Person: ÇİPRUT, AYŞE AYÇA
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ÇİPRUT
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AYŞE AYÇA
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Publication Open Access Musical mistuning perception and appraisal in cochlear implant recipients(2023-06-01) YÜKSEL, MUSTAFA; ÇİPRUT, AYŞE AYÇA; Kösemihal E., Yüksel M., CESUR S., Çiprut A.Objective Music is a very crucial art form that can evoke emotions, and the harmonious presence of the human voice in music is an impactful part of this process. As a result, vocals have had some significant effects on contemporary music. The mechanism behind the cochlear implant (CI) recipients perceiving different aspects of music is clear; however, how well they perceive vocal tuning within music it is not well known. Hence, this study evaluated the mistuning perception of CI recipients and compared their performance with normal-hearing (NH) listeners. Study Design, Setting, and Patients A total of 16 CI users (7 cisgender men, 9 cisgender women) and 16 sex-matched NH controls with an average age of 30.2 (±10.9; range, 19-53) years and 23.5 (±6.1; range, 20-37) years, respectively, were enrolled in this study. We evaluated the mistuning ability using the mistuning perception test (MPT) and assessed self-perceived music perception and engagement using the music-related quality-of-life questionnaire. Test performance was measured and reported on the item-response theory metric with a z score ranging from -4 to +4. Results A significant difference in the MPT scores was found between NH and CI recipients, whereas a significant correlation was noted between the music-related quality-of-life questionnaire-frequency subscale and MPT scores. No significant correlations were found between age, CI age, and CI usage duration and MPT performance. Conclusions This study revealed that musical mistuning perception is a limitation for CI recipients, similar to previously evaluated aspects of music perception. Hence, it is important to consider this aspect in the assessment of music perception, enjoyment, and music-based auditory interventions in CI recipients, as vocals are paramount in music perception and recreation. The MPT is a convenient and accessible tool for mistuning assessment in CI and hearing-aid users.Publication Open Access The body image in hearing aid and cochlear implant users in Turkey(2022-11-01) ÇİPRUT, AYŞE AYÇA; Ozturk S., ÇİPRUT A. A.Purpose We investigated the relationship between hearing aid or cochlear implants usage and body image, and quality of life. Methods Of the 96 participants studied, 26 were cochlear implant users, 20 hearing aid users, 20 non-device users with hearing loss, and 30 normal hearing. The inclusion criteria for the study for all groups were subjects 18 years or older with no other physical complaints. The average age of groups and gender distributions were similar. The Body Image Scale (BIS) and World Health Organization Quality of Life Scale were applied to all participants, whereas the International Outcome Inventory for Hearing Aids, Turkish Version, was applied only to device users. Results A significant difference in body image scores was identified between non device users with hearing loss group and normal hearing group, device users group (HA/CI), and cochlear implant users group. In contrast, no significant difference in body image scores between normal hearing group and the device users group was identified. Finally, a positive correlation between body image scores and quality of life scores in all groups was identified. Conclusions Non-device users with hearing loss have a lower body image and quality of life than those in the other groups, and device usage has a positive effect on body image and quality of life.Publication Open Access Observational study of pediatric cochlear implant recipients: Two-year follow-up outcomes(2023-01-01) ÇİPRUT, AYŞE AYÇA; CESUR S., Ciprut A., Terlemez S.Objective: The aim of this study was to evaluate the improvements in quality of life and auditory performance via a descriptive report using patient-related outcomes measures in a group of children with cochlear implants (CI). Methods: This was a longitudinal and retrospective study based on the analysis of patient records of a total of 28 children with CI, 18 of whom had bilateral (64.3%) and 10 had unilateral (35.7%). The study included repeated within-subject measures of Hearing Implants Quality of Life (CuHI-QoL), Categories of Auditory Performance (CAP-II), Speech, Spatial, and Qualities of Hearing scale-Parents’ version (SSQ-P) scales, and Implant Recipient Follow-up (IRF) form at 6-month intervals from baseline up to 24 months. Results: During the 2-year follow-up assessments, all children with CI showed statistically significant improvement over time in their CAP-II, SSQ-P, CuHI-QoL, and IRF scores (p<0.001). The most significant increase in scores occurred within the first six months following the baseline and then continued to increase gradually at a slower pace over time. A moderate negative relationship was found between the age of implantation and SSQ-P and family satisfaction scores of IRF (p<0.05). Conclusions: Family expectations, overall well-being, quality of life, auditory, and verbal skills increase positively with earlier CI intervention. Moreover, the subjective assessment results showed that parents-positive attitudes toward implantation, and willingness to recommend it to others have steadily increased in time. Although the cohort is relatively small and variable, the results offer a descriptive view to outcomes in real-world practice.Publication Open Access A longitudinal study of cortical auditory maturation and implications of the short inter-implant delay in children with bilateral sequential cochlear implants(2023-03-01) ÇİPRUT, AYŞE AYÇA; ATILGAN A., CESUR S., Çiprut A.© 2023 Elsevier B.V.Objective: This longitudinal study aimed to investigate the maturational development of P1 latency and the effects of a short inter-implant delay in children who received bilateral sequential cochlear implants. Materials and methods: Fourteen children (first CI mean age: 1.4 ± 0.4 years and Second CI mean age: 3.3 ± 0.5 years) who had received sequential bilateral cochlear implants during the sensitive period for auditory maturation participated in our study. The speech-evoked cortical P1 response was recorded after the activation of the second CI at four intervals (implant activation, 3 months, 6 months, 12 months) under three listening conditions (first CI, second CI, binaural). Results: Our results showed that the P1 latencies of the second CI reached normative values within 3 months, but did not reach the P1 latency of the first CI until 12 months. We found a strong negative correlation between the inter-implant delay and the P1 latencies of the second CI when the second CI was activated. Conclusion: Changes in cortical auditory responses over time resulted in normal auditory maturation in children with sequential bilateral cochlear implants during the sensitive period. The results also provide evidence that the timing of auditory experience in the first ear during the sensitive period may influence the speed of compensation in children receiving sequential cochlear implants.Publication Open Access P149 The association between the cumulative dose of aminoglycoside exposure and hearing loss in children with cystic fibrosis(2022-06-01) ÇİPRUT, AYŞE AYÇA; Yegit C. Y. , Ergenekon P., Yanaz M., Guliyeva A., Kalyoncu M., Meral O., Selcuk M., Taştan G., Uzunoglu B., Ozturk N., et al.We discuss the excitation of sterile neutrinos in the early universe using general quantum kinetic equations, which also incorporate a possible primordial magnetic field $B$. We find a new contribution to the excitation propability, which has its origin in the shrinkage of the spin vector. In the absence of $B$ nucleosynthesis implies the constraint $\mid \Delta m^2\mid\sin^22\theta_0\lsim 1.6\times 10^{-6}~{\rm eV}^2$ which is more restrictive than previous estimates. We also present examples of possible stringent limits for $B\ne 0$.Publication Open Access Music Perception and Music-Related Quality of Life in Adult Cochlear Implant Users: Exploring the Need for Music Rehabilitation(2024-01-01) ÇİPRUT, AYŞE AYÇA; Akbulut A. A., Karaman Demirel A., Çiprut A.Objectives: Cochlear implant (CI) users face difficulties in accurately perceiving basic musical elements such as pitch, melody, and timbre. Music significantly affects the quality of life (QoL) of CI users. Individually and culturally influenced music perception exceeds psychophysical measures in capturing the subjective music enjoyment of CI users. Understanding the music perception, enjoyment, and habits of CI users is crucial for approaches to improve music-related QoL (MuRQoL). Therefore, this study aims to investigate music perception skills, experiences, and participation in music activities in a large group of adult CI users, and to understand the importance of these factors and their impact on QoL of CI users. Design: This study included 214 CI recipients with diverse auditory experiences who were aged between 18 and 65 years and were unilateral, bimodal, or bilateral users for at least 1 year and 193 normal hearing (NH) controls. All participants completed the information forms and the MuRQoL questionnaire. To assess the impact of music on QoL and identify personalized rehabilitation needs, the scores for each question in both parts of the questionnaire were intersected on a matrix. Data were presented in detail for the CI group and compared between CI and NH groups. Results: A statistically significant difference was found between the matched CI and NH groups in favor of the NH group in terms of music perception and music engagement. Participants who received music education at any point in their lives had significantly higher MuRQoL questionnaire scores. There was no significant relationship found between the duration of auditory rehabilitation, pre-CI hearing aid usage, music listening modality, and MuRQoL questionnaire scores. Unilateral CI users had significantly lower scores in music perception and music engagement subsections compared with bimodal and bilateral CI users. Also, it was found that music had a strong negative impact on QoL in 67/214 of the CI users. Conclusions: Although CI users scored significantly lower than NH individuals on the first part of the questionnaire, which asked about musical skills, enjoyment, and participation in musical activities, findings suggest that CI users value music and music enjoyment just as much. The study reveals the influence of factors such as education level, age, music education, type of hearing loss and auditory rehabilitation on music perception, music enjoyment, and participation in music activities through self-report. The results indicate that for many CI users, music has a strong negative impact on QoL, highlighting the need for personalized music interventions, the inclusion of self-report questionnaires, and music perception tests in clinical evaluations.