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AYKAÇ, ZEYNEP ZUHAL

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AYKAÇ

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ZEYNEP ZUHAL

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2006 - 200912020 - 20211
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    Oxygen reserve index guided oxygen titration in one lung ventilation with low fresh gas flow
    (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2021) SARAÇOĞLU, AYTEN; Saracoglu, Ayten; Sirzai, Esra Yamansavci; Yildizeli, Bedrettin; Yuksel, Mustafa; Aykac, Zeynep Zuhal
    Background/aim: Continuous oxygen reserve index (ORI) measurement with multiple wave pulse co-oximetry is a noninvasive measurement. The decrease in the ORI trend provides a prediction for the development of hypoxemia and provides information on hyperoxia. Our aim is to determine the effect of ORI-guided oxygen titration on hyperoxemia-mediated morbidity. Materials and methods: Consecutive 120 ASA I-III patients, 18-70 years of age, without severe obstruction or restriction, undergoing one lung ventilation (OLV), were included in the study. Patients were divided into 4 groups. Oxygen titration without ORI monitoring with low-flow anesthesia (1 L/min, Group 1, n = 25) and high-flow anesthesia (4 L/min, Group 2, n = 28). Oxygen titration by ORI monitoring with low flow anesthesia (1 L/min, Group 3, n = 25) and high flow anesthesia (4 L/min, Group 4, n = 25). FiO(2) increased up to 100% if necessary. OLV time, duration of surgery and anesthesia, FiO(2) applied during OLV, oxygen application time (T) over 60%, vital signs, hospital and ICU stay time, and complications were recorded. Results: There was a statistically significant difference in terms of FiO(2) used during OLV (p < 0.05). There was no difference in ORI values (p < 0.05). In Group 3, both PaO2 and SpO(2) were significantly lower than the others both before and during OLV. There was no significant difference in terms of ORI parameters between low flow and high flow anesthesia groups. There was a strong, positive correlation between the duration of hospital stay and FiO(2) used above 80% during OLV. Conclusion: We concluded that ORI-guided thoracic anesthesia may reduce hospital stay and increase patient safety.
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    Analysis of risk factors for sternal surgical site infection: Emphasizing the appropriate ventilation of the operating theaters
    (CAMBRIDGE UNIV PRESS, 2006) AYKAÇ, ZEYNEP ZUHAL; Yavuz, Serap Simsek; Bicer, Yesim; Yapici, Nihan; Kalaca, Sibel; Aydin, Osman Ozcan; Camur, Gercek; Kocak, Funda; Aykac, Zuhal
    objective. To determine the incidence of and identify risk factors for sternal surgical site infection ( SSI). design. Prospective cohort study. Data on potential risk factors, including the type of operating theater and infection data, were collected prospectively and analyzed by multivariate analysis. setting. Siyami Ersek Thoracic and Cardiovascular Surgery Hospital, a 700- bed teaching hospital and the largest center for cardiac surgery in Turkey. The cardiothoracic unit performs approximately 3,000 cardiac operations per year. patients. All adult patients who underwent cardiac surgery with sternotomy between January 14, 2002, and July 1, 2002, and who survived at least 4 days after surgery were included in the study. results. Potential risk factor data were complete for 991 patients. There was sternal SSI in 41 patients ( 4.1%). Female sex, diabetes mellitus, operation performed in the older operating theaters, and duration of procedure exceeding 5 hours were identified as independent risk factors for sternal SSI. conclusions. Female and diabetic patients are at higher risk for sternal SSI and should be followed up carefully after cardiac surgery to prevent the development of sternal SSI. Reducing the duration of surgery could reduce the rate of postoperative sternal SSI. The operating theater environment may have an important role in the pathogenesis of sternal SSI, and appropriate ventilation of the operating theaters would be critical in the prevention of sternal SSI.