Person: AYKAÇ, ZEYNEP ZUHAL
Loading...
Email Address
Birth Date
Research Projects
Organizational Units
Job Title
Last Name
AYKAÇ
First Name
ZEYNEP ZUHAL
Name
3 results
Search Results
Now showing 1 - 3 of 3
Publication Metadata only Analysis of risk factors for sternal surgical site infection: Emphasizing the appropriate ventilation of the operating theaters(CAMBRIDGE UNIV PRESS, 2006) AYKAÇ, ZEYNEP ZUHAL; Yavuz, Serap Simsek; Bicer, Yesim; Yapici, Nihan; Kalaca, Sibel; Aydin, Osman Ozcan; Camur, Gercek; Kocak, Funda; Aykac, Zuhalobjective. To determine the incidence of and identify risk factors for sternal surgical site infection ( SSI). design. Prospective cohort study. Data on potential risk factors, including the type of operating theater and infection data, were collected prospectively and analyzed by multivariate analysis. setting. Siyami Ersek Thoracic and Cardiovascular Surgery Hospital, a 700- bed teaching hospital and the largest center for cardiac surgery in Turkey. The cardiothoracic unit performs approximately 3,000 cardiac operations per year. patients. All adult patients who underwent cardiac surgery with sternotomy between January 14, 2002, and July 1, 2002, and who survived at least 4 days after surgery were included in the study. results. Potential risk factor data were complete for 991 patients. There was sternal SSI in 41 patients ( 4.1%). Female sex, diabetes mellitus, operation performed in the older operating theaters, and duration of procedure exceeding 5 hours were identified as independent risk factors for sternal SSI. conclusions. Female and diabetic patients are at higher risk for sternal SSI and should be followed up carefully after cardiac surgery to prevent the development of sternal SSI. Reducing the duration of surgery could reduce the rate of postoperative sternal SSI. The operating theater environment may have an important role in the pathogenesis of sternal SSI, and appropriate ventilation of the operating theaters would be critical in the prevention of sternal SSI.Publication Metadata only N-Acetylcysteine is ineffective on short-term neuron-specific enolase levels following coronary artery bypass graft surgery(SPRINGER TOKYO, 2012) SARAÇOĞLU, AYTEN; Ugur, Engin H.; Yapici, Nihan; Kudsioglu, Turkan; Ugur, Sinem Y.; Yapici, Mehmet F.; Saracoglu, Ayten; Saracoglu, Kemal T.; Aykac, ZuhalPublication Metadata only Effects of N-acetylcysteine on myocardial ischemia-reperfusion injury in bypass surgery(SPRINGER, 2006) YALÇIN, AHMET SUHA; Orhan, G; Yapici, N; Yuksel, M; Sargin, M; Senay, S; Yalcin, AS; Aykac, Z; Aka, SAMyocardial ischemia-reperfusion injury may complicate coronary artery bypass grafting (CABG) operations. N-Acertylcysteine (NAC) had antioxidant and microcirculatory effects, and inhibits neutrophil aggregation. The aim of this study was to determine the effects of NAC in limiting myocardial ischemia-reperfusion injury in CABG operations. Twenty patients undergoing elective coronary bypass operation with cardiopulmonary bypass were enrolled and randomly assigned to two groups: a control group operated with a routine CABG protocol, and one where NAC was administered intravenously during the operation (NAC group). Blood samples from coronary sinus for tumor necrosis factor-alpha assay, myocardial biopsy specimens for chemiluminescent luminol, and lucigenin measurements of reactive oxygen species were taken. The luminol (specific for .-OH, H2O2, and HOCl- radicals) and lucigenin (specific for O-2(.-)) levels and the difference ratios after reperfusion were significantly lower in the NAC group. Tumor necrosis factor-alpha levels increased in the control group but, in contrast, a significant decrease was detected in the NAC group (P < 0.01). Creatine kinase-MB levels at 6 and 12 hours were singnificantly lower in the NAC group (P = 0.02). N-Acetylcysteine has potential effects to limit ischemia reperfusion injury during CABG operations. We believe that its effects on clinical outcome may be more apparent in patients prone to ischemia-reperfusion injury.