking tests in prosthesis users with transtibial amputation. Patients and methods: Between October 2018 and April 2019, a total of 14 prosthesis users (12 males, 2 females; mean age: 47.1 +/- 16.2 years; range, 26 to 73 years) who met the inclusion criteria, and 14 age-, sex-, and dominancy-matched able-bodied controls (12 males, 2 females; mean age: 47.1 +/- 16.2 years; range, 26 to 73 years) were included in this case-control study. Cross-sectional area of rectus femoris (CSA-RF) was evaluated bilaterally by two independent examiners. Knee extension strength was measured bilaterally by using a handheld dynamometer. Functional strength and walking were assessed by Step-Up-Over and Walk-Across tests of the NeuroCom Balance Master (R) device. Results: The CSA-RF was found to be reduced in amputated-limb compared to the intact-limb and able-bodied controls (p<0.01). In the prosthesis users, the cross-sectional area difference between both limbs rectus femoris muscles was shown to be correlated with actual and functional knee extension strength, step length, and walking speed (p<0.05). Intra-and inter-observer reliability of CSA-RF on both sides were found to be good to excellent (intraclass correlation coefficient: 0.856-0.936). Conclusion: Ultrasonographic measurement of CSA-RF is a valid and reliable tool to assess the functional strength and walking in the prosthesis users with unilateral transtibial amputation.Publication Open Access Assessment of the knowledge and awareness of a sample of young researcher physicians on reporting guidelines and the EQUATOR network: A single center cross-sectional study(MARMARA UNIV, FAC MEDICINE, 2020-01-31) YAĞCI, İLKER; Giray, Esra; Kenis Coskun, Ozge; Karacaatli, Meltem; Gunduz, Osman Hakan; Yagci, IlkerObjective: This study aimed to investigate knowledge and awareness of a sample of young researcher physicians about reporting guidelines and the EQUATOR network. Materials and Methods: One hundred young researcher physicians were enrolled for the study and evaluated using a questionnaire which assessed the level of usage and knowledge of reporting guidelines and the EQUATOR network. Results: Thirty-eight percent of the participants were aware of the EQUATOR network The most recognized reporting guidelines were CONSORT (32%), PRISMA (35%), and the least recognized ones were ARRIVE (12%) GRRAS (12%). The percentage of participants who were aware of the EQUATOR network and reporting guidelines were deficient. Seventy-three percent of the participants declared that they requested more information about reporting guidelines when they were asked whether they wished to be informed about reporting guidelines. There were statistically significant differences between specialists and residents regarding the level of knowledge on reporting guidelines and reporting guideline use except for PRISMA and SAMPL guidelines and their level of the desire to be informed about guidelines were similar. When participants whose publication number was above and below the mean of publications of all participants were compared, the level of reporting guidelines usage and knowledge of PRISMA, GRRAS were similar and both groups showed equal levels of desire to be informed about guidelines. Conclusion: The use and awareness of the EQUATOR network and reporting guidelines are low among young researcher physicians. To improve the quality of manuscript writing and the acceptance rates, knowledge and awareness of the EQUATOR network and reporting guidelines should be increased among young physicians doing research.Publication Metadata only Comparative electrophysiological techniques in the diagnosis of carpal tunnel syndrome in patients with diabetic polyneuropathy(ELSEVIER IRELAND LTD, 2010) AKYÜZ, GÜLSEREN DERYA; Yagci, Ilker; Gunduz, Osman Hakan; Sancak, Seda; Agirman, Mehmet; Mesci, Erkan; Akyuz, GulserenObjective: To determine utility of comparative electrophysiological techniques in differentiating carpal tunnel syndrome (CTS) in the background of diabetic polyneuropathy (DPN). Design: Ninety diabetic patients were classified into three groups: normal, CTS, and DPN according to nerve conduction studies (NCSs). The patients in the DPN group were divided into two subgroups of DPN and DPN-CTS according to clinical criteria. The comparative electrophysiological parameters including median-radial sensory distal latency difference (M-RSLD), median-ulnar sensory distal latency difference (M-USLD) and lumbrical-interosseous median-ulnar distal latency difference (LIMULD) were compared in subgroups of DPN, DPN-CTS and CTS. Results: Thirty-five (38.8%), 47(52.3%), and 8(8.9%) patients were diagnosed as CTS, DPN, and normal, respectively, according to NCS. After clinical stratification, 25 patients were diagnosed as DPN and 22 patients were diagnosed as DPN-CTS. The mean M-USLD and LIMULD values were similar in CTS and DPN-CTS groups, but larger than DPN statistically (p < 0.05 for all). LIMULD, M-RSLD and M-USLD were positive in 88.4, 73 and 54% in the DPN-CTS group, respectively. Conclusions: Electrophysiological abnormalities were common in diabetic patients and LIMULD can identify CTS in diabetic DPN patients better than M-RSLD and M-USLD. (C) 2010 Elsevier Ireland Ltd. All rights reserved.Publication Metadata only A case report of lumbosacral plexopathy in a patient with a history of sacral chordoma and radiotherapy: Will the detection of myokymia on the EMG help to solve the case?(2023-01-01) ALBAYRAK, OSMAN; KENİŞ COŞKUN, ÖZGE; YAĞCI, İLKER; GÜNDÜZ, OSMAN HAKAN; Giray E., Albayrak O., KENİŞ COŞKUN Ö., YAĞCI İ., GÜNDÜZ O. H.BACKGROUND: When a patient with a prior history of malignancy and radiotherapy develops progressive weakness as a presentation of plexus involvement, the differential diagnosis usually rests between radiation-induced plexopathy and invasion from recurrent tumor. The presence of myokymic discharges is helpful in differentiating radiation-induced from neoplastic plexopathy.