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TOPUZOĞLU, AHMET

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TOPUZOĞLU

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AHMET

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  • PublicationOpen Access
    Assessment of adjustment disorder in people with COVID-19 infection
    (2023-01-01) PEKER, MEHMET SERTAÇ; TOPUZOĞLU, AHMET; PEKER M. S., TOPUZOĞLU A.
    Objective: This study aimed to evaluate the development of adjustment disorder according to the ADNM-20 (Adjustment Disorder New Module-20) scale in participants who were followed up for Covid-19 infection. Methods: A cross-sectional survey was conducted from September to November 2020. After sample size calculation, we aimed to reach minimum 170 people out of 1290 people who applied to the hospital for Covid-19 disease treatment. Participants were selected from the patients admitted to the hospital using a simple stratified random sampling method. We reached 182 people after treating the patients who were followed up with Covid-19 infection in a University Hospital in Istanbul, Turkey. A questionnaire and the Adjustment Disorder New Module-20 scale were applied via phone / mail at the end of the 6th month after Covid-19 related hospital admission by researchers. Results: Adjustment disorder was found in 28.8 % (n=42) of the participants disorder according to the ADNM-20 scale. While the rate of development of adjustment disorder due to Covid-19-related stress was 26.7 % (n=39); the rate of development of adjustment disorder due to non-Covid-19 stress was found to be 2.1 % (n=3). With the increase in stress load, the development of adjustment disorder increased significantly. The frequency of developing Covid-19-related stress-related adjustment disorder was statistically significantly increased with the duration of exposure to stress. Conclusion: We have found out that one out of every four people who apply to the hospital for healthcare services due to Covid-19 infection may develop an adjustment disorder. Assessment of the adjustment disorder more frequently and making early interventions may contribute to the prevention of progressive mental disorders.
  • PublicationOpen Access
    A qualitative analysis evaluating how medical students perceive COVID-19 pandemic and its impact on their lives: Life in the Pandemic
    (2023-06-01) AYVAZ, İLKNUR; GİRGİN, ŞEVKET; LÜLECİ, NİMET EMEL; HIDIROĞLU, SEYHAN; TOPUZOĞLU, AHMET; SAVE, DİLŞAD; KARAVUŞ, MELDA; Ataoğlu B. N., Kesen Yurtcanlı C. H., Doğanç F. B., Çekici D., Peker Ş., Bakır Keser N., Ayvaz İ., Girgin Ş., Sandal Kılıç A., Doğan Jamil S., et al.
    One of the groups experiencing the pandemic’s effects were students. This study was aimed to evaluate the effects of the COVID-19 pandemic on the lives of medical students and also to see their perspectives about the pandemic. This study is designed as a qualitative study. In-depth interviews were conducted with 30 medical students on an online platform in February 2022, at the end of the third peak period. A semi-structured question guide used as a data collection tool. First, questions about individual characteristics then open-ended questions about their COVID-19 pandemic perception and its impact on their lives were asked. The thematic analysis method was used and \"Life in the pandemic\" were grouped into two main themes: 1.Perception of the Pandemic and Consequent Impact on Life and 2. Pandemic Period and Its Impact on Life. The median age was 22. Half of the participants have been diagnosed with COVID-19. All of the participants were vaccinated. In this study it has been observed that the majority of the medical students have perceived the COVID-19 pandemic as a difficult period and also as a new, uncertain and adverse situation. Another adverse effect perceived by the majority was restriction of social life. Fear and anxiety were most commonly used to express their mood during the pandemic. During the pandemic students individual, mental and social lives are highly affected. While negative effects are generally seen during the social isolation process, this situation has eased with the normalisation of the process.
  • PublicationOpen Access
    Asemptomatik covıd-19 olgularında bulaştırıcılığın ve ilişkili faktörlerin değerlendirilmesi
    (2022-01-01) GİRGİN, ŞEVKET; TOPUZOĞLU, AHMET; SAVE, DİLŞAD; Peker Ş., Kurnaz Ay M., Girgin Ş., Topuzoğlu A., Save D.
    COVID-19 (SARS-CoV-2) pandemisi; prevalansı, ciddi klinik sonuçları ve kolay bulaşan bir enfeksiyon olması nedeniyle günümüzün en öncelikli halk sağlığı sorunları arasında bulunmaktadır. Enfeksiyonun kliniği asemptomatik düzeyden çoklu organ yetmezliğine değişiklik göstermektedir. Araştırmalara göre COVID-19 enfeksiyonu geçirenlerin %17,9-%80,0’inin asemptomatik olgular olduğu bildirilmiştir. Asemptomatik olguların önlem alınmaması halinde COVID-19’u geniş kitlelere bulaştırma potansiyeli üzerine tartışmalar sürmektedir. Ayrıca asemptomatik olgularda hastaların viral yükü, viral bulaşma modelleri ve potansiyel enfektivitesi ile ilgili belirsizlikler mevcuttur. Serolojik testlerle hastalığın immün sistem üzerindeki etkileri izlenebilmektedir fakat enfeksiyonu geçiren bireylerde bağışıklık süresine ilişkin net bir uzlaşma sağlanamamıştır. Bu belirsizliklerin açığa kavuşturulması salgınla mücadele açısından önemli bir yere sahiptir.Bu makalede; COVID-19 enfeksiyonunu asemptomatik olarak geçiren olgularla ilgili yapılmış olan araştırmalarderlenerek olguların tespiti, hastalığı bulaştırma düzeyleri, viral yükleri, bulaştırıcılık süreleri ve potansiyel enfektiviteleriile ilgili konular tartışılmıştır.
  • PublicationOpen Access
    Corpus callosum volume in patients with first-episode psychosis
    (2022-06-01) TOPUZOĞLU, AHMET; Agdanlil O., TOPUZOĞLU A., KARABAY N., Alptekin K.
    Objective In first-episode psychosis, a relationship may exist between disruption communication between two brain hemispheres and psychosis symptomatology. We aimed to investigate the relationship between corpus callosum (CC) volume and psychosis symptomatology in patients with first-episode psychosis. Methods This is a retrospective case-control study wherein first-episode psychosis cases and healthy controls were included from inpatient unit archives of the Department of Psychiatry and Department of Radiology, Dokuz Eylül University School of Medicine. Psychosis symptoms were assessed using the positive and negative syndrome scale (PANSS). The CC, the chief connection between two brain hemispheres, was examined using magnetic resonance imaging (MRI); 27 patients with first-episode psychosis and 29 healthy volunteers were evaluated via 1.5-T MR. MRI findings of CC volumes of the two groups were compared. Correlations between PANSS scores and CC volume were also evaluated. Results The CC volume was lower in patients with first-episode psychosis than in healthy controls. Moreover, we observed a significant negative correlation between the CC volume and emotional withdrawal scores, and a significant positive correlation between the CC volume and hallucinations. Conclusions The CC is a vital structure that connects two frontal lobes of the brain. There may be CC abnormalities in first-episode psychosis. Emotional withdrawal is associated with decreased CC volume, whereas hallucinations are associated with increased CC volume. The development of these symptoms may be associated with changes in CC connections.