Person:
AKSU, MEHMET BURAK

Loading...
Profile Picture

Email Address

Birth Date

Research Projects

Organizational Units

Organizational Unit

Job Title

Last Name

AKSU

First Name

MEHMET BURAK

Name

Search Results

Now showing 1 - 3 of 3
  • Publication
    Fabrication, characterization and investigation of antibacterial activity of propolis substituted sodium alginate tissue scaffolds using three-dimensional (3d) printing technology
    (2021-06-05) UZUN, MUHAMMET; SU TORUN, SENA; ULAĞ, SONGÜL; AKSU, MEHMET BURAK; GÜNDÜZ, OĞUZHAN; CESUR, SÜMEYYE; Aarancı K., Uzun M., Su Torun S., Cesur S., Ulağ S., Amin A., Güncü M. M., Aksu M. B., Kolaylı S., Silva J., et al.
  • PublicationOpen Access
    Fabrication of gentamicin sulfate-loaded 3d-printed polyvinyl alcohol/sodium alginate/gelatin-methacryloyl hybrid scaffolds for skin tissue replacement
    (2023-01-01) ULAĞ, SONGÜL; ŞAHİN, ALİ; AKSU, MEHMET BURAK; GÜNDÜZ, OĞUZHAN; Izgordu M. S., Ayran M., ULAĞ S., Yildirim R., Bulut B., ŞAHİN A., Guncu M. M., AKSU M. B., GÜNDÜZ O.
    3D-printed scaffolds can better mimic the function of human skin, both biologically and mechanically. Within the scope of this study, the effect of the addition of different amounts (10, 15, 20 mg) of gentamicin sulfate (GS) to a 10 mL solution of natural and synthetic polymers is investigated. Sodium alginate (SA), gelatin-methacryloyl (GelMA), and polyvinyl alcohol (PVA) are chosen as bioactive materials. The surface morphology and pore structures are visualized by scanning electron microscopy (SEM). According to the results, it is observed that the pore sizes of all scaffolds are smaller than 270 µm, the lowest value (130 µm) is obtained in the scaffold loaded with 15 mg GS, and it also has the highest tensile strength value (12.5 ± 7.6 MPa). Similarly, it is observed that the tensile strength (9.7 ± 4.5 MPa) is high in scaffold loaded with 20 mg GS. The biocompatibility test is performed with fibroblast cells, and the results show that the scaffolds are biocompatible with cells. The antibacterial test is carried out against the S.aureous and E. coli and the results indicate that all GS-loaded scaffolds demonstrate antibacterial activity.
  • Publication
    Uv curable and long lasting antimicrobial paint coating
    (2023-10-27) AKSU, MEHMET BURAK; Aksu M. B.
    The harmful effects of microorganisms seriously threaten human health and life. Since prehistoric times, many diseases are caused by microorganisms and such types of diseases are still increasing. Antimicrobial resistance is the one of the main concern about the fight against to bacteria. Biocidal products show chemical and biological effects against harmful microorganisms, preventing their growth and biofilm formation. There are many biocidal compounds used against to bacteria. One of them is the cationic polymer that possess hydrophobicity and polar groups (cationic charge) to mimic the host defense peptides’ structure. Polymeric antibacterial agents represent new developing direction in this field and offer great promise for enhancing activity. Here, we synthesized UV curable quaternary monomers/oligomers possessing alkyl functionality. After addition into the UV varnish formulation, coated surfaces showed the 100% killing and repeated cycle efficiency against to E.coli and S.aureus.