Person: ŞANAL TOPRAK, CANAN
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ŞANAL TOPRAK
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Publication Open Access The effect of central sensitization on interlaminar epidural steroid injection treatment outcomes in patients with cervical disc herniation: an observational study(2022-09-01) SAÇAKLIDIR, REKİB; ŞANAL TOPRAK, CANAN; GÜNDÜZ, OSMAN HAKAN; ŞENCAN, SAVAŞ; Sacaklidir R., ŞANAL TOPRAK C., Yucel F. N. , GÜNDÜZ O. H. , ŞENCAN S.© 2022, American Society of Interventional Pain Physicians. All rights reserved.Background: Central sensitization (CS) is a hyperexcitability that is manifested by the increased response of the central nervous system to sensory stimuli. It has been shown that the presence of CS may have a negative effect on the clinical picture in some musculoskeletal diseases and also have a negative effect on spinal procedures. Objectives: To investigate the effect of CS on interlaminar epidural steroid injection (ILESI) treatment outcomes in patients with cervical disc herniation (CDH). Study Design: An observational study. Setting: A university hospital pain management center. Methods: Patients, who underwent ILESI between 2020-2021 due to CDH, were included in the study. The Numeric Rating Scale (NRS-11), Neck Pain and Disability Scale (NPDS), Self-Administered Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS), and Short Form-12 (SF-12) were used for evaluation of patients. Patients were assessed before the procedure, at the first hour, and 3 months after the procedure. The presence of CS was investigated by the Central Sensitization Inventory (CSI). Results: A total of 51 patients were included in the study. Twenty-three of the patients had CS, as assessed by the CSI. Although, patients who underwent ESI, had significantly lower NRS-11, S-LANSS, and NPDS scores, and higher SF-12 scores at all follow-up points. The first and third months, NRS-11, S-LANSS, and NPDS were significantly higher, and SF-12 scores were lower in the CS group compared to patients without CS. Limitations: The short follow-up period and relatively low number of patients can be considered as a limitation. The fact that CS is not evaluated with a more objective method, such as Quantitative Sensory Testing (QST), can be considered as another limitation. Since most clinicians use CSI, so from a \"real world\" perspective the lack of QST may be observed as a strength of the study. The third limitation is that we did not evaluate the patients’ pre-and posttreatment analgesic consumption. Finally, we did not include patients with a history of psychiatric illness, but not evaluating the current psychiatric conditions of the patients could be considered a limitation. Nevertheless, the main strengths of this study are its prospective design and, to our knowledge, it is the first study to explore the effects of CS on cervical ESI treatment. Conclusions: The presence of CS has a negative effect on pain scores, disability, and quality of life in patients undergoing cervical ESI due to CDH.Publication Metadata only Outcome measurement in patients with low back pain undergoing epidural steroid injection(BAYCINAR MEDICAL PUBL-BAYCINAR TIBBI YAYINCILIK, 2019) ŞANAL TOPRAK, CANAN; Ercalik, Tulay; Atalay, Kardelen Gencer; Toprak, Canan Sanal; Gunduz, Osman HakanObjectives: This study aims to evaluate the outcomes of epidural steroid injection (ESI) in patients with low back pain. Patients and methods: This prospective study included a total of 82 patients (51 females; 31 males; mean age 50.8 +/- 14.2 years; range, 17 to 86 years) who underwent ESI due to lumbar disc hernia-induced radiculopathy between September 2014 and May 2015. The Numeric Rating Scale (NRS), Oswestry Disability Index (ODI), Istanbul Low Back Pain Disability Index (ILBPDI), and the Short Form-36 (SF-36) were administered to all patients before and three weeks and three months after ESI. Results: The mean scores of all scales were significantly lower at three weeks and three months following ESI compared to the baseline scores. There were no significant differences between the mean scores at three weeks and three months. The NRS yielded the highest post-ESI change from baseline. Conclusion: Our study results showed that all scales used in this study were effective tools for the evaluation of outcomes of EPI in patients with low back pain. Although the NRS yielded the highest sensitivity for detecting change, evaluating functional state and quality of life is essential for multivariate analyses.Publication Metadata only Servi̇kal di̇sk herni̇asyonunda kuru iğnelemeni̇n İnterlami̇nar epi̇dural steroi̇denjeksi̇yonu tedavi̇ sonuçlarına etki̇si̇(2021-04-08) ŞANAL TOPRAK, CANAN; ŞENCAN, SAVAŞ; GÜNDÜZ, OSMAN HAKAN; YOLCU G., ŞANAL TOPRAK C., ŞENCAN S., GÜNDÜZ O. H.Publication Metadata only The validity and reliability of turkish version of the jenkinssleep scale in rheumatoid arthritis(2015-09-29) ŞANAL TOPRAK, CANAN; GÜNDÜZ, OSMAN HAKAN; DURUÖZ, MEHMET TUNCAY; DURUÖZ M. T., ÜNAL Ç., Ulutatar F., ŞANAL TOPRAK C., GÜNDÜZ O. H.