Person: MİDİ, İPEK
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MİDİ
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İPEK
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Publication Metadata only Hemichorea associated with polycythaemia vera(SPRINGER, 2006) MİDİ, İPEK; Midi, I.; Dib, H.; Koseoglu, M.; Afsar, N.; Gunal, D. I.Chorea is a rare complication of polycythaemia vera. Polycythaemic chorea occurs predominantly in females and usually in generalised form. We present a 66-year-old woman with acute onset hemichorea-ballism with no vascular pathology in the basal ganglia region. A clear relationship was observed between the onset of chorea and worsening of haematological parameters in the patient. After repeated phlebotomies the patient's clinical status was improved. Polycythaemic chorea must be considered, especially in the elderly, as early diagnosis leads to effective treatment and prevention of complications.Publication Metadata only Intractable seizure with hypoglycemia: A mysterious retroperitoneal fibrosarcoma(2022-01-01) MİDİ, İPEK; EKİNCİ, GAZANFER; MİDİ İ., Okay B. B. , Cetin S. Z. , EKİNCİ G.Publication Metadata only Clinical and Radiological Features in CADASIL and NOTCH3-Negative Patients: A Multicenter Study from Turkey(KARGER, 2014) MİDİ, İPEK; Ince, Birsen; Benbir, Gulcin; Siva, Aksel; Saip, Sabahattin; Utku, Ufuk; Celik, Yahya; Necioglu-Orken, Dilek; Ozturk, Serefnur; Afsar, Nazire; Aktan, Sevinc; Asil, Talip; Bakac, Goksel; Ekmekci, Hakan; Gokce, Mustafa; Krespi, Yakup; Midi, Lpek; Varlibas, Figen; Citci-Yalcinkaya, Beyza; Goksan, Baki; Uluduz, Derya; Uyguner, OyaBackground: The diversity of clinical presentation and neuroimaging findings of CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) from different regions of the world has not yet been studied in depth. Here we investigated the variability of clinical, radiological and genetic data of 48 patients analyzed for NOTCH3 mutation in Turkey. Methods: Clinical evaluation was made according to a preformed questionnaire. Cranial neuroimaging findings were determined on the basis of T1, T2, FLAIR and proton-density magnetic resonance scans. For genetic analysis, polymerase chain reaction was performed with primers flanking exons 2-6 and 11 of NOTCH3 gene. Results:Twenty-five patients (52.1%) were diagnosed as CADASIL with NOTCH3 mutation, while 23 patients (47.9%) had no mutation (NOTCH3-negative patients). The mean age and age at stroke onset were lower in male CADASIL patients (p < 0.03). A family history of migraine (p = 0.012), stroke (p < 0.001), recurrent strokes (p = 0.020) and dementia (p = 0.012) was more common in CADASIL patients. Temporal pole involvement was more common in CADASIL patients (p = 0.004). Conclusion: It is of clinical importance to identify the heterogeneity of CADASIL from different countries due to a low correlation of clinical and radiological data with respect to NOTCH3 mutation. (C) 2014 S. Karger AG, BaselPublication Metadata only Theory of mind and its relationship with alexithymia and quality of life in patients with psychogenic nonepileptic seizures: Comparisons with generalised epilepsy and healthy controls(W B SAUNDERS CO LTD, 2021) MİDİ, İPEK; Gursoy, Suha Can; Ergun, Serhat; Midi, Ipek; Topcuoglu, VolkanObjective: Psychogenic nonepileptic seizures (PNES) are associated with high alexithymia, social cognition problems and low quality of life (QoL). Theory of Mind (ToM) has been studied in several conditions as a significant predictor of QoL. We aimed to assess the relationship between ToM abilities, alexithymia and subjective QoL in PNES patients and compare with generalised epilepsy (ES) patients and healthy controls. Method: Patients with PNES (n = 28), ES (n = 28) and healthy volunteers (n = 28) were evaluated for alexithymia and quality of life (QoL) with Toronto Alexithymia Scale-20 (TAS-20) and Short Form-36 (SF-36). Reading the Mind in the Eyes test was used for assessment of affective ToM and Hinting Task and Strange Stories tests for cognitive ToM abilities. Results: Analyses revealed lower SF-36 scores and poorer ToM performance in the PNES group compared to healthy group and poorer cognitive ToM performance than ES group. Cognitive ToM performance was inversely correlated with TAS-20 difficulty identifying feelings subscale and physical functioning subscale of SF-36 in the PNES group. Conclusion: These results are consistent with previous research on PNES and other somatoform disorders and suggest that PNES is associated with impaired ToM task performance. ToM task performance might be related to specific aspects of alexithymia and QoL.Publication Metadata only Motor imagery EEG signal classification using image processing technique over GoogLeNet deep learning algorithm for controlling the robot manipulator(ELSEVIER SCI LTD, 2022) AK, AYÇA; Ak, Ayca; Topuz, Vedat; Midi, IpekControlling of a robotic arm using a brain-computer interface (BCI) is one of the most impressive applications. In this study, a novel method for the classification of motor imaging (MI) electroencephalography (EEG) signals are proposed for BCI. EEG signals are divided into three secondary tables, which were converted into spectrogram images. After applying the spectrogram method, the obtained images are divided into folder structures and deep learning is performed. In the deep learning stage, 400 images are obtained for each task as input to the Goo-gLeNet. After the deep learning completed, the presented system has been tested to imagine up, down, left and right movement to control the movement of the robot arm. It is observed that the robot arm performs the desired movement over 90% accuracy.Publication Metadata only Does measurement of the jugular foramen diameter on MRI help to differentiate transverse sinus thrombosis from unilateral transverse sinus hypoplasia?(SPRINGER-VERLAG ITALIA SRL, 2021) MİDİ, İPEK; Gul, Burcu; Samanci, Cesur; Uluduz, Derya Ugurlu; Alis, Deniz; Midi, Ipek; Kocer, Naci; Islak, Civan; Kizilkilic, OsmanBackground and Purpose The transverse sinus (TS) is a frequent location of cerebral venous thrombosis. However, unilateral TS hypoplasia is a frequent variation and radiological imaging pitfall in the diagnosis because it may mimic unilateral TS thrombosis. The purpose of this study is to find a cutoff value for bilateral jugular foramen (JF) diameter ratios on magnetic resonance imaging (MRI) for differentiating TS thrombosis from TS hypoplasia. Materials and Methods We retrospectively reviewed magnetic resonance venography results for 174 patients with reduced unilateral TS caliber resulting from either unilateral thrombosis (80 patients) or unilateral hypoplasia (94 patients). We calculated the ratio by proportioning the diameter of the JF ipsilateral to the TS with caliber reduction to the diameter of the contralateral JF. The Mann-WhitneyUtest was used to compare the ratios between thrombosis and hypoplasia groups, and the cutoff value was calculated by receiver-operating characteristic curve analysis. Results The ratio of bilateral JF diameters was lower in patients with hypoplasia than those with thrombosis (P < .01). The cutoff value to determine the diagnosis of TS hypoplasia with maximum accuracy was 0.638, with a sensitivity of 91.3% and specificity of 64.9%. Conclusion In equivocal cases, calculating the cutoff value by proportioning the diameter of JF ipsilateral to the TS with caliber reduction to the contralateral JF seems to be an efficient, quick, and straightforward method and valuable aid to differentiate TS thrombosis from TS hypoplasia.Publication Metadata only Visual field analysis in patients with Parkinson's disease(ELSEVIER SCI LTD, 2008) MİDİ, İPEK; Yenice, Ozlem; Onal, Sumru; Midi, Ipek; Ozcan, Eda; Temel, Ahmet; I-Gunal, DilekBackground: To evaluate visual field changes in patients with Parkinson's disease. Methods: Standard automated perimetry of 14 patients (28 eyes) with Parkinson's disease (PD) were compared with controls. PD patients with Unified Parkinson's Disease Rating Scale (UPDRS) score below 25 were included in the study. Results: Visual field indices including mean deviation (-4.69 +/- 2.72 vs. -1.71 +/- 1.30, p = 0.0008), pattern standard deviation (3.94 +/- 1.94 vs. 2.30 +/- 0.41, p = 0.001), and corrected pattern standard deviation (3.23 +/- 2.18 vs. 1.20 +/- 0.91, p = 0.003), were significantly worse in patients with PD when compared with the control group. Bilateral glaucoma-like visual field defects were evident in six patients. Conclusion: Parkinson's patients had worse visual field indices suggesting a common insult in the etiopathogenesis of nerve fiber layer damages observed in glaucoma and PD. (c) 2007 Elsevier Ltd. All rights reserved.Publication Metadata only Bilir kişi raporu(2020-09-01) MİDİ, İPEK; AKVARDAR, YILDIZ; İNANICI, MEHMET AKİF; İŞAK, BARIŞ; MİDİ İ., AKVARDAR Y., TOPÇUOĞLU V., İNANICI M. A., İŞAK B.Publication Metadata only Headache characteristics and frequency of migraine in patients with cervical artery dissections(SPRINGER HEIDELBERG, 2021) MİDİ, İPEK; Uluduz, Derya; Mastanzade, Toghrul; Demirci, Seden; Midi, Ipek; Goksan, BakiHeadache is a common symptom of cervical artery dissections (CAD). Sometimes, it can be the only symptom and mimic migraine. We aimed to investigate headache characteristics and previous history of migraine in CAD patients, and to compare headache features between patients with internal carotid artery dissection (ICAD) and vertebral artery dissection (VAD). We investigated 53 CAD patients (n = 28 with ICAD, n = 25 with VAD). Demographic and clinical data were evaluated retrospectively. Headache information was obtained from the patient interviews with a structured questionnaire (based on the International Headache Society criteria). The patients with headache were assessed by headache specialist with a face-to-face interview. Headache was evaluated according to International Classification Committee of the International Headache Society ICHD. Headache (n = 38, 71.7%) was the most common symptom in CAD patients, which was mostly thunderclap, throbbing, intense and ipsilateral to dissection. Headache frequency and neck pain were significantly higher in VAD patients (p = 0.002, p < 0.001, respectively). Photophobia and phonophobia were also more common in patients with VAD (p < 0.001, p < 0.001, respectively). 29 (54.7%) of CAD patients had a prior history of headache, that 20 (37.7%) of them met the migraine criteria. CAD should be considered in patients with severe unilateral throbbing headache with phonophobia and photophobia, even in patients with a history of migraine. Phonophobia and photophobia may be more common symptoms in VAD patients. Because headache commonly precedes the development of cerebral ischemic events, it needs prompt and accurate diagnosis and treatment.Publication Metadata only A Multicenter Study of 1144 Patients with Cerebral Venous Thrombosis: The VENOST Study(ELSEVIER, 2017) MİDİ, İPEK; Duman, Taskin; Uluduz, Derya; Midi, Ipek; Bektas, Hesna; Kablan, Yuksel; Goksel, Basak K.; Milanlioglu, Aysel; Orken, Dilek Necioglu; Aluclu, Ufuk; Colakoglu, Sena; Tufekci, Ahmet; Bakar, Mustafa; Nazliel, Bijen; Tascilar, Nida; Goksan, Baki; Kozak, Hasan Huseyin; Demir, Serkan; Misirli, Cemile Handan; Kucukoglu, Hayriye; Cinar, Nilgun; Domac, Fusun Mayda; Ozturk, Serefnur; Yayla, Vildan; Karahan, Ali Yavuz; Afsar, Nazire; Goksu, Eylem Ozaydin; Mengulluoglu, Necdet; Aytac, Emrah; Yesilot, Nilufer; Ince, Birsen; Yalin, Ozgur Osman; Oruc, Serdar; Demirci, Seden; Senol, Mehmet Guney; Yilmaz, Arda; Gokce, Mustafa; Kuspeci, Ozge Yilmaz; Uzuner, Gulnur; Caglayan, Hale Zeynep Batur; Acikgoz, Mustafa; Zeydan, Burcu; Ozdag, Fatih; Baybas, Sevim; Ekmekci, Hakan; Cabalar, Murat; Yaman, Mehmet; Yurekli, Vedat Ali; Tekeli, Hakan; Genc, Hamit; Utku, Uygar; Tokuc, Firdevs Ezgi Ucan; Uzuner, NevzatBackground: Based on a number of small observational studies, cerebral venous sinus thrombosis has diverse clinical and imaging features, risk factors, and variable outcome. In a large, multicenter cerebral venous thrombosis (VENOST) study, we sought to more precisely characterize the clinical characteristics of Caucasian patients. Methods: All data for the VENOST study were collected between the years 2000 and 2015 from the clinical follow-up files. Clinical and radiological characteristics, risk factors, and outcomes were compared in terms of age and sex distribution. Results: Among 1144 patients 68% were women, and in older age group (>50 years) male patients were more prevalent (16.6% versus 27.8%). The most frequent symptoms were headache (89.4%) and visual field defects (28.9%) in men, and headache (86.1%) and epileptic seizures (26.8%) in women. Gynecological factors comprised the largest group in women, in particular puerperium (18.3%). Prothrombotic conditions (26.4%), mainly methylenetetrahydrofolate reductase mutation (6.3%) and Factor V Leiden mutation (5.1%), were the most common etiologies in both genders. 8.1% of patients had infection-associated and 5.2% had malignancy-related etiology that was significantly higher in men and older age group. Parenchymal involvement constitutively hemorrhagic infarcts, malignancy, and older age was associated with higher Rankin score. Epileptic seizures had no effect on prognosis. Conclusions: Clinical and radiological findings were consistent with previous larger studies but predisposing factors were different with a higher incidence of puerperium. Oral contraceptive use was not a prevalent risk factor in our cohort. Malignancy, older age, and hemorrhagic infarcts had worse outcome. (c) 2017 National Stroke Association. Published by Elsevier Inc. All rights reserved.