Person: YOLDEMİR, AHMET TEVFİK
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YOLDEMİR
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AHMET TEVFİK
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Publication Metadata only Does the duration of gonadotropin stimulation affect embryo quality on post-retrieval day 3?(INFORMA HEALTHCARE, 2011) YOLDEMİR, AHMET TEVFİK; Yoldemir, TevfikAim. To determine if the duration of ovarian hyperstimulation affects quality of embryos on the 3rd day. Methods. Retrospective cohort study was designed in a University affliated hospital. Six-hundred fifteen women undergoing first IVF treatment were grouped according to the duration of controlled ovarian hyperstimulation (COH) in long-down regulated cycles. Group A consisted of women with 8 or less days of COH, Group B consisted of women who had between 9 and 10 days of COH and Group C had 11days or more COH. The degree of fragmentation and asymmetry of blastomeres were compared for the 3rd day after oocyte retrieval. Results. On day 3, there were more embryos with 10-25% fragmentation in Group A than in Group B. Embryos were also less symmetrical in Group A than in Group B. Conclusions. COH cycles which are shorter than 9 days result in more embryos with more than 10% fragmentation on post-retrieval day 3.Publication Metadata only Does the timing of mock embryo transfer trial improve implantation in intracytoplasmic sperm injection cycles?(TAYLOR & FRANCIS LTD, 2011) YOLDEMİR, AHMET TEVFİK; Yoldemir, Tevfik; Erenus, MithatAim. To determine if endometrial trauma during embryo transfer trials (ETTs) improves implantation and clinical pregnancy rates in intracytoplasmic sperm injection treatment cycles. Patients. One-hundred fifty women undergoing their first IVF treatment were included in a prospective randomised study in a University hospital clinic. ETTs were performed either on day 21 of the previous cycle, or on day 6 of the controlled ovarian hyperstimulatin (COH) cycle, or conducted at least two cycles before COH cycle. Clinical pregnancy and implantation rates were compared between the groups. Results. There was no difference between the groups in terms of clinical pregnancy or implantation rates. Conclusion. Endometrial trauma by ETTs performed either during the preceeding cycle or on day 6 of the COH cycle does not improve pregnancy rates.Publication Metadata only Fertility in midlife women(TAYLOR & FRANCIS LTD, 2016) YOLDEMİR, AHMET TEVFİK; Yoldemir, T.Reduced maternal fertility is the consequence of depletion of follicles with maternal aging. In a 35-year-old woman, approximately 9.1% of the residual follicle pool disappears annually without entering into the growing stage, whereas, in a 45-year-old woman, this number triples. After the age of 35 years, the frequency of aneuploidies in oocytes increases sharply. Roughly 50-70% of mature oocytes from a 40-year-old woman have chromosomal abnormalities. The clinical pregnancy and implantation rates are lower in midlife women. Various controlled ovarian stimulation interventions have been suggested for the management of women in advanced age, most of whom are likely to be poor-responder patients. Currently, systematic reviews and meta-analyses suggest that there is insufficient evidence to recommend most of the treatments proposed to improve pregnancy rates in these poor responders. Minimal stimulation or natural cycle in vitro fertilization may be offered, without compromising the already existing pregnancy results.Publication Metadata only Follicular dominance on the fifth day of controlled ovarian stimulation reduces implantation in long down-regulated ICSI cycles(ELSEVIER SCIENCE BV, 2011) YOLDEMİR, AHMET TEVFİK; Yoldemir, Tevfik; Erenus, Mithat; Durmusoglu, FatihObjective: To determine if follicular dominance on the fifth day of controlled ovarian stimulation (COS) predicts implantation rates in down-regulated intracytoplasmic sperm injection (ICSI) cycles. Study design: One hundred and sixty-two consecutive women undergoing ICSI treatment with long down-regulation and recombinant follicle-stimulating hormone injections were included in a prospective cohort analysis. The clinical pregnancy and implantation rates per transfer were compared between two groups, one with and the other without follicular dominance detected by ultrasound on the fifth day of COS. Results: There was no significant difference between the groups regarding the number of good quality embryos transferred, but clinical pregnancy and implantation rate per transfer were higher in group with follicular synchrony. Conclusions: Follicular dominance on COS day 5 results in reduced implantation rates after ICSI. (C) 2011 Elsevier Ireland Ltd. All rights reserved.Publication Metadata only The effect of retrieved oocyte count on pregnancy outcomes in an assisted reproduction program(SPRINGER HEIDELBERG, 2010) YOLDEMİR, AHMET TEVFİK; Yoldemir, Tevfik; Fraser, Ian S.To determine if women with less than five eggs retrieved do as well as women with more eggs retrieved in terms of pregnancy outcomes in our assisted reproduction program. Two hundred one women undergoing in vitro fertilization treatment at Fertility Unit in Royal Prince Alfred Hospital, University of Sydney, Australia were selected for retrospective evaluation. The women were grouped according to the number of oocytes retrieved at ovum pick-up. Group A consisted of women with less than 5 oocytes, group B with 5 to 10 oocytes and group C with 11 to 15 oocytes collected. Clinical and ongoing pregnancy rates were compared. There was no difference between the groups in terms of clinical and ongoing pregnancy rates. With good IVF lab conditions, if a patient reaches embryo transfer, the number of eggs retrieved should not affect the likelihood of pregnancy outcome in an assisted reproductive technology treatment.