Person: DURMUŞ KOCAASLAN, FATMA NİHAL
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DURMUŞ KOCAASLAN
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FATMA NİHAL
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Publication Open Access Evaluation of residual tumors and recurrence rates of malignant melanoma and non-melanoma skin cancer of head and neck region(MARMARA UNIV, FAC MEDICINE, 2019-10-31) SAÇAK, BÜLENT; Durmus Kocaaslan, Fatma Nihal; Alakus, Ali Conor; Sacak, Bulent; Celebiler, OzhanObjective: In this study, we aimed to evaluate residual tumors and recurrence rates of malignant melanoma (MM) and a nonmelanoma skin cancer of (NMSC) head and neck region. Patients and Methods: Medical data of a total of 398 lesions of 323 patients who underwent surgical excision for a basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma (MM) were retrospectively analyzed. All patients were classified according to age, sex, location of the tumor, histopathological diagnosis, lesion diameter, excision diameter, surgical margin status, and residual lesions and recurrence rates. Results: There were 244 lesions (61.3%) in 189 males and 154 lesions (38.7%) in 134 females. The most common type of skin cancer was BCC in 268 lesions (67%), followed by SCC in 122 (31%), and MM in eight (2%), respectively. Recurrence was seen in 3% of the NMSC cases and in 25% of the MM cases. There was a statistically significant correlation between the histopathological diagnosis and recurrence rates. Compared to NMSC, MM cases had a higher risk for recurrence (p=0.029). Conclusion: Our study results suggest that recurrence is associated with the localization and type of the tumor, but not with the age or sex of the patient.Publication Open Access Management of palatal fistulas and a simple surgical algorithm proposal(MARMARA UNIV, FAC MEDICINE, 2020-01-31) DURMUŞ KOCAASLAN, FATMA NİHAL; Kocaaslan, Fatma Nihal Durmus; Memic, Zuhra; Yalcin, Dogus; Celebiler, OzhanObjectives: Despite improved techniques in repair of cleft palate, failure of healing of palatal structures resulting in a palatal fistula is one of the major challenges in the practice of reconstructive surgery. The aim of this study is to evaluate treatment success and failure in patients with palatal fistulas following cleft palate repair. Patients and Methods: Totally 44 patients with a history of cleft palate who underwent surgery for palatal fistula were included in this study undertaken between January 1999 and August 2014. Fistulas were classified as anterior and posterior according to the repair technique and were repaired using one of the following techniques: buccal mucosal flap, tongue flap or mucoperiosteal flap. Results: Success rate for anterior fistulas was 71.42% with tongue flap and 76.92% with mucoperiosteal flap. Success rate for posterior fistulas was 84.62% with mucoperiosteal flap and 75% with buccal mucosal flap. Difference in success rates between the anterior and posterior fistulas was not statistically significant. Conclusion: Our study results suggest the use of mucoperiosteal flaps for both anterior and posterior fistulas smaller than 5mm as the first choice, guided by the principle of replacing absent tissue with similar tissue.Publication Open Access Nasopharyngeal Placement of a Nelaton Suction Catheter in Respiratory Monitoring of Sedated Patients(OXFORD UNIV PRESS INC, 2016-03) DURMUŞ KOCAASLAN, FATMA NİHAL; Kocaaslan, Nihal Durmus; Tuncer, Fatma Betul; Ayanoglu, Hilmi Omer; Celebiler, OzhanPublication Open Access Primary Cutaneous Adenoid Cystic Carcinoma(2020) KESKİN ÖZTÜRK, BEYZA; Caner KAYA;F. Nihal DURMUŞ KOCAASLAN;Zeliha Leyla CİNEL;Beyza KESKİN;Özhan ÇELEBİLERAdenoid cystic carcinoma is a malignant tumor usually localized in the salivary glands. It can also develop in serous glands such as the breast, main bronchi, uterine cervix, Bartholin's gland of the vulva, prostate gland, and external auditory canal. It is more common in the white race. Most of the primary cutaneous adenoid cystic carcinoma cases occur on the scalp. Despite the high rate of metastasis, long-term survival can be observed because the progression of the disease is slow. Distant organ metastases such as lungs, bone, liver and brain have also been reported in the literature at 40%. Its treatment is wide excision of the lesion and demonstration of tumor negative margin in pathological sampling. In this case report, we wanted to present surgical and oncological treatment to a 65-year-old female patient with lung metastasis diagnosed with adenoid cystic carcinoma on the scalp.Publication Open Access Pediatric dysphagia overview: best practice recommendation study by multidisciplinary experts(2022-11-01) KARADAĞ SAYGI, NAİME EVRİM; KARADAĞ, BÜLENT TANER; DURMUŞ KOCAASLAN, FATMA NİHAL; TUTAR, ENGİN; Umay E., Eyigör S., Giray E., Saygi E. K., Karadağ B. T., Kocaaslan N. D., Yuksel D., Demir A. M., Tutar E., Tıkız C., et al.Background Currently, there is no comprehensive and multidisciplinary recommendation study covering all aspects of pediatric dysphagia (PD). This study aimed to generate PD management recommendations with methods that can be used in clinical practice to fill this gap in our country and in the world, from the perspective of experienced multidisciplinary experts. Methods This recommendation paper was generated by a multidisciplinary team, using the seven-step process and a three-round modified Delphi survey via e-mail. First, ten open-ended questions were created, and then detailed recommendations including management, diagnosis, treatment, and follow-up were created with the answers from these questions. Each recommendation item was voted on by the experts as overall consensus (strong recommendation), approaching consensus (weak recommendation) and divergent consensus (not recommended). Results In the 1st Delphi round, a questionnaire of 414 items was prepared based on the experts\" responses to ten open-ended questions. In the 2nd Delphi round, 59.2% of these items were accepted as pre-recommendation. In the 3rd Delphi round, 62.6% of 246 items were accepted for inclusion in the proposals. The final version recommendations consisted of 154 items. Conclusions This study includes comprehensive and detailed answers for every problem that could be posed in clinical practice for the management of PD, and recommendations are for all pediatric patients with both oropharyngeal and esophageal dysphagia.Publication Open Access Comparison of different treatment techniques in the mandibular condyle fracture(TURKISH ASSOC TRAUMA EMERGENCY SURGERY, 2020) DURMUŞ KOCAASLAN, FATMA NİHAL; Kocaaslan, Nihal Durmus; Unal, Beyza Karadede; Ozkan, Melekber Cavus; Karadede, Bersan; Celebiler, OzhanPublication Open Access Impact of ankyloglossia on the language development of children(MARMARA UNIV, FAC MEDICINE, 2021-10-07) DURMUŞ KOCAASLAN, FATMA NİHAL; Baris, Hatice Ezgi; Gunhan, Hakan; Kucuk, Selda; Durmus Kocaaslan, Fatma Nihal; Boran, OerranObjective: Ankyloglossia is a benign anomaly of the tongue which may cause functional limitation. Evidence regarding the impact of ankyloglossia on children's language development is limited. We aimed to evaluate the language development of children born with ankyloglossia. Patients and Methods: Children diagnosed with ankyloglossia were followed up prospectively. Demographic characteristics, degree of ankyloglossia assessed by Hazelbaker score in infancy and its effects on breastfeeding were evaluated. Language development was tested by the Turkish version of the Test of Early Language Development-Third Edition and the Denver II Test at 3-5 years of age. Results: Out of 53 children diagnosed with ankyloglossia, 38 (71.7%) children had language development testing and were included into the study. Significant ankyloglossia was detected in infancy in 10 of these children (26.3%). Median time of exclusively breastfeeding was not different according to the severity of ankyloglossia. All children evaluated with Denver II Test were developmentally normal in all domains. Scores of Test of Early Language Development-Third Edition were not different between children with and without significant ankyloglossia. Conclusion: Long term language development of children with ankyloglossia was not adversely affected. Parents should be appropriately informed and efforts must be paid to prevent unnecessary surgical interventions concerning language delay.Publication Open Access COVID-19 pandemisinin el cerrahisi üzerine etkisi Impact of COVID-19 pandemic on hand injuries(2022-07-01) ÇAVUŞ ÖZKAN, MELEKBER; SARAÇ, ÖMER; KESİMER, MEHMET DENİZ; DURMUŞ KOCAASLAN, FATMA NİHAL; SAÇAK, BÜLENT; AKDENİZ DOĞAN, ZEYNEP DENİZ; ÇAVUŞ ÖZKAN M., Saraç Ö., KESİMER M. D., AKDENİZ DOĞAN Z. D., DURMUŞ KOCAASLAN F. N., SAÇAK B.BACKGROUND: The aim of the study was to evaluate etiologies of hand injuries in emergency department (ED), to compare the etiologies of hand injuries at the time of this study with the previous year, to assess whether novel coronavirus-2019 (COVID-19) pandemic affected the treatment decisions, and to investigate the COVID-19 infection rate within the first 14 days after admission. METHODS: A total of 229 patients admitted to ED with hand injury between March 15 and April 30, 2020, were included in the study. The control group consisted of 439 ED admissions with hand injury in the previous year (March 15-April 30, 2019). Data including age, sex, cause of trauma, treatment, and COVID-19 infection status within 14 days after ED admission were compared between groups. RESULTS: The mean age was 32.30±15.63 years in the study group and 30.85±18.54 years in the control group. The number of patients consulted to the surgery department decreased by 52.6% and the number of patients admitted to ED with hand injuries de-creased by 47.6% during the pandemic, compared to the previous year (p=0.0001). The incidence of home accidents increased and the glass cuts and penetrating/perforating injuries were the most common causes during the pandemic most of which occurred at home. CONCLUSION: The COVID-19 pandemic-mandated social restrictions led to a significant decrease in the number of ED admissions with hand injuries and the type of injuries. The incidence of home accidents increased with more time spent indoors. This study may be a useful guide for ED admissions of hand injury cases and management planning in the current and future pandemics.Publication Open Access 3D evaluation of the effects of traumatic surgical techniques on Vomer bone volume and morphology in the treatment of lip and palate clefts(2022-02-01) ÇELEBİLER, ÖZHAN BEKİR; DURMUŞ KOCAASLAN, FATMA NİHAL; Unal B. K., Kocaaslan N. D., Karadede B., ÇELEBİLER Ö. B.BACKGROUND: Cleft lip/palate (CLP) deformity is the most common congenital facial anomaly. In this study, it was aimed to evaluate the changes in volume and shape of Vomer bone after CLP repair surgery. METHODS: The images of a total of 30 patients aged between 9 and 12 years which were recorded with computed tomography were retrospectively analyzed. The patients were divided into three groups: No syndrome, operated for unilateral CLP group (n=10), no syndrome, operated for bilateral CLP group (n=10), and control group (n=10) with no syndrome, no operation history, or no lip/ palate deformities. Data of the patients were transferred to a software program and a new three-dimensional image was created for the Vomer. RESULTS: There was no statistically significant difference in the Sella-Nasion lengths, Vomer base lengths, and Vomer vertical lengths among the three groups. However, the Vomer bone volume of the patients with bilateral CLP was found to be statistically significantly higher than the control group. CONCLUSION: We can conclude that more bone formation may be observed due to the periosteal reaction following bilateral Vomer flap elevation or during maxillary growth, tension on the palatal flap may be increased new bone formation by pulling the bilateral Vomer flap if it is elevated and sutured palatal mucoperiosteal flap in the early period. Our findings have led us to the conclusion that size and volume of the Vomer bone can be significantly affected by environmental factors. According to the functional matrix theory, scar tissue formation and lack of Vomer-maxilla fusion cannot stimulate the further development of the anterior cranial bones, leading to shorter anterior cranial base.Publication Open Access Fat graft survival inside pocket for silicone implant(MARMARA UNIV, FAC MEDICINE, 2020-05-31) DURMUŞ KOCAASLAN, FATMA NİHAL; Kocaaslan, Fatma Nihal Durmus; Ozkan, Melekber Cavus; Tuncer, Fatma Betul; Bayramicli, MehmetObjective: The aim of this study was to investigate the survival potential of the fat grafts inside the implant capsule in an experimental setting. Materials and Methods: Twenty male Wistar albino rats were used. A two-staged surgical procedure was performed. In the first stage, silicone sheets were placed in the subcutaneous plane on the left side of each rat. On day 60, fat grafts injected into the silicone capsule either by removing the silicone sheaths or leaving the silicone sheaths in their place. In both groups, the same amount of the fat grafts was injected into the right side of the dorsal subcutaneous plane of the rats and they served as their own controls. The findings were evaluated according to the histopathological criteria. Results: There was no statistically significant difference in the inflammatory cell infiltration, fibrosis, and necrotic adipocytes among the groups. Although, the fat viability rate was higher in control groups, there was no statistically significant difference compared to the capsule or silicone groups (p>0.05). Conclusion: Our study results suggest that implant capsule is a hospitable environment and resection of the capsule is unnecessary, if silicone implants are expected to be removed following fat injection.