Person: ALİBAZ ÖNER, FATMA
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ALİBAZ ÖNER
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FATMA
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Publication Metadata only Venous vessel wall thickness in lower extremity is increased in male patients with Behcet's disease(SPRINGER LONDON LTD, 2019) ALİBAZ ÖNER, FATMA; Alibaz-Oner, Fatma; Ergelen, Rabia; Mutis, Aydan; Erturk, Zeynep; Asadov, Ruslan; Mumcu, Gonca; Ergun, Tulin; Direskeneli, HanerVascular involvement, especially in young males, is seen in up to 40% of the patients with Behcet's disease (BD) and is a major cause of mortality and morbidity. In this study, we investigated vessel wall thickness (VWT) and dilatation in lower extremity veins with Doppler ultrasound (US) in male BD patients. Sixty-one male patients with BD, 37 healthy male controls (HC) and 27 male patients, with ankylosing spondylitis (AS), were included in the study. Venous Doppler US was performed by an experienced radiologist blinded to cases. Bilateral common femoral vein (CFV) wall thickness and great/small saphenous vein (SV) dilatations were assessed. All venous measurements were significantly higher in BD compared to AS and HC (p<0.001 for all). Both right and left extremity CFV thicknesses had a high area under the ROC curve (>0.8). Cut-off values for right and left CFV thicknesses for BD was 0.49 and 0.48mm, respectively. High sensitivity and specificities are observed for both measurements (right CFV: sensitivity 81%, specificity 78.4%; left CFV: sensitivity 82.8%, specificity 81.1%). We found increased CFV thickness in BD patients independent of vascular involvement. As a similar change was not observed in controls, increased CFV thickness may be a specific sign of venous inflammation in BD. Our acceptable sensitivity and specificity values of CFV measurements suggest that assessment of femoral vein thickness with US may be a candidate diagnostic tool, especially in young males suspected of BD.Publication Metadata only PREDICTORS AND SEVERITY OF POST-THROMBOTIC SYNDROME IN VASCULAR BEHCET'S DISEASE: RETROSPECTIVE MULTICENTER STUDY(BMJ PUBLISHING GROUP, 2020) ALİBAZ ÖNER, FATMA; Aksoy, A.; Colak, S.; Yagiz, B.; Seniz, B. N.; Omma, A.; Yildiz, Y.; Atas, N.; Ilgin, C.; Sari, A.; Erden, A.; Karadag, O.; Dalkilic, E.; Bolca, N.; Onur, M. N.; Ergelen, R.; Direskeneli, H.; Alibaz-Oner, F.Publication Metadata only Ocular findings and blood flow in patients with Takayasu arteritis: a cross-sectional study(BMJ PUBLISHING GROUP, 2019) ALİBAZ ÖNER, FATMA; Esen, Fehim; Ergelen, Rabia; Alibaz-Oner, Fatma; Celik, Guelce; Direskeneli, Haner; Kazokoglu, HalukBackground/aims Takayasu arteritis (TAK) is a chronic granulomatous vasculitis that can lead to ischaemic ocular complications. We aimed to document ocular complications, ocular blood flow and the association of them with systemic clinical findings in TAK. Material and methods We included 65 patients with TAK (60 female, 5 male, mean age: 41.8 +/- 12.9 years) and 30 healthy subjects (30 female, mean age: 39.0 +/- 7.5 years) in this study. All of the patients had a detailed rheumatological and ophthalmological evaluation. Ocular blood flow in ophthalmic artery (OA) and central retinal artery (CRA) was evaluated with colour Doppler ultrasonography. Results Hypertensive retinopathy was observed in 33.9%, and Takayasu retinopathy was observed in 6.2% of patients. Posterior subcapsular cataracts or a history of cataract surgery was seen in 15.4% of the cases. None of the patients experienced visual loss due to ischaemic or neovascular complications. Patients with TAK had increased resistivity index (RI) in ophthalmic artery (0.75 vs 0.66, p=0.002) and CRA (0.75 vs 0.67, p=0.001). Patients with hypertensive retinopathy had significantly longer disease duration (p=0.016). Ophthalmic artery RI was significantly higher in patients with ipsilateral radial artery pulselessness compared with patients without (0.77 vs 0.68, p=0.031). Conclusion This study reported the lowest prevalence of Takayasu retinopathy and is the only series without permanent visual loss. We documented for the first time that radial artery pulselessness can predict reduction of ipsilateral ocular perfusion. We believe that better management of TAK with current medications reduced ocular complication rates.