Person: GÜNEŞ, FATMA ESRA
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GÜNEŞ
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FATMA ESRA
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Publication Metadata only Evaluation of a Standardized Bakery Product (SUTMEK) as a Potential Tool for Baked-Milk Tolerance and Immunotherapy Research Studies(KARGER, 2019) ÖZEN, AHMET OĞUZHAN; Kiykim, Ayca; Karakoc-Aydiner, Elif; Gunes, Esra; Nain, Ercan; Ogulur, Ismail; Yazici, Duygu; Aktac, Sule; Bicer, Ayse Humeyra; Sackesen, Cansin; Baris, Safa; Ozen, AhmetBackground and Objectives: About 65-80% of children with IgE-mediated cow's milk allergy (CMA) can tolerate extensively heated milk. We have invested in the mass fabrication of a test product containing milk protein baked at 180 degrees C for 30 min (SUTMEK-milk) and a milk-free placebo (SUTMEK-placebo) to carry out a standardised double-blind placebo-controlled food challenge (DBPCFC) test in patients with CMA. Methods: We studied children with IgE-mediated CMA between 13 and 48 months of age. Specific IgEs (spIgE) to milk proteins were quantified. A DBPCFC with our bakery products was performed, and factors determining reactivity to extensively heated milk were evaluated. We also tested the applicability of SUTMEK products in baked-milk oral immunotherapy in a pilot assessment. Results: We studied 15 children (8 girls, 7 boys) with a median age of 26 months (range: 13-48 months). Nine (60%) patients tolerated a challenge with extensively heated milk, while 6 (40%) were found reactive (anaphylaxis: 2, wheezing: 2, urticaria: 2). spIgE to milk, alpha-lactalbumin, and casein, and the wheal diameter on skin prick testing were higher in the reactive group than the tolerant groups (p = 0.001, p = 0.001, p = 0.002, and p = 0.048, respectively). Receiver-operating characteristic curve analyses yielded the following cut-off values for spIgEs that would predict a reactivity to extensively heated milk; milk: 25 kU/L (area under curve, AUC: 0.981), casein: 32 kU/L (AUC: 0.983), and alpha-lactalbumin: 17 kU/L (AUC: 0.981). Nine patients have tolerated well a continued daily consumption of SUTMEK-milk or -placebo for 6 months at the desired doses. Conclusions: Our bakery products were successfully used in DBPCFC studies and qualified as an acceptable tool for use in the research of interventional tolerance induction. Although spIgE appears useful in determining children at high risk of reacting to extensively heated milk, the predictive cut-off values are still far from being perfect. (c) 2018 S. Karger AG, BaselPublication Metadata only Nutrients in schizophrenia: A focus on the pathophysiological pathway(Pacini Editore S.p.A./AU-CNS, 2021) GÜNEŞ, FATMA ESRA; Akduman G., Kurtbeyoglu E., Gunes F.E.Objectives The aim of this article is to explain the nutrients that play an active role in the pathophysiology of schizophrenia. Methods This paper is a narrative literature review of relevant articles and prior works that have been central to the topic including the active nutrients in the pathophysiology of schizophrenia. Results The findings are compiled under six headings. The changes in the antioxidant defense system, dopamine pathway, serotonin pathway, gamma-aminobutyric acid (GABA) pathway, glutamate pathway, the endocannabinoid system, and metabolomic profile were investigated in relation to nutrients. Conclusions This review provides an update of scientific knowledge on the growing role of nutrition in schizophrenia. Nutrient deficiencies that occur frequently in these patients should be followed and eliminated to ensure the correct functioning of the pathophysiological pathways of the disease. © 2021 Pacini Editore S.p.A.. All rights reserved.Publication Metadata only Nutritional label use among patients with type 1 diabetes mellitus(Romanian Society of Diabetes, Nutrition and Metabolic Diseases, 2021) CEBECİ, AYBİKE; Cebeci A., Aktac S., Keskin S., Senguzel S., Gunes F.E.Background and Aims: In this study, it was aimed to evaluate the nutritional label use of individuals with type 1 DM. Material and Method: This cross-sectional descriptive study was conducted in November 2017 - June 2018. Diabetic individuals were reached through hospitals and social networks. The study was conducted with 105 (64 female, 41 male) individuals with type 1 DM living in Istanbul. A questionnaire about sociodemographic characteristics, biochemical parameters, medical treatment, food label reading status, food label reading reasons were applied in the study. Data were analyzed using SPSS V 16.0 program. Results: 85.7% of the participants read the food label. No significant difference was found when age group and nutritional label reading status were examined (p > 0.05). Besides, information was given to 67.6% of the participants about reading the nutritional label. A significant association was found between nutritional label reading knowledge and carbohydrate counting application and stages (P=0.0001). However, there was no significant difference between biochemical parameters and reading label status (p>0.05). Conclusions: Nutritional label reading should be mentioned more in the medical nutrition therapy and diabetes education. © 2021 The Authors. Romanian Journal of Diabetes, Nutrition and Metabolic Diseases published by Sanatatea Press Group on behalf of the Romanian Society of Diabetes Nutrition and Metabolic Diseases. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY-NC-ND 3.0).Publication Metadata only Sabri Ülker Vakfı - Yemekte denge besin tüketim sıklığı ve miktarı araştırması - II sonuçları(2019-10-12) GÜNEŞ, FATMA ESRA; AKTAÇ, ŞULE; SABUNCULAR, GÜLEREN; KAMARLI ALTUN H., GÜNEŞ F. E., AKTAÇ Ş., SEREMET KÜRKLÜ N., ÖZEN S., SABUNCULAR G., SUNA G., ARCA D. M., ŞEN N., ERDİN S.Publication Metadata only IMPLEMENTATION OF A BALANCED NUTRITION EDUCATION PROGRAM AMONG PRIMARY SCHOOL CHILDREN IN TURKEY(ELSEVIER SCIENCE INC, 2018) GÜNEŞ, FATMA ESRA; Besler, Halit Tanju; Meseri, Reci; Kucukerdonmez, Ozge; Sahin, Habibe; Cicek, Betul; Gunes, Esra; Aktac, Sule; Aksoy, Burcu; Mutus, BegumPublication Metadata only Relation between Eating Habits and a High Body Mass Index among Freshman Students: A Cross-Sectional Study(ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2012) GÜNEŞ, FATMA ESRA; Gunes, Fatma Esra; Bekiroglu, Nural; Imeryuz, Nese; Agirbasli, MehmetObjectives: This study aimed to examine the relation between eating habits and a high body mass index (BMI) in first-year freshman university students and included 2525 freshman university students 18 to 22 years old from a Turkish population. Methods: in this study, 48% of the students were men. They were asked to complete a questionnaire on their dietary habits including the frequency of their consumption of individual food items, demographic data, and smoking habit. Results: The effects of eating habits on increased BMI (>= 25) were analyzed. Of 2259 subjects included in the analyses, 322 were overweight or obese and 1937 had normal and thin BMI (<25). Multivariate analyses identified male gender, recent weight change, and high number of meals as independent predictors of obesity/overweight. Frequent consumptions of beer, alcoholic drinks other than beer and wine (e.g., spirits including whisky, gin, raid, vodka), coffee, tea, coke, red meat, variety meat, and eggs were associated with a significantly higher risk of obesity/overweight, whereas frequent consumption of snacks was associated with a low risk. Conclusions: Findings of further studies, possibly taking into consideration the absolute quantities of consumption along with cultural and local issues, would guide the adoption of healthier feeding behaviors in this particular age group.Publication Metadata only Evaluation of malnutrition risk of inpatients in a research and training hospital: A cross-sectional study(ELSEVIER, 2021) İSLAMOĞLU, AYŞE HÜMEYRA; Celik, Zehra Margot; Islamoglu, Ayse Humeyra; Sabuncular, Guleren; Toprak, Hatice Selcen; Gunes, Fatma EsraBackground & aims: Malnutrition is one of the most important factors affecting the prognosis of inpatients. The aim of this study is to determine the malnutrition risk of hospitalized patients and to examine the relationship between the presence of malnutrition and other parameters. Methods: The study included 162 inpatients over the age of 25 who were staying in the hospital's internal medicine service for 7 days or more and who volunteered to participate in the study. A demographic-information questionnaire, consisting of 5 sections, a 24-h food recall record, NRS-2002, NRI and Beck Depression Inventory was given to patients during bedside interviews. After obtaining the necessary permission, the anthropometric measurements and biochemical parameter values of the patients were taken from their files. All statistical analyzes were performed by researchers with the SPSS package program. Results: Of 162 patients (48.8% female, 51.2% male), 24.7% were at risk for malnutrition according to NRS-2002 and 66.7% of the patients were not depressive, based on the Beck Depression Inventory scale. The malnutrition risk was higher (60.0%) in patients who had been hospitalized for more than 15 days (p = 0.010). The majority of those with malnutrition had no problems preventing them from eating (32.5%), were found to be not depressive (52.5%) and were in the normal range of body mass index (57.5%) (p = 0.002, p = 0.034, p = 0.001; respectively). Nutrient intake was lower in patients with a higher malnutrition risk, but the difference was insignificant (p > 0.05). Albumin levels (p = 0.028) and total protein levels (p = 0.015) were significantly lower in patients who were at risk of malnutrition. While overweight patients showed higher levels of serum albumin (p < 0.001), CRP levels were found to be lower in overweight patients (p < 0.001). Conclusions: It was found that the majority of patients with malnutrition were in the normal range for BMI. Nutritional intake and biochemical parameters should be followed closely in patients who are at risk of malnutrition. Depression can be a cause for insufficient nutrition and should be evaluated, particularly in patients whose length of hospital stay is greater than 7 days. (C) 2020 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.Publication Metadata only The effects of dietary changes on bone markers in postmenopausal vertebral osteopenia(CHURCHILL LIVINGSTONE, 2020) İSLAMOĞLU, AYŞE HÜMEYRA; Islamoglu, A. Humeyra; Garipagaoglu, Muazzez; Bicer, H. Selcen; Kurtulus, Duygu; Ozturk, Mustafa; Gunes, F. EsraBackground & aims: Nutrition is one of the most important environmental factors affecting the formation of osteopenia. The purpose of this study was to investigate the effects of dietary changes on bone formation and bone resorption markers of postmenopausal women with vertebral osteopenia. Methods: In this study, 108 women with postmenopausal vertebral osteopenia were included. Patients were observed for a month to identify their regular nutritional status. Before intervention, blood and urine samples were taken from all patients. Then, 2-day food consumption records were taken and the patients were divided into 4 groups. Different types of diets (opposite of their regular diets) were prepared for these groups (1: control, 2: reduced-carbohydrate, 3: reduced-protein, 4: reduced-sodium) and followed for 3 months. At the end of follow-ups, blood and urine samples were taken again and changes in osteocalcin (OC) and N-terminal telopeptide (NTX) levels were examined. Results: According to biochemical analysis, there was a significant decrease (p < 0,001) in OC levels in reduced protein group and an increase (p > 0,05) in reduced carbohydrate group. When NTX levels were assessed, a significant decrease (p < 0.001) in the reduced carbohydrate group and a significant increase in the reduced protein group (p < 0.05) were found. Conclusion: Our findings show that reduced carbohydrate diet protected whereas, reduced protein diet negatively affected bone health. Osteopenic individuals were thought to be able to improve bone health and their quality of life by early dietary intervention. (C) 2020 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.Publication Metadata only Evaluation of Nutrition Knowledge of Pregnant Women before and after Nutrition Education according to Sociodemographic Characteristics(TAYLOR & FRANCIS INC, 2018) KARĞIN, DİCLE; Aktac, Sule; Sabuncular, Guleren; Kargin, Dicle; Gunes, Fatma EsraThe aim of this cross-sectional study is to evaluate the effect of nutrition education on nutritional knowledge levels of pregnant women. The study was undertaken on a sample of pregnant women (i = 743) attending health centers in Istanbul for prenatal care. Nutrition knowledge scores were significantly higher in posttest (23.0) than pretest (16.0) after receiving nutrition education (p < .001). Significant differences in pretest (p < .05) but not posttest (p > .05) scores were found for factors, such as education level, work status, and the number of pregnancies; significant differences in both test scores were found for age and nutrition information (p < .05). In conclusion, pregnant women need to be given adequate and appropriate nutrition education for maternal and child health according to sociodemographic characteristics.Publication Metadata only The relationship between eating attitude and behaviors with self-esteem of the university students(CUMHURIYET UNIV TIP FAK PSIKIYATRI ANABILIM DALI, 2015) GÜNEŞ, FATMA ESRA; Gunes, F. Esra; Calik, K. Burcu T.Objective: The purpose of this study is to determine the relationship between eating attitude and behaviors, self-esteems of the university students due to their age, psychosocial issues related to the environment. Methods: For his purpose, it was evaluated the eating attitude and behaviors in two different faculties of the same university (n=450). A cross-sectional random sampling method with the questionnaire was performed including demographic information, the Eating Attitudes Test and the Rosenberg Self-Esteem Test was administered. Results: As a result of statistical analysis a statistically significant difference of the eating attitude test scores with age, weight and average height. It didn't show significant difference between the mean scores of BMI values and mean scores of self-esteem levels. The students were grouped according to cut-off scores of the Eating Attitudes Test (EAT-40) and detected the statistical significant differences between the means of Rosenberg Self-Esteem Test subgroups scores (the self-esteem levels, relying on other people, interpersonal relationships to threats, participate in discussions and psychic isolation). Conclusion: Consequently, the significant relationship was not observed among students studying in different department of education who have eating disorders about their self-esteem risk. Students which studying in health-related department were more sensitivity than other group in the evaluation of eating attitudes and behaviors.