Person: GÜNEŞ, FATMA ESRA
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GÜNEŞ
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FATMA ESRA
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Publication Metadata only Evaluation of a Standardized Bakery Product (SUTMEK) as a Potential Tool for Baked-Milk Tolerance and Immunotherapy Research Studies(KARGER, 2019) ÖZEN, AHMET OĞUZHAN; Kiykim, Ayca; Karakoc-Aydiner, Elif; Gunes, Esra; Nain, Ercan; Ogulur, Ismail; Yazici, Duygu; Aktac, Sule; Bicer, Ayse Humeyra; Sackesen, Cansin; Baris, Safa; Ozen, AhmetBackground and Objectives: About 65-80% of children with IgE-mediated cow's milk allergy (CMA) can tolerate extensively heated milk. We have invested in the mass fabrication of a test product containing milk protein baked at 180 degrees C for 30 min (SUTMEK-milk) and a milk-free placebo (SUTMEK-placebo) to carry out a standardised double-blind placebo-controlled food challenge (DBPCFC) test in patients with CMA. Methods: We studied children with IgE-mediated CMA between 13 and 48 months of age. Specific IgEs (spIgE) to milk proteins were quantified. A DBPCFC with our bakery products was performed, and factors determining reactivity to extensively heated milk were evaluated. We also tested the applicability of SUTMEK products in baked-milk oral immunotherapy in a pilot assessment. Results: We studied 15 children (8 girls, 7 boys) with a median age of 26 months (range: 13-48 months). Nine (60%) patients tolerated a challenge with extensively heated milk, while 6 (40%) were found reactive (anaphylaxis: 2, wheezing: 2, urticaria: 2). spIgE to milk, alpha-lactalbumin, and casein, and the wheal diameter on skin prick testing were higher in the reactive group than the tolerant groups (p = 0.001, p = 0.001, p = 0.002, and p = 0.048, respectively). Receiver-operating characteristic curve analyses yielded the following cut-off values for spIgEs that would predict a reactivity to extensively heated milk; milk: 25 kU/L (area under curve, AUC: 0.981), casein: 32 kU/L (AUC: 0.983), and alpha-lactalbumin: 17 kU/L (AUC: 0.981). Nine patients have tolerated well a continued daily consumption of SUTMEK-milk or -placebo for 6 months at the desired doses. Conclusions: Our bakery products were successfully used in DBPCFC studies and qualified as an acceptable tool for use in the research of interventional tolerance induction. Although spIgE appears useful in determining children at high risk of reacting to extensively heated milk, the predictive cut-off values are still far from being perfect. (c) 2018 S. Karger AG, BaselPublication Metadata only Sabri Ülker Vakfı - Yemekte denge besin tüketim sıklığı ve miktarı araştırması - II sonuçları(2019-10-12) GÜNEŞ, FATMA ESRA; AKTAÇ, ŞULE; SABUNCULAR, GÜLEREN; KAMARLI ALTUN H., GÜNEŞ F. E., AKTAÇ Ş., SEREMET KÜRKLÜ N., ÖZEN S., SABUNCULAR G., SUNA G., ARCA D. M., ŞEN N., ERDİN S.Publication Metadata only IMPLEMENTATION OF A BALANCED NUTRITION EDUCATION PROGRAM AMONG PRIMARY SCHOOL CHILDREN IN TURKEY(ELSEVIER SCIENCE INC, 2018) GÜNEŞ, FATMA ESRA; Besler, Halit Tanju; Meseri, Reci; Kucukerdonmez, Ozge; Sahin, Habibe; Cicek, Betul; Gunes, Esra; Aktac, Sule; Aksoy, Burcu; Mutus, BegumPublication Metadata only Relation between Eating Habits and a High Body Mass Index among Freshman Students: A Cross-Sectional Study(ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2012) GÜNEŞ, FATMA ESRA; Gunes, Fatma Esra; Bekiroglu, Nural; Imeryuz, Nese; Agirbasli, MehmetObjectives: This study aimed to examine the relation between eating habits and a high body mass index (BMI) in first-year freshman university students and included 2525 freshman university students 18 to 22 years old from a Turkish population. Methods: in this study, 48% of the students were men. They were asked to complete a questionnaire on their dietary habits including the frequency of their consumption of individual food items, demographic data, and smoking habit. Results: The effects of eating habits on increased BMI (>= 25) were analyzed. Of 2259 subjects included in the analyses, 322 were overweight or obese and 1937 had normal and thin BMI (<25). Multivariate analyses identified male gender, recent weight change, and high number of meals as independent predictors of obesity/overweight. Frequent consumptions of beer, alcoholic drinks other than beer and wine (e.g., spirits including whisky, gin, raid, vodka), coffee, tea, coke, red meat, variety meat, and eggs were associated with a significantly higher risk of obesity/overweight, whereas frequent consumption of snacks was associated with a low risk. Conclusions: Findings of further studies, possibly taking into consideration the absolute quantities of consumption along with cultural and local issues, would guide the adoption of healthier feeding behaviors in this particular age group.Publication Metadata only Evaluation of Nutrition Knowledge of Pregnant Women before and after Nutrition Education according to Sociodemographic Characteristics(TAYLOR & FRANCIS INC, 2018) KARĞIN, DİCLE; Aktac, Sule; Sabuncular, Guleren; Kargin, Dicle; Gunes, Fatma EsraThe aim of this cross-sectional study is to evaluate the effect of nutrition education on nutritional knowledge levels of pregnant women. The study was undertaken on a sample of pregnant women (i = 743) attending health centers in Istanbul for prenatal care. Nutrition knowledge scores were significantly higher in posttest (23.0) than pretest (16.0) after receiving nutrition education (p < .001). Significant differences in pretest (p < .05) but not posttest (p > .05) scores were found for factors, such as education level, work status, and the number of pregnancies; significant differences in both test scores were found for age and nutrition information (p < .05). In conclusion, pregnant women need to be given adequate and appropriate nutrition education for maternal and child health according to sociodemographic characteristics.Publication Metadata only The relationship between eating attitude and behaviors with self-esteem of the university students(CUMHURIYET UNIV TIP FAK PSIKIYATRI ANABILIM DALI, 2015) GÜNEŞ, FATMA ESRA; Gunes, F. Esra; Calik, K. Burcu T.Objective: The purpose of this study is to determine the relationship between eating attitude and behaviors, self-esteems of the university students due to their age, psychosocial issues related to the environment. Methods: For his purpose, it was evaluated the eating attitude and behaviors in two different faculties of the same university (n=450). A cross-sectional random sampling method with the questionnaire was performed including demographic information, the Eating Attitudes Test and the Rosenberg Self-Esteem Test was administered. Results: As a result of statistical analysis a statistically significant difference of the eating attitude test scores with age, weight and average height. It didn't show significant difference between the mean scores of BMI values and mean scores of self-esteem levels. The students were grouped according to cut-off scores of the Eating Attitudes Test (EAT-40) and detected the statistical significant differences between the means of Rosenberg Self-Esteem Test subgroups scores (the self-esteem levels, relying on other people, interpersonal relationships to threats, participate in discussions and psychic isolation). Conclusion: Consequently, the significant relationship was not observed among students studying in different department of education who have eating disorders about their self-esteem risk. Students which studying in health-related department were more sensitivity than other group in the evaluation of eating attitudes and behaviors.