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KARĞIN, DİCLE

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KARĞIN

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DİCLE

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Author: AKTAÇ, ŞULE × Has files: true ×

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    PublicationOpen Access
    Effects of Cornus mas L. on lipid peroxidation and anti-oxidative enzyme activity in high fat diet fed rats
    (2023-02-01) KARĞIN, DİCLE; YAVUZ, AYŞE NUR; ÇAM, MUHAMMET EMİN; AKTAÇ, ŞULE; Karğın D., Aktaç Ş., Yavuz A. N., Çam M. E.
    Cornelian cherry (Cornus mas L.) has been used for centuries as a traditional herbal medicine in Europe and Asia. In this study, we aimed to describe the effect of Cornus mas L. (C. mas) on the activity of the antioxidant enzymes and a detoxification agent in rats fed a high-fat diet. Forty-eight adult Sprague Dawley rats were randomly assigned to six groups of eight animals each: Standard diet (Control), High Fat Diet (HFD), HFD + C. mas (200 mg/kg/day; 8 weeks), HFD + Atorvastatin (20 mg/kg/day; 8 weeks), HFD post-treated with C. mas (200 mg/kg/day; 4 weeks), HFD posttreated with Atorvastatin (20 mg/kg/day; 4 weeks). The activity of the antioxidant enzymes, Superoxide dismutase (SOD), Catalase (CAT), Glutathione peroxidase (GPx), detoxification agent glutathione (GSH), and oxidative stress parameter thiobarbituric acid reactive substances (TBARS) were measured in the liver tissues. GPx, SOD, and CAT enzyme levels were decreased in HFD groups compared to the control (p < 0.05). However, Cornus mas L. promoted antioxidant activity by increasing GPx, SOD, and CAT enzymes and It also reduced oxidative stress (as an increase in GSH) both in the HFD + C. mas group and the HFD post-treated C. mas group compared to the HFD group (p < 0.05). Our study showed that feeding a high-fat diet increases oxidative stress. Cornus mas L treatment improves antioxidant enzyme activity and oxidative stress parameters in the liver tissues of rats.
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    PublicationOpen Access
    The relationship between social media use, eating attitude and body mass index among nutrition and dietetic female students: A cross-sectional study
    (ASOC ESPANOLA DIETISTAS NUTRICIONISTAS, 2021-04-06) KARĞIN, DİCLE; Aktac, Sule; Kargin, Dicle; Gunes, Fatma Esra
    Introduction: This study aimed to investigate the relationship between media using habits, frequency and duration, and body mass index on eating attitudes. Material and Methods: The cross-sectional study was conducted with female students who received nutrition and dietetics education in Istanbul. A questionnaire consisting of a socio-demographic questionnaire, Eating Attitude Test (EAT-40), and Social Media Attitude Scale was applied to 1248 female volunteers by the face-to-face interview method. Results: It was found that 35.7% of the participants had abnormal eating attitudes and 89.6% showed a positive attitude towards social media. 93.7% of the group with abnormal eating attitudes indicated a positive attitude towards social media, 0.4% had a negative attitude and the difference was statistically significant (p=0.001). It was observed that a significant difference between EAT-40 and thought of an eating problem, having a social media membership, and spending time on social media (p<0.05). Conclusions: Social media have an effect on nutrition dietetics students on abnormal eating attitude; it did not show a significant effect on BMI.