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ÖZDOĞMUŞ, NECMETTİN ÖMER

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ÖZDOĞMUŞ

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NECMETTİN ÖMER

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2008 - 20102
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Subject: DISEASE ×

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    The high 2D:4D finger length ratio effects on atherosclerotic plaque development
    (ELSEVIER IRELAND LTD, 2010) ÖZDOĞMUŞ, NECMETTİN ÖMER; Ozdogmus, Omer; Cakmak, Yusuf Oezguer; Coskun, Murat; Verimli, Ural; Cavdar, Safiye; Uzun, Ibrahim
    Background: The index finger to ring finger length ratio (2D:4D) of the right hand are affected by prenatal testosterone levels in male. To date, it has been determined that the high 2D: 4D ratio is related to the myocardial infarction, however no research has revealed the relationship between the high 2D: 4D ratio whose coronary artery shows atherosclerotic plaque development. Objective: The aim of this study was to display the relationship between the 2D: 4D ratio and atherosclerosis formation in male autopsy cases. Methods: We designed a study in 100 heterosexual male autopsies whose mean age was 21.4 +/- 2.47 (range between 17 and 25). The 2nd and 4th digits were measured on the palmar surface of the right hand and taken the right coronary artery to show the atherosclerotic plaque development. Results and conclusion: Grade 3 group had significantly higher 2D: 4D ratio compared to Grade 1 and Grade 2 groups (p = 0.02 for both). (C) 2009 Elsevier Ireland Ltd. All rights reserved.
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    Changing diameters of cerebral vessels with age in human autopsy specimens: Possible relationships to atherosclerotic changes
    (GEORG THIEME VERLAG KG, 2008) ÖZDOĞMUŞ, NECMETTİN ÖMER; Ozdogmus, O.; Cakmak, O.; Yalin, A.; Keklik, D.; Uzun, Y.; Cavdar, S.
    Aims/Objectives: It has been previously recognized that the anatomy of arterial bifurcations influences blood flow and has a significant role in the development of vascular disease. Material and Methods: In the present study, we measured the average diameters of the infernal carotid (ICA), anterior cerebral (ACA), and middle cerebral arteries (MCA) in autopsy cases. We also calculated the outflow to inflow area ratios for four distinct age groups and for each gender, using 33 adult autopsies and 7 fetuses. Results: The area ratios decreased with age in both male and female samples. The decrease in the male (30 %, p < 0.05) was greater than the decrease for the female (17 %, p > 0.05). The average diameter of the ACA, MCA and ICA of both female and male cases increased up to the 25-44 age group, decreased for the 45-64 age group, with a second increase above the age of 65. Conclusions: The decrease in the area ratios and the pattern of changes of the dimensions of the cerebral vessels with age are useful to examine the causal relationships of these pathologic conditions and raises novel questions about age and gender differences in the structure of the intracranial vessels.