Person: SAKALLI KANİ, AYŞE
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SAKALLI KANİ
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AYŞE
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Publication Open Access Evaluation of depression, anxiety, alexithymia, attachment, social support and somatization in functional dyspepsia(TAYLOR & FRANCIS LTD, 2019-01-02) SAKALLI KANİ, AYŞE; Kani, Haluk Tarik; Dural, Uzay; Kani, Ayse Sakalli; Yanartas, Omer; Kiziltas, Safak; Enc, Feruze Yilmaz; Atug, Ozlen; Deyneli, Oguzhan; Kuscu, Kemal; Imeryuz, NeseAIM: The psychiatric and psychosocial aetiology of Functional dyspepsia is not well known. In the present study, our aim is to determine the relative contributions of psychiatric predictors - i.e. depression, anxiety, somatization, alexithymia - in relation with socio-psychological factors, specifically their personal characteristics (i.e. emotional attachment) and perceived social support, in distinguishing FD from organic dyspepsia and healthy samples. MATERIAL AND METHODS: An estimated 30 functional dyspepsia, 29 organic dyspepsia patients who were admitted to our gastroenterology outpatient clinic and 27 healthy controls were enrolled to our study. Beck Depression Inventory, Toronto Alexithymia Scale, Adult Attachment Scale, State-Trait Anxiety Inventory, Multidimensional Scale of Perceived Social Support and somatization sub-scale of Symptom Checklist-90 were provided to all patients and healthy controls. All participants were examined by a gastroenterologist and a psychiatrist. RESULTS: Healthy controls were younger than organic dyspepsia group and women/men rate was lower in organic dyspepsia than other two groups. Depression score was higher in functional dyspepsia group than in healthy controls and functional dyspepsia group's attachment syle was more secure than that of the healthy control group. Somatization rate was seen higher in functional dyspepsia group with psychiatric examination. There was no significant difference seen in anxiety, alexithymia and social support between the three groups. DISCUSSION: Anxious-avoidant attachment profile as well as the higher propensity to have depressive and anxiety symptoms might be critical psychiatric and psychosocial factors underlying FD's aetiology. A multidisciplinary approach is needed in the follow up of functional dyspepsia patients. Psychological evaluation and treatment would increase the life quality of dyspepsia patients.Publication Metadata only The Effect of Dream Anxiety on Sleep Quality in Inflammatory Bowel Diseases(KARGER, 2020) SAKALLI KANİ, AYŞE; Kani, Haluk Tarik; Kani, Ayse Sakalli; Dural, Uzay; Basgoze, Emre; Aksu, Cagri; Kahraman, Merve Meric; Alahdab, Yesim Ozen; Atug, Ozlen; Kuscu, Kemal; Imeryuz, NeseIntroduction:Declining sleep quality is a well-known issue in inflammatory bowel disease (IBD), but dream characteristics of patients with IBD and their role in sleep quality are unknown. In this study, we aimed to examine whether and how patients with ulcerative colitis (UC) and Crohn's disease (CD) differ on sleep quality, sleepiness level, and dream anxiety (DA) level compared to healthy controls (HC), controlling for their depressive and anxious tendencies.Methods:Patients and HCs were enrolled prospectively into the study. The Van DA Scale, Pittsburg Sleep Quality Index, Epworth Sleepiness Scale, Beck Depression Index, and State-Trait Anxiety Inventories were used to assess DA, sleep quality, sleepiness, depression, and anxiety, respectively.Results:Patients with IBD had significantly lower depression (p= 0.004), state anxiety (p= 0.0001), trait anxiety (p= 0.004), and DA (p= 0.0001) than HCs. Although no statistically significant difference in sleep quality was found (p= 0.99), daytime sleepiness was more common in HCs than in IBD patients (p = 0.0001). No statistically significant difference was seen in depression, state anxiety, trait anxiety, DA, sleep quality, and daytime sleepiness between patients with CD and those with UC. No correlation was found between disease activity indices and psychological parameters.Conclusion:In contrast to previous studies, this study found lower anxiety and depression levels in patients with IBD than in HCs. Moreover, DA score was higher in HCs. For the first time, we revealed that DA may be one of the factors leading to sleep disturbance in patients with IBD.Publication Open Access Depression and anxiety have unique contributions to somatic complaints in depression, irritable bowel syndrome and inflammatory bowel diseases(TAYLOR & FRANCIS LTD, 2019-10-02) SAKALLI KANİ, AYŞE; Yanartas, Omer; Kani, Haluk Tarik; Kani, Ayse Sakalli; Akca, Zeynep Nur Demirok; Akca, Erdogdu; Ergun, Serhat; Tezcan, Neslihan; Atug, Ozlen; Imeryuz, Nese; Sayar, KemalOBJECTIVE: In this study we aim to investigate the effects of somatic and related symptoms (SARS), alexithymia, hypochondriasis, anxiety and depression on patients with major depressive disorder, irritable bowel syndrome, inflammatory bowel disease which are the representative diseases of brain gut axis (BGA). METHOD: Sex and age similar groups of participants with major depressive disorder (MDD) (n = 102), irritable bowel syndrome (IBS) (n = 51), inflammatory bowel diseases (IBDs) (n = 54), and control group (n = 67) were included into this study. Depression and IBS were diagnosed according to DSM-5 and ROME 4 criteria, respectively. IBDs were established according to endoscopic, histological, and radiographic investigations. In all participants, somatic and related symptoms were evaluated by self-report scales including Bradford Somatic Inventory (BSI), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Whiteley Index (WI), The 20-item Toronto Alexithymia Scale (TAS-20), Somatosensory Amplification Scale (SAS). RESULTS: BSI, BDI, BAI, WI, TAS-20 and SAS scores were found to be highest in patients with MDD; scores of patients with IBS and IBDs were similar but higher than the control group. Gastrointestinal somatic symptoms including nausea, stomach burning, abdominal ache and stomach swelling were observed in more than half of the patients with MDD. The most common extra-intestinal somatic symptoms were, headache and neck pain and/or tension, and leg pain in IBS patients. However leg pain, weakness and lack of energy, and neck pain/tension were highest in IBDs patients. While the strongest correlation determined was between the BSI and anxiety scores in MDD (p<.001, r = .688) and IBS group; (p<.001, r = .51), in IBDs patients, BSI scores were more significantly correlated with depressive scores instead of anxiety (p<.001, r = .712 vs. r = .705, p<.001). CONCLUSION: Our study demonstrates that SARS are commonly observed in the representative diseases of BGA. Extra-intestinal somatic symptoms are common in IBS, and IBDs, and also gastrointestinal somatic symptoms are common in patients with MDD. Assessment of somatic and related symptoms is quite important in the context of BGA.