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CÖMERT ÖZER, ELİF

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Author: CÖMERT ÖZER, ELİF × Subject: atopic eczema ×

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    Netherton syndrome: Temporary response to dupilumab
    (WILEY, 2020) SALMAN, ANDAÇ; Aktas, Meryem; Salman, Andac; Apti Sengun, Ozlem; Comert Ozer, Elif; Hosgoren Tekin, Selcen; Akin Cakici, Ozlem; Demir, Gizem; Ergun, Tulin
    Netherton syndrome (NS) is an orphan disease characterized by congenital ichthyosis, hair abnormalities, and atopy, with limited treatment options. We achieved temporary improvement only during the initial 6 weeks of treatment with dupilumab, which differs from the sustained improvement observed in 2 other recently published cases. Although the clinical presentation of atopy and increased pre-allergic cytokines in NS patients suggest that dupilumab may be beneficial, larger studies are required.