Person: OKUYAN, BETÜL
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OKUYAN
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BETÜL
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Publication Open Access Validation of the Turkish version of the DOSE-Nonadherence measure among patients with cardiometabolic conditions(2022-10-01) AY, NADİYE PINAR; OKUYAN, BETÜL; Yagmur M., Ay P., Sancar M., Voils C. I., Okuyan B.What is known and objective There are no validated self-report measures to assess extent of and reasons for medication nonadherence in the Turkish language. The aim of this study is to evaluate validity and reliability of the Domains of Subjective Extent of Nonadherence Scale, which assesses extent of and reasons for nonadherence in Turkish patients with hypertension, diabetes mellitus and/or dyslipidaemia in community pharmacy settings. Methods The Turkish version of the DOSE-Nonadherence scale was developed through translation and cultural adaption. Psychometric properties of the scale were evaluated in a cross-sectional study among 203 patients who visited six community pharmacies located in Istanbul, Turkey between November 2020 and March 2021. For the extent of nonadherence domain, reliability was estimated through Cronbach\"s alpha, and convergent validity was evaluated with Spearman\"s rank correlation with the validated Turkish version of the Medication Adherence Report Scale (MARS). Reasons for nonadherence were characterized among participants reporting nonadherence to the extent of nonadherence items. The measure was administered at baseline and 2 weeks later to 30 patients to estimate stability of extent scores using the Wilcoxon test and intraclass correlation coefficient. p < 0.05 was set as the level of statistical significance. Results Among the 203 participants (65 male), the median (25th-75th percentiles) age was 59.0 years [51.0-67.0]. Cronbach\"s alpha for the extent of nonadherence scale was 0.86. A moderate negative correlation (r = -0.58; p < 0.001) was found between the extent of nonadherence scores and MARS, supporting convergent validity. The most common reasons for medication nonadherence were forgetfulness (22.5%) and mismatch between the patients\" daily routine and medication taking (17.5%). The intraclass correlation coefficient was 0.97 for extent of nonadherence scores at baseline and 2 weeks (p < 0.001). What is new and conclusion The DOSE-Nonadherence Scale could be used to identify nonadherent patients and their reasons for nonadherence in Turkish patients with chronic cardiometabolic conditions. This scale can be used to evaluate clinical pharmacist-led services to reduce medication nonadherence. Nonadherence could be recorded longitudinally in electronic health records to provide a more accurate picture of medication use. Pharmacists or other providers could administer interventions tailored to patients\" reasons for nonadherence.Publication Metadata only Validation of the Turkish version of medication regimen complexity index among elderly patients(WILEY, 2016) OKUYAN, BETÜL; Okuyan, Betul; Babi, Bedis; Sancar, Mesut; Ay, Pinar; Yucel, Emre; Yucel, Aylin; Izzettin, Fikret VehbiObjectiveThe aim of this study was to validate the Turkish version of the Medication Regimen Complexity Index' (MRCI). MethodsThis validation study has been conducted in prescriptions of the first 100 elderly patients who had visited the pharmacy for their prescription refill to evaluate convergent and divergent validity of the Turkish version. The reliability of the Turkish version was assessed with inter-rater and test-retest analysis after its translation and cultural adaptation. ResultsThe mean age of the 100 patients (53 women) was 74.9years (SD=7.58, 65-95). The scale showed high inter-rater reliability and test-retest reliability for the total and subscale scores (p<0.05). A strong and positive correlation between the number of medications in a prescription and the total Medication Regimen Complexity Index scores (r=0.930, p<0.001) was determined. There were no statistically significant differences between age, gender and MRCI scores (p>0.05). ConclusionThese results show that the Turkish version of MRCI is a reliable and valid tool in elderly patients.Publication Metadata only Reliability and validity of the turkish version of the family caregiver medication administration hassles scale(2023-04-01) SANCAR, MESUT; AY, NADİYE PINAR; OKUYAN, BETÜL; Kingir Z. B., SANCAR M., AY N. P., Demirtunc R., Nuhoglu C., Misirli C. H., OKUYAN B.Background: The Family Caregiver Medication Administration Hassles Scale (FCMAHS) was developed to evaluate the hassles and concerns experienced by family caregivers in medication administration.Objective: This study aimed to evaluate the reliability and validity of the Turkish version of the Family Caregiver Medication Administration Hassles Scale (FCMAHS-TR).Methods: The FCMAHS-TR was developed after translation, cultural adaptation, and a pilot study. The cross-sectional study was conducted among family caregivers (=18 years) in community pharmacies. Test-retest reliability analysis, exploratory factor analysis (EFA), and confirmatory factor analysis (CFA) were performed. Hypothesis testing was used for the assessment of construct validity.Results: The majority (68.7%) of the family caregivers were female (n = 470). In the test-retest reliability analysis (n = 30), the ICC value was 0.917 (P < 0.001). In EFA analysis (n = 251), the Kaiser-Meyer-Olkin (KMO) measure was 0.799, 62.6% of the total variance was explained by five factors including eighteen items, and Cronbach\"s alpha was 0.836. According to CFA (n = 219), the root mean square error of approxi-mation (RMSEA) was 0.0654, and the comparative fit index (CFI) was 0.918. In construct validity, family caregivers with low reading ability of health-related materials and with high care burden had significantly higher median scores for all the factors of the FCMAHS-TR (P < 0.05 for all).Conclusions: The FCMAHS-TR can be used to evaluate the hassle and concerns experienced by family caregivers in medication administration. This scale can be used by healthcare professionals to identify family caregivers who need individualized interventions for medication adminis-tration hassles.Publication Metadata only Medication adherence barriers in Turkish patients with chronic diseases(2022-12-01) SANCAR, MESUT; AY, NADİYE PINAR; OKUYAN, BETÜL; Yagmur M., SANCAR M., Ay P., Abdi A., Samuelyan N., OKUYAN B.Publication Metadata only Investigation of Physicians' Perspectives of Drug Promotional Activities(AVES PRESS LTD, 2016) OKUYAN, BETÜL; Akici, Ahmet; Kilboz, Mehmet Murat; Mollahaliloglu, Salih; Ozgulcu, Senay; Alkan, AliObjective: Pharmaceutical company promotional activities (PCPAs) are listed among the factors that influence the prescribing behavior of physicians. This study aimed to determine the opinions of family physicians (FPs) and specialist physicians (SP) on the impact of these activities. Methods: A survey comprising 1062 FPs working in primary health centers and 562 SPs working in public hospitals at different cities in Turkey was conducted. The questions thoroughly evaluated physicians' approaches toward PCPAs, particularly drug promotional activities. Answers were evaluated with respect to the demographic and occupational characteristics of physicians. Results: Based on the statements of participants, 82.8% of FPs and 88.6% of SPs declared that physicians always or sometimes are influenced by PCPAs. Percentage of SPs who declared themselves as always or sometimes influenced by PCPAs was significantly higher than that of FPs (p=0.006). Overall, 56.3% of FPs and 43.3% of SPs were visited >5 times during the last 5 working days by pharmaceutical sales representatives. When considering features of drugs prescribed after PCPAs, both FPs and SPs declared that these drugs were cheaper (52.8% and 47.8%, respectively) and safer (52.7% and 49.3%, respectively) than their alternatives. Conclusion: Physicians' statements showed that they were often visited by pharmaceutical sales representatives and highly influenced by PCPAs. Differences with respect to the experiences and approaches of FPs and SPs regarding this issue are critical factors warranting careful consideration of a rational PCPA implementation.Publication Metadata only Turkish Validation of Patient Satisfaction Towards Patient Oriented Pharmacy Services Questionnaire in Patients with Chronic Disease(AVES PRESS LTD, 2016) OKUYAN, BETÜL; Okuyan, Betul; Hucum, Hakan; Sancar, Mesut; Ay, Pinar; Izzettin, Fikret VehbiObjective: The aim of the study was to validate the Turkish version of the patient satisfaction questionnaire that evaluated satisfaction of patients with chronic diseases regarding pharmacy services. Methods: The present study was conducted between September 2015 and November 2015 among patients who had chronic diseases at least for 6 months and applied to community pharmacies. After appropriate language translation, pre-test, test-retest validity, and factor analysis were conducted. Results: The mean age of 154 patients (91 male, 63 female) was 58.6 +/- 13.8 years. The mean score of the Patient-Oriented Pharmacy Services Questionnaire (PSPSQ) 2.0 was 3.29 +/- 0.47, and the Cronbach's alpha coefficient was 0.944. A strong correlation was determined between the test-retest validity of the total and subscale scores (p<0.001). Three domains (quality of care, patient-pharmacist relationship, and overall satisfaction) were obtained in factor analysis of PSPSQ 2.0, as in the original study. Conclusion: In the present study, the Turkish form of PSPSQ 2.0 was determined to be a reliable and valid scale to assess patients' satisfaction regarding patient-oriented pharmacy services.Publication Metadata only Translation and psychometric evaluation of the Turkish version of the pharmacy students' perceptions of preparedness to provide pharmaceutical care scale(GOVI-VERLAG PHARMAZEUTISCHER VERLAG GMBH, 2016) OKUYAN, BETÜL; Okuyan, B.; Sancar, M.; Ay, P.; Demirkan, K.; Apikoglu-Rabus, S.; Izzettin, F. VehbiThe aim of the study is to conduct the psychometric evaluation of the Turkish version of the Pharmacy Students' Perceptions of Preparedness to Provide Pharmaceutical Care (PREP) scale. The present study was conducted at three faculties of pharmacy among fifth-year students during a three-month period in 2015. After the translation process, the Turkish version was developed. Psychometric evaluation consisted of the calculation of inter-rater and test-retest reliability and factor analysis. The mean age of 184 students (71.2% of female) was 23.74 +/- 1.07. The mean score of the Pharmacy Students' PREP scale was 4.54 +/- 1.00 and the Cronbach's alpha was 0.971. Inter-rater and test-retest reliability and factor analysis were also in concordance with the literature. In the present study, the Turkish version of Pharmacy Students' Perceptions of Preparedness to Provide Pharmaceutical Care Scale has been determined to be a reliable and validated tool to assess students' perceptions of preparedness to provide pharmaceutical care.Publication Open Access Factors associated with Turkish pharmacists' intention to receive COVID-19 vaccine: an observational study(SPRINGER, 2022-02) OKUYAN, BETÜL; Okuyan, Betul; Bektay, Muhammed Yunus; Demirci, Muhammed Yasir; Ay, Pinar; Sancar, MesutBackground Pharmacists have been taking part in vaccination services during the COVID-19 pandemic. However, research identifying pharmacists' intention to get COVID-19 vaccine is limited. Aim The objective of this study was to determine the intention to receive COVID-19 vaccine and to identify the factors related to it based on the Health Belief Model framework among Turkish pharmacists. Method This is an observational study conducted between December 2020 and January 2021. The online survey was sent to all hospital and community pharmacists working in Turkey. Transtheoretical Model of Behaviour Change and Health Belief Model were used for the development of the questionnaire. Univariate and multivariate logistic regression analyses were conducted to identify factors associated with the intention to receive COVID-19 vaccine. Results Among all participants (n = 961), 74.7% had an intention to receive the COVID-19 vaccine. In model 1, perceived susceptibility, perceived severity, perceived benefits, and perceived barriers were associated with their intention to receive the COVID-19 vaccine (p < 0.05). In model 2, the intention to receive COVID-19 vaccine was associated with being male, years of experience in the professional field, not having contracted COVID-19, having a pharmacy staff who had contracted COVID-19, and having had received seasonal flu shot within the previous year (p < 0.05). Conclusion This study highlights the factors related to the intention of the pharmacists to receive COVID-19 vaccines. Health Belief Model is the strongest predictor for vaccination intention and could be used to develop behavioural change techniques to promote vaccination.Publication Open Access Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic(TURKISH PHARMACISTS ASSOC, 2021-09-01) OKUYAN, BETÜL; Turker, Meltem; Sancar, Mesut; Demirtunc, Refik; Ucar, Nazlican; Uzman, Osman; Ay, Pinar; Kozan, Omer; Okuyan, BetulObjectives: This study aimed to evaluate the validity and reliability of an oral anticoagulation knowledge (OAK) test in Turkish patients on warfarin therapy at an anticoagulant outpatient clinic. Materials and Methods: This study was conducted at an ambulatory anticoagulation clinic and included patients older than 18 years who had been using warfarin for at least six months. Patients' demographic and clinical data were collected. Internal consistency was calculated using the Kuder-Richardson 20 (KR-20) coefficient, and the test-retest reliability of the Turkish version of the OAK test was assessed. Results: Patients' mean age was 59.83 +/- 11.93 (26-90) years (n=240; 133 women). The mean score of the OAK test was 14.19 +/- 3.01. The test-retest reliability of the scale (n=30) was moderate for the total score (p<0.001). The KR-20 value, a measure of internal consistency, was 0.671. Patients of a younger age and higher educational level were more likely to have higher levels of anticoagulation knowledge than patients of an older age and lower education level (p<0.05 for both comparisons). Conclusion: The Turkish version of the OAK test can be used to determine the patients' knowledge on oral anticoagulation.