Person: KESİM, SELİN
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KESİM
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SELİN
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Publication Open Access Lhermitte-duclos disease related with cowden syndrome mimicking metastatic lung cancer on FDG PET/CT(2023-02-01) KESİM, SELİN; KESİM S., Ozguven S., Oksuzoglu K., Erdil T. Y.Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.ABSTRACT: Cowden syndrome is characterized by multiple hamartomatous and neoplastic lesions including Lhermitte-Duclos disease, which is the main criterion for the diagnosis. Herein, we presented a patient with suspected metastatic disease referred to PET/CT, which showed mildly hypermetabolic multinodular thyroid goiter, multiple hamartomatous pulmonary, and breast nodules. Also, intense hypermetabolism was noted on the cerebellar tumor lesion. Lhermitte-Duclos disease was diagnosed based on the characteristic MRI findings, and she was followed up with a diagnosis of Cowden syndrome. Our case indicates that Cowden syndrome should be included as a differential diagnosis of abnormal FDG uptake in the multiple systemic hamartomatous tumors.Publication Open Access Ga-68-Tetraazacyclododecane Tetraacetic Acid-DPhe1-Tyr3-Octreotate Positron Emission Tomography/Computed Tomographic Findings of Large-Cell Neuroendocrine Carcinoma of the Lung in a Child(2022-10-01) FİLİZOĞLU, NUH; KESİM, SELİN; ÖZGÜVEN, SALİH; Filizoglu N., Kesim S., ÖZGÜVEN S.Primary lung cancers in children are rare, and most children are diagnosed incidentally while being investigated for another medical problem. The diagnosis of primary lung tumors in children is very difficult because many children are asymptomatic until the advanced stages of the disease and nonspecific imaging findings. Although the usage of 68Ga-tetraazacyclododecane tetraacetic acid-DPhe1-Tyr3-octreotate (68Ga-DOTATATE) positron emission tomography/computed tomography (PET/CT) in adult patients is well known, it is a relatively new imaging modality for the pediatric patient group. Herein, we presented a unique case of large-cell neuroendocrine carcinoma of the lung in a child on 68Ga-DOTATATE PET/CT.Publication Open Access 18 F-FDG PET/CT imaging of a Grade 3 lymphomatoid granulomatosis in an immunocompromised pediatric patient(2023-02-01) KESİM, SELİN; ÖZGÜVEN, SALİH; ÖNEŞ, TUNÇ; KESİM S., Şen F., ÖZGÜVEN S., ÖNEŞ T.Lymphomatoid granulomatosis is a rare extranodal Epstein-Barr virus-driven B-cell lymphoproliferative disease, involving predominantly lung, less often skin, kidney, and central nervous system. Here, we present a pediatric case with primary immunodeficiency, diagnosed with pathologically proven pulmonary grade-III lymphomatoid granulomatosis.18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) imaging demonstrated18F-FDG avid pulmonary masses with central air-bronchograms and cavitations. Although the definitive diagnosis depends on biopsy,18F-FDG PET/CT serves as a complementary imaging tool to evaluate the extent of the disease and response to treatment.Publication Open Access Şiddetli kaudal regresyon sendromu olan pediatrik bir hastada tek foton emisyonlu bilgisayarlı tomografi/bilgisayarlı tomografi ile hibrid renal kortikal görüntüleme(2022-02-01) KESİM, SELİN; TUROĞLU, HALİL TURGUT; ÖZGÜVEN, SALİH; ERDİL, TANJU YUSUF; ÖNEŞ, TUNÇ; KESİM S., TUROĞLU H. T., ÖZGÜVEN S., ÖNEŞ T., ERDİL T. Y.© 2022 by Turkish Society of Nuclear Medicine Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi.Caudal regression syndrome (CRS) or sacral agenesis is a rarely seen malformation with a varying degree of structural abnormalities, including multiorgan system dysfunctions, reported with higher incidence among children of mothers with diabetes, as in this case. Spinal anomalies can range from coccyx hemiagenesis to the total absence of lower lumbar vertebrae and sacrum in most severe cases. Herein, we have presented a 9-year-old patient with CRS who had renal failure. Technetium-99m dimercaptosuccinic acid renal scintigraphy revealed bilaterally non-functioning kidneys with no renal cortical uptake. Renal anomalies in CRS with vertebral, anorectal, cardiac, trachea-esophageal, renal, and limb anomalies association include one-sided renal agenesis, multicystic dysplastic kidneys, and ureter duplications.